Drug Hunter
OCTOBER 5, 2023
With initial signs of efficacy and tolerability, Drug Hunter is launching into Phase III! To address your helpful feedback, we’ve rebuilt the platform from scratch to support new features and enhancements. In a few days, you’ll see the changeover to the new version go live. Show Me the Molecules! Fig. 1. The new homepage, which you can preview at v2.drughunter.com.
Broad Institute
OCTOBER 3, 2023
Broad Clinical Labs established to expand clinical services By Leah Eisenstadt October 3, 2023 Breadcrumb Home Broad Clinical Labs established to expand clinical services Formerly the Clinical Research Sequencing Platform, the cutting-edge laboratory at the Broad Institute is poised to further accelerate clinical genomics. By Broad Communications October 3, 2023 The Broad's Clinical Research Sequencing Platform is now Broad Clinical Labs.
Drug Target Review
OCTOBER 4, 2023
Antibody-drug conjugates (ADCs) have been a groundbreaking approach to cancer treatment with their ability to deliver cytotoxic drugs directly to diseased cells while sparing healthy tissues. This targeted delivery allows enhanced therapeutic efficacy while reducing the harmful side effects commonly associated with traditional chemotherapy. Here, we reflect on how ADCs and their payloads have changed, take a look at some of the less common payloads being explored in the treatment of cancer, and
BioPharma Drive: Drug Pricing
OCTOBER 6, 2023
The funding, which is part of ACT for ALS, will support expanded access studies of drugs developed by Prilenia Therapeutics, Clene Nanomedicine and Rapa Therapeutics.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
OCTOBER 6, 2023
THURSDAY, Oct. 5, 2023 -- A nasal spray containing a ketamine derivative appears to beat one of the standard drugs used for people with difficult-to-treat depression, a new clinical trial has found. The trial, of nearly 700 people with.
Broad Institute
OCTOBER 4, 2023
Cancer immunotherapy candidate provokes powerful dual response in cancer and immune cells By Allessandra DiCorato October 4, 2023 Breadcrumb Home Cancer immunotherapy candidate provokes powerful dual response in cancer and immune cells The small molecule, now in clinical trials, increases activity of immune cells and sensitivity of tumors to immune attack.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drug Target Review
OCTOBER 5, 2023
Published in the Journal of Neurology Neurosurgery & Psychiatry. This innovative approach involves the extraction of a patient’s own stem cells from either their bone marrow or blood , followed by a course of chemotherapy and antibody treatment. While aHSCT has shown potential benefits for RRMS patients, it has not yet garnered widespread inclusion in national clinical guidelines.
Drugs.com
OCTOBER 6, 2023
THURSDAY, Oct. 5, 2023 -- While many have raved about the powers of popular weight-loss drugs like Wegovy and Ozempic, new research confirms the medications can trigger some nasty gastrointestinal side effects. Known as GLP-1 agonists, they may.
Fierce BioTech
OCTOBER 5, 2023
Successful and worthwhile clinical trials rely on patient trust throughout the entire experience. | Greg Lever, Director within the IQVIA Applied Data Science Center, reveals how modeling technology is being used to unlock value and enhance the experience of trial participants.
Perficient: Drug Development
OCTOBER 5, 2023
Let’s Connect at the Puerto Rico CIO & IT Leadership Conference From October 12, 2023 to October 13, 2023, we will have several Perficient colleagues at the Puerto Rico IT Cluster’s CIO & IT Leadership conference to support companies in the region as they continue to transform through digital technology. Our industry, technology, and strategy capabilities place Perficient at the forefront of the technology space, and we are excited to engage with our peers at this year’s conference
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
LifeSciVC
OCTOBER 5, 2023
By Aoife Brennan, CEO of Synlogic, as part of the From The Trenches feature of LifeSciVC I remember vividly my first vacation with the man who would be my husband. In the days before Airbnb and on-line travel websites, he had all the books and had thoroughly researched each destination, every transport option, all the food venues. The guy clearly had process.
Drugs.com
OCTOBER 4, 2023
TUESDAY, Oct. 3, 2023 -- Federal regulators are cautioning doctors not to give probiotics to preterm infants. An infant given probiotics at an undisclosed hospital has died, U.S. Food and Drug Administration officials said in a recent warning.
BioPharma Drive: Drug Pricing
OCTOBER 2, 2023
The regulator is considering approval of what would be the first CRISPR medicine, as well as important clearances for Alnylam, Bristol Myers, Amgen and Pfizer.
Drug Target Review
OCTOBER 6, 2023
Dr Lonard is at the forefront of scientific innovation, spearheading CoRegen’s pioneering approach to immunotherapy by harnessing the power of Steroid Receptor Coactivator-3 (SRC-3). This master regulator of the regulatory T cell (Treg) genome has opened new horizons in the fight against cancer, offering a precise and tailored solution to modulate the immune system’s response.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
National Institute on Drug Abuse: Nora's Blog
OCTOBER 6, 2023
The power of protective layers: Employers advancing whole-person health mfleming Fri, 10/06/2023 - 17:56 Nora's Blog October 11, 2023 This blog was originally posted on LinkedIn.com. Image @GettyImages/ SolStock There is a growing movement among employers to holistically recognize employees’ mental, financial, and physical health through a "whole-person" approach.
Drugs.com
OCTOBER 2, 2023
MONDAY, Oct. 2, 2023 -- This year’s Nobel Prize for physiology or medicine has been awarded to two scientists who laid the groundwork years ago for the mRNA research that made COVID-19 vaccines possible. Dr. Katalin Karikó, the 13th.
