Drug Hunter

JULY 21, 2023

With the popular success of diabetes and weight-loss peptide drugs from Novo (e.g. semaglutide/Ozempic), this month features a pair of ultra-hot non-peptide oral GLP-1R modulators in clinical development. Other notable Molecules of the Month include vorasidenib, which demonstrated headline-generating efficacy in brain cancers, as well as controversial billion-dollar molecule atrasentan, the subject of a short-seller report by Muddy Waters.

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Structure Based Drug Design (SBDD) Targeted Protein Degradation Clinical Trials Trials 227

Forbes: Drug Truths

JULY 21, 2023

Unfortunately, Becerra’s rhetoric reinforces many misconceptions about the history of the discovery and development of the Covid-19 vaccines, work that was critical in.

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BioPharma Drive: Drug Pricing

JULY 17, 2023

For $500 million, Novartis will acquire DTx Pharma and its preclinical neurological disease drugs, marking the Swiss company’s latest investment in gene-silencing medicines.

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Drugs.com

JULY 21, 2023

FRIDAY, July 21, 2023 -- Aspirin, naproxen and other common pain medications known as NSAIDs worsen gastrointestinal infections caused by a bacterium known as Clostridioides difficile (C. diff), new research shows. NSAIDs (nonsteroidal.

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Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Broad Institute

JULY 20, 2023

A look back at the first year of NeuroDev By Makenzie Kohler July 20, 2023 Breadcrumb Home A look back at the first year of NeuroDev Researchers are working to characterize the genetic and phenotypic data of people with neurodevelopmental conditions in Kenya and South Africa. By Makenzie Kohler July 20, 2023 Credit: Aga Khan University Institute for Human Development NeuroDev researchers from Kenya, South Africa, and the United States at a meeting in Nairobi, Kenya.

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Forbes: Drug Truths

JULY 20, 2023

In order to promote its weight-loss and diabetes drugs, Novo Nordisk bought doctors almost a half a million meals in 2022.

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Doctors Drugs 188

Drugs.com

JULY 20, 2023

THURSDAY, July 20, 2023 -- It’s difficult to fully predict who will develop Alzheimer’s disease in advance. Now, a new study suggests that certain markers in the blood may occur 10 to 20 years before the start of symptoms and could help.

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Broad Institute

JULY 19, 2023

Researchers reprogram gene therapy viral vectors to bind specific protein targets By Allessandra DiCorato July 19, 2023 Breadcrumb Home Researchers reprogram gene therapy viral vectors to bind specific protein targets A new screening method zeroes in on adeno-associated viruses that enter the brain through a defined mechanism. By Allessandra DiCorato July 19, 2023 Credit: Kevin Middleton, Broad Communications A three-dimensional model of adeno-associated viruses (AAVs), which scientists have eng

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Science Daily: Pharmacology News

JULY 18, 2023

No, oxygen didn't catalyze the swift blossoming of Earth's first multicellular organisms. The result defies a 70-year-old assumption about what caused an explosion of oceanic fauna hundreds of millions of years ago.

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BioPharma Drive: Drug Pricing

JULY 18, 2023

The unusual research alliance involves the startup creator’s Pioneering Medicines initiative, which previously struck pacts with Novo Nordisk and the Cystic Fibrosis Foundation.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drugs.com

JULY 20, 2023

THURSDAY, July 20, 2023 -- Every day, millions of people must take one or more pills to control their blood pressure and reduce their risk for heart attack or stroke, but if new research pans out, some may be able to scrap their pills for a.

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Trials Research 98

Perficient: Drug Development

JULY 17, 2023

Perficient is proud of our people-first, award-winning culture that promises to challenge, champion, and celebrate all our colleagues. Perficient is always looking to hire thought leaders and difference makers, and therefore, identifying top talent is essential to our mission. Katie Burwell , a senior talent acquisition specialist, is helping to grow our talented team of experts.

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Drug Target Review

JULY 18, 2023

Artificial Intelligence (AI) is poised to transform the field of target discovery in drug development, offering immense potential to enhance efficacy, personalised medicine, and accelerate the development of innovative compounds. However, as AI becomes increasingly integrated into the drug discovery process , challenges related to data quality, collaboration, and regulatory adaptation need to be addressed to ensure its successful implementation.

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KIF1A

JULY 15, 2023

#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research Hidden behavioral fingerprints in epilepsy Epilepsies are disorders of electrical activity in the central nervous system.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drugs.com

JULY 20, 2023

THURSDAY, July 20, 2023 (American Heart Association News) -- New guidelines detailing how to care for people with heart disease come with some easy-to-grasp warnings for patients. The chronic coronary disease guidelines from the American Heart.

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Perficient: Drug Development

JULY 21, 2023

Effective and efficient employee communication is critical to the success of any organization. Microsoft Viva Connections, a part of the Microsoft Viva platform, has been making waves as a powerful tool for transforming the way companies interact with their employees. Let’s take a look into some key features of Viva Connections and discover how its changing employee engagement and communication: Meet your Employees Where they Work One of the most important features Connections brings is th

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Government 98

biobide

JULY 21, 2023

The Microbiota-Gut-Brain axis (MGBA) is a topic of interest that has gained attention and recognition in the scientific community over the past years. The gut–brain axis includes the central nervous, endocrine, and immune systems, and it is an information exchange network that connects the gut and the brain. It can transmit information bidirectionally: “top–down” from the brain to the gut and “bottom–up” from the gut to the brain.

