Sat.Jun 10, 2023 - Fri.Jun 16, 2023

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Verve partners with Lilly on gene editing therapy for heart disease

BioPharma Drive: Drug Pricing

Lilly will pay the genetic medicine specialist $60 million upfront to work together on a treatment targeting a risk factor known as Lp(a).

Therapies 310
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Most Women With Early Breast Cancer Will Become Long-Term Survivors, New Study Shows

Drugs.com

WEDNESDAY, June 14, 2023 -- Most women diagnosed with early breast cancer will become long-term survivors, according to new research that finds a substantial reduction in the risk of death since the 1990s. This news should reassure both patients and.

Research 299
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10-year countdown to sea-ice-free Arctic

Science Daily: Pharmacology News

Research team predicts Arctic without ice by the end of 2030s if current increasing rate of greenhouse gas emission continues.

Research 279
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Small Molecules Evolve

Drug Hunter

Small molecule drugs make up most of the drugs we take conveniently as pills, including painkillers like ibuprofen (Advil), antibiotics like penicillin and amoxicillin, or cholesterol-lowering drugs like atorvastatin (Lipitor). The biotechnology revolution allowed scientists to create drugs through genetic engineering and related biological processes, creating a new category of drugs known as “biologics.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Acadia gives once-rejected Prader-Willi drug a second chance

BioPharma Drive: Drug Pricing

The FDA last year turned back an approval request from the drug’s former developer, Levo Therapeutics. That biotech is now owned by Acadia, which will run a new study designed to boost its odds of success.

Drugs 282

More Trending

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Skipping evolution: Some kangaroos didn't hop

Science Daily: Pharmacology News

Extinct kangaroos used alternative methods to their famous hop according to comprehensive analysis.

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Molecules of the Month – May 2023

Drug Hunter

The post Molecules of the Month – May 2023 appeared first on Drug Hunter.

Drugs 130
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Illumina CEO Francis deSouza resigns weeks after surviving Icahn board battle

BioPharma Drive: Drug Pricing

DeSouza is departing unrepentant about his decision to close the Grail deal, telling colleagues his belief in the merger “remains unshakeable.

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FDA Approves Linzess to Treat Constipation in Children, Teens

Drugs.com

WEDNESDAY, June 14, 2023 -- The U.S. Food and Drug Administration approved Linzess (linaclotide) as a once-daily treatment for pediatric patients ages 6 to 17 years with functional constipation. The approval was based on data from 328 participants.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Study explains unusual deformation in Earth's largest continental rift

Science Daily: Pharmacology News

Computer models confirm that the African Superplume is responsible for the unusual deformations, as well as rift-parallel seismic anisotropy observed beneath the East African Rift System.

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Getting Real with Molecular Property Prediction

Practical Cheminformatics

Introduction If you believe everything you read in the popular press, this AI business is easy. Just ask ChatGPT, and the perfect solution magically appears. Unfortunately, that's not the reality. In this post, I'll walk through a predictive modeling example and demonstrate that there are still a lot of subtleties to consider. In addition, I want to show that data is critical to building good machine learning (ML) models.

Drugs 122
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Decentralized clinical trials (DCTs): protect your data to reduce risk

BioPharma Drive: Drug Pricing

Decentralized clinical trials (DCTs) bring many benefits to the clinical research process, and more importantly, the patients. However, it is important to remember the risks if there is no data security process in place.

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Lesbians, Gays Suffer More Mental Health Issues, Drug Use Problems: Survey

Drugs.com

WEDNESDAY, June 14, 2023 -- Lesbians, gays and bisexuals are experiencing more mental health and substance use issues than their heterosexual peers, researchers say. According to a new government report released Tuesday, this includes major.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Genome editing used to create disease resistant rice

Science Daily: Pharmacology News

Researchers have used the genome-editing tool CRISPR-Cas to create disease resistant rice plants, according to a new study. Small-scale field trials in China show that the newly created rice variety exhibited both high yields and resistance to the fungus that causes a serious disease called rice blast.

