Science Daily: Pharmacology News
MAY 18, 2023
Fifty-three percent of the world's largest freshwater lakes are in decline, storing less water than they did three decades ago, according to a new study. The study analyzed satellite observations dating back decades to measure changes in water levels in nearly 2,000 of the world's biggest lakes and reservoirs. It found that climate change, human consumption and sedimentation are responsible.
Forbes: Drug Truths
MAY 15, 2023
In the midst of the Covid-19 pandemic, when thousands of people were dying on a daily basis, the hopes of the world rested on the biopharmaceutical industry for rapidly finding vaccines, antibodies and therapeutants.
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Drug Hunter
MAY 18, 2023
Dian Su’s journey from chemistry and proteomics to the DMPK of drug conjugates Following a different path comes naturally to Dian Su, Senior Director of DMPK at Bicycle Therapeutics. From a childhood in a small village in China’s northeast Shandong province to her work examining the drug metabolism and pharmacokinetics (DMPK) of antibody-drug conjugates (ADCs) and Bicycle toxin conjugates ® (BTCs), Dian has always looked to forge something new.
Drug Patent Watch
MAY 16, 2023
On NPR’s All Things Considered, Sydney Lupkin asked DrugPatentWatch if drug patents could be used to identify injector pens which could then be swapped to fix drug shortages. Referring to… The post NPR and DrugPatentWatch – Can drug injector pens be swapped? appeared first on DrugPatentWatch - Make Better Decisions.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Science Daily: Pharmacology News
MAY 19, 2023
An international team of researchers identifies engravings in Jordan and Saudi Arabia as the oldest known building plans to The archaeological finds are 8,000 to 9,000 years old and depict nearby desert dragons -- huge prehistoric megastructures used. The findings will help us understand how desert dragons were conceived and built.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
ASPET
MAY 15, 2023
Nitrogen mustard (NM) is a cytotoxic vesicant known that causes pulmonary injury that can progress to fibrosis. NM toxicity is associated with an influx of inflammatory macrophages in the lung. Farnesoid X Receptor (FXR) is a nuclear receptor involved in bile acid and lipid homeostasis that has anti-inflammatory activity. In these studies, we analyzed the effects of FXR activation on lung injury, oxidative stress and fibrosis induced by NM.
Covalent Modifiers
MAY 15, 2023
Bin Zhang, Chengchen Zhu, Albert S.C. Chan, Gui Lu European Journal of Medicinal Chemistry , 2023 [link] Aurora kinases, which belong to the serine/threonine protein family, play critical roles in the regulation of the cell cycle and mitotic spindle assembly. They are frequently highly expressed in various types of tumors, and the use of selective Aurora kinase inhibitors has become a potential treatment option for cancer therapy.
Science Daily: Pharmacology News
MAY 18, 2023
Evolution is a sequence of design changes happening on their own in a discernible direction; it never weds itself to a single point on a drawing board. An evolving system or animal is free to simply go with what works. Not so much that its performance suffers greatly, but enough that it opens access to other options near the so-called optimal design.
Drug Discovery Today
MAY 19, 2023
Sciad Newswire / Connect in Pharma announce today that for every visitor to the 2023 Geneva-based event, five Swiss francs will be donated to Global Health Security (GHS) Fund, a non-profit organisation driving local innovation and global programming to address threats to health security.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drug Policy Alliance
MAY 19, 2023
St. Paul, MN – May 18, 2023 – Today, Governor Tim Walz signed Senate File 2909, the House Omnibus Judiciary and Public Safety Finance bill. In addition to expanding access to harm reduction services, including drug checking services, this bill will make giving away and possessing all drug paraphernalia, as well as any contained residue, legal.
Antidote
MAY 18, 2023
Clinical Trials Day takes place on May 20 each year, and is a day to celebrate the thousands of medical research volunteers who participate in trials for a wide range of conditions. It's also a day to raise awareness of the fact that even more volunteers are needed to push medical research forward.
Science Daily: Pharmacology News
MAY 18, 2023
Researchers report that the financial toll of the climate pattern known as El Niño can persist for several years and cost trillions in lost income worldwide. The study, which is among the first to evaluate the long-term costs of El Niño, found that the 1982 and 1997 events led to $4.1 trillion and $5.7 trillion in lost income in the five years following them.
