Science Daily: Pharmacology News
MARCH 27, 2024
Researchers have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia.
Drug Target Review
MARCH 28, 2024
Between 2000 and 2020, approximately 30 percent of the newly introduced small molecule drugs were derived from natural products. 1 Surprisingly, however, less than one percent of the natural world’s chemical composition has been identified or studied by scientists. While plant-derived molecules (phytochemicals) have long played an essential role in drug discovery due to their diverse biological activities and chemical properties, the reliance on time-consuming and expensive screening techniques
Drugs.com
MARCH 28, 2024
THURSDAY, March 28, 2024 -- Mpox cases are climbing again in the United States, with the number of reported infections now twice as high as they were at this time last year, new government data shows.In response, public health experts have raised.
DrugBank
MARCH 28, 2024
Space biosciences are on the verge of becoming one of the largest total addressable markets to ever exist, opening up vast opportunities for economic growth and scientific discovery. In the realm of space exploration, one critical yet often overlooked aspect is the impact of space conditions on human health. The goal of sending humans to space for increasingly longer periods of time is contingent on our ability to ensure astronauts' health.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
MARCH 27, 2024
What would you do if you walked up to a robot with a human-like head and it smiled at you first? You'd likely smile back and perhaps feel the two of you were genuinely interacting. But how does a robot know how to do this? Or a better question, how does it know to get you to smile back?
BioPharma Drive: Drug Pricing
MARCH 28, 2024
Xilio will get just over $40 million from Gilead in return for a license to its experimental IL-12 immunotherapy. The biotech is also discontinuing other work and laying off staff.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Antidote
MARCH 27, 2024
MS is a chronic disease that is estimated to impact over a million Americans. The condition causes damage to the body’s central nervous system, leading to numbness, memory problems, sight issues, and difficulties with coordination.
Science Daily: Pharmacology News
MARCH 28, 2024
A new bioluminescence imaging technique has created highly detailed, and visually striking, images of the movement of oxygen in the brains of mice. The method, which can be easily replicated by other labs, will enable researchers to more precisely study forms of hypoxia in the brain, such as the denial of oxygen to the brain that occurs during a stroke or heart attack.
BioPharma Drive: Drug Pricing
MARCH 25, 2024
The agency wants Regeneron to make more progress with a confirmatory trial before clearing odronextamab, a “bispecific” antibody being developed for multiple blood cancers.
Drugs.com
MARCH 29, 2024
FRIDAY, March 29, 2024 -- There has been a troubling rise in cases of a rare bacterial illness that can cause meningitis, U.S. health officials warned Thursday.In an alert issued to doctors, the U.S. Centers for Disease Control and Prevention said.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Broad Institute
MARCH 25, 2024
#WhyIScience Q&A: A cell biologist now helps recent college graduates launch their scientific careers By Leah Eisenstadt March 25, 2024 Breadcrumb Home #WhyIScience Q&A: A cell biologist now helps recent college graduates launch their scientific careers Alex Navarro draws from her scientific and personal experiences to guide young researchers toward their professional goals in the Broad’s post-baccalaureate program.
Science Daily: Pharmacology News
MARCH 25, 2024
A new study combining genetic, palaeoecological, and archaeological evidence has unveiled the Persian Plateau as a pivotal geographic location serving as a hub for Homo sapiens during the early stages of their migration out of Africa. It highlights the period between 70,000 to 45,000 years ago when human populations did not uniformly spread across Eurasia, leaving a gap in our understanding of their whereabouts during this time frame.
BioPharma Drive: Drug Pricing
MARCH 29, 2024
Confirmatory results for Krazati, which Bristol Myers acquired via its buyout of Mirati, could help the drug win full approval while Amgen has been set back.
Drugs.com
MARCH 28, 2024
THURSDAY, March 28, 2024 -- A strain of highly antibiotic-resistant gonorrhea first emerged in China in 2016, and cases of this tough-to-treat infection have tripled there in just five years, Chinese researchers report. It's a warning to the rest.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drug Target Review
MARCH 26, 2024
Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? DGG: I started my journey in STEM as a strategic consultant with various global pharmaceutical groups, working to solve specific strategic questions and being fully focused on one critical topic for a short time. After 10 years of supporting other teams, I wanted to become a full-time member and focus on using my analytic skills on a specific story that I believed in.
Science Daily: Pharmacology News
MARCH 28, 2024
Young to middle-aged women who reported drinking eight or more alcoholic beverages per week--more than one per day, on average--were significantly more likely to develop coronary heart disease compared with those who drank less, finds a study presented at the American College of Cardiology's Annual Scientific Session. The risk was highest among both men and women who reported heavy episodic drinking, or 'binge' drinking, and the link between alcohol and heart disease appears to be especially str
BioPharma Drive: Drug Pricing
MARCH 26, 2024
Merck is couting on Winrevair, which it acquired by buying Acceleron Pharma, to help soften the blow when Keytruda loses patent protection later this decade.