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BioPharma Drive: Drug Pricing

JULY 17, 2023

An organization of retinal specialists flagged six cases of severe eye inflammation from commercial use of Syfovre. Apellis says the drug’s safety profile is consistent with testing.

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Drugs 97

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

JULY 19, 2023

WEDNESDAY, July 19, 2023 (American Heart Association News) -- After a night of partying, 29-year-old Bethany Moeddel felt nauseous and had a headache. A hangover, she figured. She couldn't sleep it off, though, because it was a big day. Her.

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SCIENMAG: Medicine & Health

JULY 21, 2023

Analysing satellite data spanning the past 20 years, the research team based at the Cavendish Laboratory in Cambridge examined how vegetation has been changing along the Pacific coast of Peru and northern Chile. This area is known for its unique and delicate arid and semi-arid environments.

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Laboratories Research 94

Perficient: Drug Development

JULY 18, 2023

Introduction The Content Recommendations add-on for Optimizely CMS dynamically recommends content from your site tailored to the interests of each user. Installing the NuGet Package will give you access to Optimizely’s Content Recommendations Block which uses Mustache Templating to render the data from the Content Recommendations API on a page. Although Mustache Templates provide a great way of inserting recommendation data into a webpage, content authors who don’t have prior experience wi

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BioPharma Drive: Drug Pricing

JULY 21, 2023

The Swiss drugmaker now joins a lengthy list of biotechs that, amid a drawn-out market downturn, have turned to job cuts and research re-evaluations to save money.

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Drugs.com

JULY 21, 2023

FRIDAY, July 21, 2023 -- Scientists have reported a link between air pollution and dementia risk, but they haven't had a good understanding of the mechanisms behind this association. Now, a new study provides some answers. “In this study, we found.

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SCIENMAG: Medicine & Health

JULY 18, 2023

Biomolecular condensates, the tiny combinations of proteins and mRNA forming membrane-less compartments within cells, have big potential implications for the future of not just plants but humans.

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Research 94

Fierce BioTech

JULY 17, 2023

From Bench to Bedside and Back Again: Strategies for Effectively Leveraging Pre-Clinical Data to Accelerate R&D dwunderlin Mon, 07/17/2023 - 16:55 Thu, 09/07/2023 - 11:00 Resource Type Webinar Duration 60 Minutes The drug discovery process is complex and time-consuming, with an average development time of 10+ years and hundreds of millions to billions of dollars spent to receive regulatory approval.

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Clinical Trials Drug Development Research Trials 88

BioPharma Drive: Drug Pricing

JULY 17, 2023

Leaders from the firm said that, despite a turbulent biotech market, most of their existing limited partners returned to participate in the new fund, which will support approximately a dozen startups.

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Marketing 94

Drugs.com

JULY 18, 2023

TUESDAY, July 18, 2023 -- Fluoride may have found its match in preventing cavities. New research shows that toothpaste containing hydroxyapatite, one of the main mineral components in teeth, can prevent cavities as effectively as fluoride, which has.

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Research 98

SCIENMAG: Medicine & Health

JULY 17, 2023

NEW YORK, NY–A pair of new studies led by researchers at Columbia University explains why babies get so many common respiratory infections and identifies a specialized cluster of immune cells found only in babies that help them better cope with new pathogens.

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Research 94

Science Daily: Pharmacology News

JULY 21, 2023

A large portion of Greenland was an ice-free tundra landscape -- perhaps covered by trees and roaming woolly mammoths -- in the recent geologic past (about 416,000 years ago), a new study shows. The results help overturn a previous view that much of the Greenland ice sheet persisted for most of the last two and a half million years. Instead, moderate warming, from 424,000 to 374,000 years ago, led to dramatic melting.

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BioPharma Drive: Drug Pricing

JULY 18, 2023

The startup, a developer of gene therapies for brain diseases like Rett Syndrome, will bypass an IPO by merging with struggling cancer drugmaker Neoleukin.

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Drugs.com

JULY 17, 2023

MONDAY, July 17, 2023 -- Writing letters, taking classes and playing mentally stimulating games like chess in your older years could lower your risk of dementia over the next decade, a new study suggests. Researchers in Australia found that.

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Research 98

SCIENMAG: Medicine & Health

JULY 19, 2023

Covalent organic frameworks (COFs) are versatile materials composed of interconnected organic molecules held together by covalent bonds. These frameworks can be constructed in two-dimensional or three-dimensional (3D) forms which possess a unique combination of low density, high surface area, and easily tunable properties.

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Drug Channels

JULY 21, 2023

Today’s guest post comes from Brent Clifton, Vice President of Product Management at CoverMyMeds. Brent discusses the challenges that patients, caregivers, and providers face when seeking access to medications requiring prior authorization. He explains how an electronic prior authorization solution can reduce delays and help patients start their therapies sooner—especially when patients and brands can play an active role in the process.

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