Sat.Jul 08, 2023 - Fri.Jul 14, 2023

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First nonprescription birth control pill approved by FDA

BioPharma Drive: Drug Pricing

The oral contraceptive’s maker, Perrigo, said the pill will be available in drug and grocery stores early next year, but did not disclose its planned price.

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B 7/14 -- Lisa Marie Presley Died of Common Complication of Weight-Loss Surgery

Drugs.com

FRIDAY, July 14, 2023 -- Lisa Marie Presley, the daughter of Elvis Presley, died from complications of a weight-loss surgery she had several years ago, according to an autopsy report released Thursday. The singer/songwriter died Jan. 12 of natural.

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The ocean's color is changing as a consequence of climate change

Science Daily: Pharmacology News

The ocean's color has changed significantly in 20 years, and the trend is likely a consequence of human-induced climate change, report scientists.

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Longevity Biotech Startup Gero Demonstrates the Power of Quantum Computing in Drug Design

Drug Discovery Today

Research published in Nature Scientific Reports builds on earlier work and demonstrates that commercially available quantum computing services can dramatically accelerate discovery of a new universe of unique chemical structures that are synthetically feasible and possess drug-like properties for tackling complex diseases and aging

Drugs 184
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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European regulators probe suicide risk to Ozempic, other Novo drug Saxenda

BioPharma Drive: Drug Pricing

Three reports from Iceland spurred the EMA to evaluate whether certain Novo Nordisk drugs, including Ozempic, might cause thoughts of self harm.

More Trending

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Multiple ecosystems in hot water after marine heatwave surges across the Pacific

Science Daily: Pharmacology News

Rising ocean temperatures are sweeping the seas, breaking records and creating problematic conditions for marine life. Unlike heatwaves on land, periods of abrupt ocean warming can surge for months or years. Around the world these 'marine heatwaves' have led to mass species mortality and displacement events, economic declines and habitat loss. New research reveals that even areas of the ocean protected from fishing are still vulnerable to these extreme events fueled by climate change.

Research 246
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Upcoming Webinar: Buildup or pare down – fragment and full molecule-based molecular design trends in the age of AI

Collaborative Drug

Upcoming Webinar: Buildup or pare down – fragment and full molecule-based molecular design trends in the age of AI

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RNA editing specialist Korro to go public via reverse merger

BioPharma Drive: Drug Pricing

The deal with Frequency Therapeutics is the latest biotech reverse merger as private drugmakers still face challenges going public via an IPO.

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Racial Discrimination Raises Risk for Childhood Obesity

Drugs.com

FRIDAY, July 14, 2023 -- Racial discrimination may drive health inequities from an early age, according to researchers who found that it puts kids at risk for obesity. “Exposure to racial discrimination must be acknowledged as both a social.

Research 246
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Revolutionary self-sensing electric artificial muscles

Science Daily: Pharmacology News

Researchers have made groundbreaking advancements in bionics with the development of a new electric variable-stiffness artificial muscle. This innovative technology possesses self-sensing capabilities and has the potential to revolutionize soft robotics and medical applications. The artificial muscle seamlessly transitions between soft and hard states, while also sensing forces and deformations.

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N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics

Covalent Modifiers

Nat Commun 14 , 3564 (2023). [link] Cysteine has been exploited as the binding site of covalent drugs. Its high sensitivity to oxidation is also important for regulating cellular processes. To identify new ligandable cysteines which can be hotspots for therapy and to better study cysteine oxidations, we develop cysteine-reactive probes, N-acryloylindole-alkynes (NAIAs), which have superior cysteine reactivity owing to delocalization of π electrons of the acrylamide warhead over the whole indole

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Lilly to buy Versanis, adding to obesity drug pipeline

BioPharma Drive: Drug Pricing

The pharma will pay up to $1.9 billion to acquire the private biotech and its experimental antibody, which Lilly plans to pair with its own weight loss medicines.

Drugs 246
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WHO Agency Declares Aspartame a Possible Carcinogen

Drugs.com

FRIDAY, July 14, 2023 -- In findings that are likely to fuel the debate over the safety of aspartame, one World Health Organization (WHO) agency announced Thursday that the artificial sweetener is a possible carcinogen while another stood firm in.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Reinventing cosmology: New research puts age of universe at 26.7 -- not 13.7 -- billion years

Science Daily: Pharmacology News

Our universe could be twice as old as current estimates, according to a new study that challenges the dominant cosmological model and sheds new light on the so-called 'impossible early galaxy problem.