Drugs.com
MARCH 26, 2024
TUESDAY, March 26, 2024 -- Chemicals found in common household products might damage the brain's wiring, a new study warns. These chemicals -- found in disinfectants, cleaners, hair products, furniture and textiles -- could be linked to.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
KIF1A
MARCH 23, 2024
#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research Whole exome sequencing in Serbian patients with hereditary spastic paraplegia This year we’ve seen several studies investigating the genetics of hereditary spastic paraplegia (HSP), an umbr
Science Daily: Pharmacology News
MARCH 27, 2024
Researchers have recovered remarkably preserved microbiomes from two teeth dating back 4,000 years, found in an Irish limestone cave. Genetic analyses of these microbiomes reveal major changes in the oral microenvironment from the Bronze Age to today. The teeth both belonged to the same male individual and also provided a snapshot of his oral health.
BioPharma Drive: Drug Pricing
MARCH 26, 2024
The results are from a small Phase 1 study, but suggest Viking’s oral GLP-1 drug may not come with high rates of gastrointestinal side effects.
Drugs.com
MARCH 25, 2024
MONDAY, March 25, 2024 -- Drugmaker Eli Lilly & Co is announcing a temporary shortage of two of its insulin products."The 10 mL [millilter] vials of Humalog® and Insulin Lispro Injection are or will be temporarily out of stock at wholesalers.
Perficient: Drug Development
MARCH 29, 2024
Our colleagues in Atlanta had the wonderful opportunity to step into the world of competitive gaming as they met, and even got to play against multiple eMLS champion Paulo Neto! Paulo Neto represents Atlanta United and is a renowned eSports athlete Known for his prowess in FIFA. Paulo shared his insights into his journey as an esports athlete, shedding light on the skills and mindset required to succeed in the increasingly competitive world of eSports.
Science Daily: Pharmacology News
MARCH 25, 2024
Researchers have brought together two Nobel prize-winning research concepts to advance the field of quantum communication. Scientists can now efficiently produce nearly perfect entangled photon pairs from quantum dot sources.
BioPharma Drive: Drug Pricing
MARCH 28, 2024
The agency gave Akebia’s drug an OK after receiving more safety data, but imposed a strict boxed warning for its use that may limit uptake.
Drugs.com
MARCH 25, 2024
MONDAY, March 25, 2024 -- Federal regulators are taking a second stab at banning the controversial use of electroshock devices to manage the behavior of patients with intellectual and developmental disorders.The devices deliver electric shocks to a.
PLOS: DNA Science
MARCH 28, 2024
A new drug has entered the arsenal against Duchenne muscular dystrophy (DMD), a genetic disease that affects boys and is challenging to treat. Boys 6 years and older can take Duvystat, to slow the course of the illness. FDA classifies it as a “nonsteroidal treatment” – not a gene therapy, but it affects gene expression. DMD Basics DMD affects one in every 3500 to 6000 male births worldwide; that’s approximately 6 per 100,000 in North America and Europe, according to the M
Science Daily: Pharmacology News
MARCH 27, 2024
Scientists reversed an aggressive cancer, reverting malignant cells towards a more normal state. Rhabdoid tumors are an aggressive cancer which is missing a key tumor suppressor protein. Scientists discovered that removing a second protein from cancer cells already experiencing tumor suppressor loss can reverse cancer cell identity.
PPD
MARCH 26, 2024
The PPD clinical research business of Thermo Fisher Scientific conducts an annual survey of more than 150 leaders at pharmaceutical companies around the globe to assess trends in drug discovery and development, including preferences around outsourcing and functional service provider (FSP) utilization. The results of our most recent survey are now available in the 2024 FSP Trends Report , which explores utilization and growth projections, outlines the future of FSP strategies and models, and high
Drugs.com
MARCH 29, 2024
FRIDAY, March 29, 2024 -- People taking weight-loss drugs like Ozempic and Wegovy need to drop them in the days or weeks prior to surgery, a new study warns.Folks on one of these drugs -- known as GLP-1 receptor agonists -- have a 33% higher risk.
sptlabtech
MARCH 27, 2024
Biological research hinges on the collection and preservation of often precious samples for future analysis. Preserving sample integrity over time is crucial to avoiding degradation. Loss of integrity can lead to data loss or unreliable results, potentially jeopardizing research outcomes and incurring significant costs. Implementing robust and reliable sample management practices is key to giving you security in the integrity of your sample library and preventing costly disasters. arktic ® is ou
Science Daily: Pharmacology News
MARCH 25, 2024
Beautiful white wall paint does not stay beautiful and white forever. Often, various substances from the air accumulate on its surface. This can be a desired effect because it makes the air cleaner for a while -- but over time, the color changes and needs to be renewed. Now, special titanium oxide nanoparticles have been developed that can be added to ordinary, commercially available wall paint to establish self-cleaning power: The nanoparticles are photocatalytically active, they can use sunlig
addgene Blog
MARCH 26, 2024
While the antibodies present throughout our bodies carry out plenty of roles just the way they are, the research antibodies in your refrigerator often need a little help to be useful. Mainly because, well, antibodies are kind of hard to see. To solve this issue, researchers conjugate various labels to antibodies that produce detectable signals like light or color.
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