Drug Discovery World

AUGUST 25, 2023

DDW’s Megan Thomas looks at a day in the life of Giusy Di Conza , Head of Research at iOnctura. MT: Where do you work, and can you tell us what you’re working on at the moment? GDC : I’m Head of Research for a young, dynamic biotech called iOnctura. We are pioneering research into new biological mechanisms for established drug targets. Whereas traditionally biotechs have studied the effect of a drug on a singular pathway, we are focused on targets that are involved in multiple independent tumour

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BioPharma Drive: Drug Pricing

AUGUST 23, 2023

The company doesn’t know if the needles have caused retinal vasculitis in some people receiving its geographic atrophy drug Syfovre, but is no longer recommending their use.

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Drugs.com

AUGUST 25, 2023

FRIDAY, Aug. 25, 2023 -- Paper straws, meant to be an eco-friendly alternative to plastic, may not be better for the environment, a new study concludes, warning that they also contain “forever chemicals” that can harm human.

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FDA Law Blog: Biosimilars

AUGUST 24, 2023

Hyman, Phelps & McNamara, P.C. (“HP&M”) is is proud to announce that 14 of the Firm’s attorneys have been selected to the 2024 edition of The Best Lawyers in America®. Newly recognized this year are attorneys Josephine M. Torrente (FDA Law), Michelle L. Butler (FDA Law), Sara W. Koblitz (FDA Law), Allyson B. Mullen (FDA Law), and Anne K. Walsh (FDA Law), as well as McKenzie E.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

AUGUST 25, 2023

As negotiations continue between the UK and EU over Horizon Europe, the largest collaborative research programme in the world, the scientific research community has urged the Prime Minister to secure the UK’s membership as soon as possible. Figures reported in The Guardian from the European Commission emphasise the importance of the programme to UK research.

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BioPharma Drive: Drug Pricing

AUGUST 22, 2023

Billing itself as both a scientific and investment partner, Foundery aims to provide research grants and drug development support to researchers developing new immunotherapies.

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Perficient: Drug Development

AUGUST 24, 2023

The transition from a wholesale-centric business model to include a new direct-to-consumer (D2C) approach presents lucrative opportunities alongside a suite of technical and operational intricacies to consider. While the move brings manufacturing companies closer to end consumers, it also requires several considerations spanning content creation, post-purchase support, and overall brand experience.

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Drug Discovery World

AUGUST 21, 2023

Talus Bio has received $4.3 million in new grants from the National Institutes for Health (NIH) and the Washington State Andy Hill CARE Fund to advance its paediatric cancer therapeutics. The Seattle-based company received two grants totalling $2.3M from the CARE Fund to fuel the discovery of new transcription factor inhibitors for rhabdomyosarcoma and neuroblastoma, two childhood cancers.

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BioPharma Drive: Drug Pricing

AUGUST 25, 2023

According to one analyst, the approval was the last hurdle keeping Sandoz’s Tyruko from directly competing in the U.S. market against Biogen’s inflammation-regulating medicine Tysabri.

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Drugs.com

AUGUST 25, 2023

FRIDAY, Aug. 25, 2023 -- Alice Tapper felt deathly ill, suffering from severe abdominal pain, a 102-degree fever and vomiting. Emergency room doctors found that Alice -- the daughter of CNN anchor Jake Tapper -- had a rapid pulse of 135 beats per.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drug Target Review

AUGUST 24, 2023

The focus of this study is on Growth Differentiation Factor-15 (GDF-15), a cytokine known for its critical role in feto-maternal tolerance, which has now been found to be hijacked by tumours to evade immune attack. We will explore how GDF-15 impacts the tumour microenvironment and hinders the infiltration of T cells into the tumour, as well as the implications of neutralising GDF-15 to reverse its inhibitory effects and sensitise tumours to anti-PD-1 treatment.

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Drug Channels

AUGUST 25, 2023

Today’s guest post comes from Chris Dowd, Senior Vice President of Market Development at ConnectiveRx. Chris discusses how such copay adjustment programs as accumulators and maximizers impact patients. He also discusses current legal cases that cover prescription medication access. To learn more, register for ConnectiveRx’s free October online panel discussion with Chris: The Battle Over Accumulators and Maximizers: What You Need to Know for 2024.

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BioPharma Drive: Drug Pricing

AUGUST 23, 2023

Data inadvertently published from a closely watched lung cancer study suggest a drug blocking the protein TIGIT may help extend survival, a finding that boosted shares of other developers.

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Drugs.com

AUGUST 25, 2023

FRIDAY, Aug. 25, 2023 -- It might not seem like constipation or difficulty swallowing could signal a neurological problem, but new research suggests that these gut conditions could be an early indicator of Parkinson’s disease. Gastrointestinal.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Antidote

AUGUST 21, 2023

Before any new treatment is able to be approved, it is required to go through the vigorous testing process known as clinical trials. These trials are aimed at determining whether or not a drug, medical device, therapy, or other type of intervention is safe and effective for the public.

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Drug Patent Watch

AUGUST 21, 2023

Loss of exclusivity (LOE) doesn’t have to spell doom for branded drug revenue streams. In the face of impending patent expirations, pharmaceutical companies can adopt key approaches to preserve meaningful… The post Strategies to Maximize Product Value Amid Loss of Exclusivity in the Pharmaceutical Industry appeared first on DrugPatentWatch - Make Better Decisions.