Perficient: Drug Development
OCTOBER 3, 2023
In this blog, we will be discussing Schema.org, the role of schema.org in SEO, and how to implement Schema.org in Sitecore. What is Schema.org? Schema.org is a universal way to describe web pages with structured data. Search engines use this information to enrich the user experience on their search results and generate rich snippets. Structured data can impact Organic impressions, CTR, and keyword ranking.
KIF1A
SEPTEMBER 30, 2023
#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research In the rare disease space, a common and straightforward question is: How rare is the disease?
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
addgene Blog
OCTOBER 3, 2023
In April 2022, physicians in Scotland began noticing unusual cases of acute hepatitis in the pediatric population. Once ~400 cases had amassed in places around the world, hypotheses began to develop that this illness was caused by either SARS-CoV-2, Adenovirus type 41 (AdV-41), or Adenovirus-Associated Virus type 2 (AAV2) – or some unprecedented combination of the three (Servellita et al., 2023).
Drugs.com
SEPTEMBER 30, 2023
FRIDAY, Sept. 29, 2023 -- Faced with growing reports of inaccurate clinical lab tests, the U.S. Food and Drug Administration on Friday announced that it will for the first time regulate these vital diagnostic tools. Many Americans might have.
BioPharma Drive: Drug Pricing
OCTOBER 5, 2023
Kyowa will pay nearly $400 million to acquire Orchard, which sells the gene therapy Libmeldy in Europe but has struggled to find paths to market for other experimental treatments.
Drug Target Review
OCTOBER 2, 2023
Immunopeptidomics is a rapidly expanding field at the intersection of immunology and proteomics that focuses on the identification and characterization of peptides presented by major histocompatibility complex (MHC) molecules, also known as the human leukocyte antigen (HLA), on cell surfaces. These peptides are a vital part of the immune system’s display-recognition mechanism that enables T cells to distinguish between self and non-self-antigens, recognizing intruders to initiate immune response
Science Daily: Pharmacology News
OCTOBER 3, 2023
Researchers developed the first AI to date that can intelligently design robots from scratch by compressing billions of years of evolution into mere seconds. It's not only fast but also runs on a lightweight computer and designs wholly novel structures from scratch — without human-labeled, bias-filled datasets.
Drugs.com
SEPTEMBER 30, 2023
FRIDAY, Sept. 29, 2023 – When pregnant women get a COVID vaccine, it helps protect their newborns from the virus, a new government study shows. "These findings indicate that maternal vaccination during pregnancy could help prevent.
biobide
OCTOBER 6, 2023
Pesticides are an essential resource in ensuring sustainable farming and food production around the world. Even organic farming makes use of pesticides, albeit from natural sources, to reduce losses and increase crop yield. The aim here is not only to prevent plants from being eaten or damaged by pests and weeds but to prevent crops from being contaminated with substances that may be harmful to consumers.
Drug Target Review
OCTOBER 3, 2023
A collaboration between the University of North Carolina’s Department of Surgery, the Joint UNC-NCSU Department of Biomedical Engineering, and the UNC Lineberger Comprehensive Cancer Center has given birth to an AI model capable of determining whether cancerous tissue has been completely excised during breast cancer surgery. Their remarkable findings were recently published in the prestigious Annals of Surgical Oncology.
Science Daily: Pharmacology News
OCTOBER 4, 2023
New research has overturned the traditional view that natural rock weathering acts as a carbon sink that removes CO2 from the atmosphere. Instead, this can also act as a large CO2 source, rivaling that of volcanoes.
Drugs.com
OCTOBER 6, 2023
THURSDAY, Oct. 5, 2023 -- America's kids are safer now than a decade ago when it comes to many types of injury, with two glaring exceptions: drugs and guns. That's the crux of a new study that looked at injury trends among U.S. children and.
addgene Blog
OCTOBER 5, 2023
In a world where so much is out of your hands, it’s helpful to focus on something controllable, like experiments (and their controls!). This blog post will discuss the ins and outs of controls for biological experiments, starting with general controls and then moving on to controls for antibody-related applications. After reading, you will have a better understanding of the different types of controls and be able to use this information to design thoughtfully and thoroughly controlled experiment
BioPharma Drive: Drug Pricing
OCTOBER 3, 2023
The deal will hand Lilly a pipeline of experimental radioligand therapies, including a potential rival to Novartis’ Pluvicto, as well as a valuable manufacturing plant.
Science Daily: Pharmacology News
OCTOBER 4, 2023
Researchers have produced an engineered tissue representing a simplified cerebral cortex by 3D printing human stem cells. When implanted into mouse brain slices, the structures became integrated with the host tissue. The technique may ultimately be developed into tailored repairs to treat brain injuries.
Drugs.com
OCTOBER 2, 2023
MONDAY, Oct. 2, 2023 -- New research shows the COVID-19 virus can directly infect coronary arteries, inflaming fatty plaque inside them, which can increase the risk of heart disease and stroke. This may explain why some people who get COVID-19 have.
PLOS: DNA Science
OCTOBER 5, 2023
In recognition of Breast Cancer Awareness month , I am republishing this essay written on the eve of the pandemic. It’s an intriguing perspective: in a matter of weeks, everyone worried about survival, not just those of us with cancer and other life-threatening or altering conditions. I’m happy to report that all of us who have faced breast cancer are doing well!
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