Disease 265
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Puerto Rico on Gene & Cell Therapy: An Unparalleled Proposal for Non-Dilutive Funding

Fierce BioTech

Puerto Rico: A Hub of Opportunity for Non-Dilutive Funding | Puerto Rico is becoming the best place in the world to conduct R&D activities for emerging technologies. Could your organization maximize growth potential by capitalizing on Puerto Rico’s unique tax incentives & culture of innovation?

Therapies 119
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A cell therapy startup looks to an IPO to avert financial peril

BioPharma Drive: Drug Pricing

In a sign of the impact the downturn has had on young biotechs, Turnstone Biologics, a former partner of Takeda and AbbVie, is seeking an IPO while acknowledging there is “substantial doubt” it can survive.

Therapies 198
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FDA Advisers Say Next Round of COVID Booster Shots Should  Target an XBB Variant

Drugs.com

THURSDAY, June 15, 2023 -- An advisory panel to the U.S. Food and Drug Administration voted unanimously on Thursday to recommend that COVID booster shots be updated for the fall to protect solely against one of the three XBB variants that have taken.

FDA 290
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Illusions are in the eye, not the mind

Science Daily: Pharmacology News

Numerous visual illusions are caused by limits in the way our eyes and visual neurones work -- rather than more complex psychological processes, new research shows.

Research 243
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Researchers identify gut microbiome signatures linked to precancerous colon polyps

Broad Institute

Researchers identify gut microbiome signatures linked to precancerous colon polyps By Tom Ulrich June 14, 2023 Breadcrumb Home Researchers identify gut microbiome signatures linked to precancerous colon polyps New study looks at gut microbes' influence, findings may help with prevention By MGH News And Public Affairs June 14, 2023 Credit: NCI Center for Cancer Research Human colon cancer cells.

Research 105
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Novo Nordisk to invest over $2B in drug ingredient production

BioPharma Drive: Drug Pricing

The company said the spending will help it manufacture future treatments for chronic diseases, adding to a string of recent plant investments.

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Gas Stove Chemical Tied to Higher Risk of Leukemia

Drugs.com

FRIDAY, June 16, 2023 -- Using gas stoves can increase indoor air levels of benzene, a chemical linked to higher risk of leukemia and other blood cell cancers, a new study reports. Analysis of dozens of stoves revealed that a single gas cooktop.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Key building block for life found at Saturn's moon Enceladus

Science Daily: Pharmacology News

The search for extraterrestrial life in our solar system just got more exciting. A team of scientists has discovered new evidence that the subsurface ocean of Saturn's moon Enceladus contains a key building block for life. The team directly detected phosphorus in the form of phosphates originating from the moon's ice-covered global ocean using data from NASA's Cassini mission.

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Synthesis and preliminary evaluation of benzylaminoimidazoline derivatives as novel norepinephrine transporter ligands

Chemical Biology and Drug Design

Novel benzylaminoimidazoline derivatives targeting NET were designed and prepared. For compound 9 , IC 50  = 5.65 ± 0.97 μM. [ 125 I]9 displayed specific affinity for NET both in vitro and in vivo. Abstract A series of benzylaminoimidazoline derivatives was synthesized and evaluated for norepinephrine transporter (NET) targeting. Among them, N-(3-iodobenzyl)-4,5-dihydro-1H-imidazol-2-amine (Compound 9 ) displayed the highest affinity for NET (IC 50  = 5.65 ± 0.97 μM).

Research 100
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AbbVie, Coherus mend dispute over low-price Humira biosimilar

BioPharma Drive: Drug Pricing

The biosimilar developer’s plans to set steep discounts on its copycat version of AbbVie’s Humira set off a legal back-and-forth between the companies.

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What Is Chronic Acid Reflux, or GERD?

Drugs.com

FRIDAY, June 16, 2023 -- Is heartburn keeping you awake? Do you experience a bitter taste in your mouth? Your doctor says you have GERD, but what is GERD? Gastroesophageal reflux disease (GERD) occurs when the contents of your stomach move up into.

Doctors 278
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Fossil study sheds light on famous spirals found in nature

Science Daily: Pharmacology News

A 3D model of a 407-million-year-old plant fossil has overturned thinking on the evolution of leaves. The research has also led to fresh insights about spectacular patterns found in plants.

Research 228