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Perficient: Drug Development

AUGUST 22, 2023

Aria labels provide alternate text to adaptive technology tools such as screen readers. This helps website visitors navigate the site more accurately. One use case for aria-labels is on html anchor tags. Sitecore does not a way to manage this text by default. Follow along and I’ll show you how to modify the various link dialogs and give content authors the ability to manage this text.

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Drugs.com

AUGUST 25, 2023

FRIDAY, Aug. 25, 2023 -- Coupons for tobacco products appear to have a big impact on relapse rates for smokers who have recently kicked the habit, researchers report. A study of more than 5,000 former smokers who participated in a national survey.

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SCIENMAG: Medicine & Health

AUGUST 22, 2023

PROVIDENCE, R.I. [Brown University] — One of the most common and practically useful experiments in all of fluid dynamics involves holding an object in air or submerging it fully underwater, exposing it to a steady flow to measure its resistance in the form of drag.

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Drug Target Review

AUGUST 21, 2023

To unravel the mysteries behind the treatment response, researchers from the Department of Otolaryngology/Head and Neck Surgery at UNC School of Medicine collaborated with experts from Yale Cancer Center, the Yale Head and Neck Cancer Specialised Program of Research Excellence (SPORE), and the ECOG-ACRIN Cancer Research Group. Their study, published in Proceedings of the National Academy of Sciences , unveiled the existence of two distinct subtypes of HPV + head and neck cancers.

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Perficient: Drug Development

AUGUST 22, 2023

To meet clinical, business, and evolving consumer needs, healthcare and life sciences organizations are focused on care delivery that enables innovation in patient engagement, data and analytics, and virtual care. According to Gartner’s 2022 Industry Cloud Survey , about 40% of IT leaders say they have started to adopt industry cloud platforms, with another 15% in pilots; another 15% are considering deployment by 2026.

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Drugs.com

AUGUST 25, 2023

FRIDAY, Aug. 25, 2023 -- The U.S. Food and Drug Administration approved Tyruko (natalizumab-sztn), the first biosimilar to Tysabri (natalizumab) injection, for the treatment of relapsing forms of multiple sclerosis, the agency announced.

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BioPharma Drive: Drug Pricing

AUGUST 22, 2023

The pharma’s suit, which claims Medicare’s new power to negotiate certain drug prices is unconstitutional, comes days before the agency will reveal the first 10 medicines to be included under the plan.

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Fierce BioTech

AUGUST 24, 2023

In this podcast, Dan Fisher, managing director for IPM.ai, a division of Real Chemistry, explains how real world health data generated from more than 300 million de-identified patient records can h | Using artificial intelligence to predict and uncover de-identified rare disease patients shortens the time to diagnosis, benefiting both patients and life science companies.

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Perficient: Drug Development

AUGUST 21, 2023

If you’ve been following Sitecore’s architectural movement over the last few years, a lot has changed. Instead of the “all-in-one” approach of Sitecore XP, XM Cloud , and Headless encourage a composable architecture – one where Sitecore itself offers 11 SaaS products categorized into three clouds : Content Cloud, Engagement Cloud, and Commerce Cloud.

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Drugs.com

AUGUST 25, 2023

FRIDAY, Aug. 25, 2023 -- The U.S. Food and Drug Administration approved Tyruko (natalizumab-sztn), the first biosimilar to Tysabri (natalizumab) injection, for the treatment of relapsing forms of multiple sclerosis, the agency announced.

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BioPharma Drive: Drug Pricing

AUGUST 23, 2023

The funding for Rapport Therapeutics saw participation from a series of so-called crossover investors, many of which have pulled back from biotech startups in recent years.

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SCIENMAG: Medicine & Health

AUGUST 22, 2023

Amsterdam, Netherlands – 23 Aug 2023: Hours of inactivity during childhood could be setting the stage for heart attacks and strokes later in life, according to research presented at ESC Congress 2023.

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Perficient: Drug Development

AUGUST 23, 2023

Today’s environment is relentlessly volatile. It rewards speed over size, agility over efficiency, and cross-functional flow over rigid structure. You must be ready to shift and scale your teams as priorities change. The way forward requires a comprehensive digital strategy that defines the capabilities, agility, and alignment to put you on the right side of digital disruption.

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Drugs.com

AUGUST 24, 2023

THURSDAY, Aug. 24, 2023 -- Cancer patients with immune systems weakened by treatment are among the groups most concerned about the continued spread of COVID-19 and the chance of the infection becoming severe. New research suggests more guidance on.

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BioPharma Drive: Drug Pricing

AUGUST 24, 2023

Bristol Myers Squibb is among those backing the startup, which claims the manufacturing capacity at its New Jersey plant can surpass that of conventional CDMO facilities.

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SCIENMAG: Medicine & Health

AUGUST 23, 2023

NEW YORK, August 23, 2023 — Physicist Matthew Sfeir is among 21 innovative mid-career scientists who will each receive $1.25 million from the Gordon and Betty Moore Foundation to pursue experimental physics research with the promise of significantly transforming understanding of physics and facilitating next-generation technological breakthroughs.

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Science Daily: Pharmacology News

AUGUST 24, 2023

The first three weeks of July 2023 have been the hottest global three-week period so far. Researchers report that the European population's exposure to heat was highest in Italy.

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Drugs.com

AUGUST 24, 2023

THURSDAY, Aug. 24, 2023 -- Stroll past the supplements in any drugstore and you’ll find broad claims about fish oil helping everything from heart and brain health, to joints, eyes and immune systems.

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