Research 208
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Cover Image

Chemical Biology and Drug Design

Cover Image © molekuul_be/Shutterstock.

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Avrobio halts gene therapy research and considers a sale

BioPharma Drive: Drug Pricing

The decision to explore “strategic alternatives” comes about six weeks after the company sold its most advanced treatment to Novartis for nearly $90 million.

Therapies 246
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First Murder Conviction for Fentanyl Dealer Delivered in California

Drugs.com

TUESDAY, July 11, 2023 -- A fentanyl dealer has been found guilty of second-degree murder in what authorities believe is the first-ever murder conviction for dealing the dangerous drug. The conviction happened in Placer County, Calif., in a case.

Drugs 246
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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The ground is deforming, and buildings aren't ready

Science Daily: Pharmacology News

A new study has linked underground climate change to the shifting ground beneath urban areas. The phenomenon is affecting all major urban areas around the globe, causing civil structures and infrastructures to crack.

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Agent-based modelling reveals the role of the tumour microenvironment on the short-term success of combination temozolomide/immune checkpoint blockade to treat glioblastoma [Chemotherapy, Antibiotics, and Gene Therapy]

ASPET

Glioblastoma is the most common and deadly primary brain tumour in adults. All glioblastoma patients receiving standard-of-care surgery-radiotherapy-chemotherapy (i.e., temozolomide-TMZ) recur, with an average survival time of only 15 months. New approaches to the treatment of glioblastoma, including immune checkpoint blockade and oncolytic viruses, offer the possibility of improving glioblastoma outcomes and have as such been under intense study.

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EMA expands probe of possible suicide risk to popular weight loss, diabetes drugs

BioPharma Drive: Drug Pricing

The European drug regulator says it now has 150 reports of possible cases involving self-injury and suicidal thoughts among people taking GLP-1 medicines like Ozempic.

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New Type of Treatment Tackles Tough-to-Treat Prostate Cancer

Drugs.com

THURSDAY, July 13, 2023 -- A preclinical study offers a potential new therapy for treatment-resistant prostate cancer, offering new hope for men with the disease. The study used the chemotherapy drug cisplatin, administered orally, to disrupt the.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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The sound of silence? Researchers demonstrate people hear it

Science Daily: Pharmacology News

Silence might not be deafening but it's something that literally can be heard, concludes a team of philosophers and psychologists who used auditory illusions to reveal how moments of silence distort people's perception of time.

Research 208
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Differential Efficacy of Small Molecules Dynasore and Mdivi-1 for the Treatment of Dry Eye Epitheliopathy or as a Countermeasure for Nitrogen Mustard Exposure of the Ocular Surface [Cellular and Molecular]

ASPET

The ocular surface comprises the wet mucosal epithelia of the cornea and conjunctiva, the associated glands, and the overlying tear film. Epitheliopathy is the common pathological outcome when the ocular surface is subjected to oxidative stress. Whether different stresses act via the same or different mechanisms is not known. Dynasore and dyngo-4a, small molecules developed to inhibit the GTPase activity of classic dynamins DNM1, DNM2 and DNM3, but not mdivi-1, a specific inhibitor of DNM1L, pro

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Startup Tenpoint raises $70M to develop regenerative medicines for the eye

BioPharma Drive: Drug Pricing

Backed by F-Prime Capital and Sofinnova Partners, the company claims to have technology that could allow it replace eye cells destroyed in age-related and inherited ocular conditions.

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Nearly 1 in 5 Say Their Workplace Can Be Toxic, Poll Finds

Drugs.com

THURSDAY, July 13, 2023 -- About one-fifth of American workers say their workplace is toxic, and many say their mental health is harmed as a result. The American Psychological Association (APA) questioned 2,515 employed adults in April for its.

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Genes for learning and memory are 650 million years old

Science Daily: Pharmacology News

Scientists have discovered that the genes required for learning, memory, aggression and other complex behaviors originated around 650 million years ago.

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