Drug Patent Watch
MAY 13, 2023
Annual Drug Patent Expirations for BANZEL Banzel is a drug marketed by Eisai Inc and is included in two NDAs. It is available from one supplier. There is one patent… The post New patent expiration for Eisai Inc drug BANZEL appeared first on DrugPatentWatch - Make Better Decisions.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Channels
MAY 16, 2023
Last August , I warned you about alternative funding programs (AFPs) –the shady schemes by which commercial plan sponsors drop drug coverage in order to grab charity support intended for uninsured and indigent patients. I’m sad to report that the manipulation of charitable patient assistance programs continues to expand. As you will see below, employers have significantly ramped up their adoption of AFPs, while health plans seem more skeptical.
ProRelix Research
MAY 15, 2023
Clinical Research Organizations (CROs) are companies that provide support to the pharmaceutical and biotech industries by managing various aspects of the drug development process and conducting clinical trials. In this […] The post Clinical Research Organizations: Importance, Services, Selection Process and Future. appeared first on ProRelix Research.
Science Daily: Pharmacology News
MAY 19, 2023
In nature, the skin of cephalopods (animals with tentacles attached to the head) exhibits unparalleled camouflage ability. Their skin contains pigment groups that can sense changes in environmental light conditions and adjust their appearance through the action of pigment cells. Although intricate in nature, this colour-changing ability is fundamentally based on a mechanical mechanism in which pigment particles are folded or unfolded under the control of radial muscles.
Drug Patent Watch
MAY 15, 2023
Annual Drug Patent Expirations for EXFORGE+HCT Exforge Hct is a drug marketed by Novartis and is included in one NDA. It is available from one supplier. There are two patents… The post New patent expiration for Novartis drug EXFORGE HCT appeared first on DrugPatentWatch - Make Better Decisions.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drug Channels
MAY 18, 2023
Today’s guest post comes from Patrick Leary, Chief Commercial Officer at Phil, Inc. Patrick describes how barriers to medication access affect manufacturers and patients. He offers four tactics that can help field teams unlock coverage for patients. To learn more about Phil’s access and commercialization solutions, download their free whitepaper, Modernize the Patient Access Experience: Transform Your Pharmaceutical Brand.
PLOS: DNA Science
MAY 18, 2023
When a dear friend recommended The Love Songs of W. E. B. Du Bois , I thought the book was a tribute to the famous Black historian, sociologist, scholar, and civil rights activist. Although excerpts of his writings open chapters, the book is sweeping historical fiction – perhaps the best I’ve ever read. The Love Songs of W. E. B. Du Bois , the first novel by award-winning poet Honoree Fanonne Jeffers, traces an American Black family back eight generations, through the eyes of Ailey P
Science Daily: Pharmacology News
MAY 19, 2023
Researchers have observed the X-ray emission of the most luminous quasar seen in the last 9 billion years of cosmic history, known as SMSS J114447.77-430859.3, or J1144 for short. The new perspective sheds light on the inner workings of quasars and how they interact with their environment.
Drug Patent Watch
MAY 15, 2023
This chart shows the pharmaceutical companies with the most patents in Philippines. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is… The post Which pharmaceutical companies have the most drug patents in Philippines? appeared first on DrugPatentWatch - Make Better Decisions.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
biobide
MAY 18, 2023
There are different relevant animal models which are used in research, being rodents the most common model in use. However, zebrafish have traditionally been the one of choice when it comes to studying the developmental stages of vertebrates. There are key features supporting the use of zebrafish research for these studies, including the external development of the embryos, their transparency, their throughput, and the similarity of their organs to mammals.
PPD
MAY 18, 2023
For neurodegenerative disease research, the care partner, or caregiver, is equally important as the person with dementia. The care partners are the decision-makers for their loved ones with neurodegenerative disorders, handling everything from daily routines and medication management to doctor visits. Yet, four out of five care partners of people with neurodegenerative disorders have never been informed of clinical trial opportunities , according to a survey of more than 250 caregivers conducted
Science Daily: Pharmacology News
MAY 18, 2023
The number of qubits in superconducting quantum computers has risen rapidly during the last years, but further growth is limited by the need for ultra-cold operating temperatures. Connecting several smaller processors could create larger, more computationally powerful quantum computers -- however doing so poses new challenges. Researchers have now demonstrated quantum entanglement between optical and microwave photons that could lay the foundation for such a future quantum network.
Drug Target Review
MAY 18, 2023
Results of the Multicenter Study of Hydroxyurea in Sickle Cell Anaemia published in the Journal of the American Medical Association in 2003, indicated that the use of hydroxyurea, the only drug approved at the time, reduced mortality as it reduced pain crises and increased foetal haemoglobin. Foetal haemoglobin (HbF) is the predominant type of haemoglobin (Hb) in foetal life and remains so until just before birth when its production is turned down while the production of adult Hb is turned up
biobide
MAY 18, 2023
Numerous experimental models currently used in the preclinical arena can aid the research and development of new pharmaceutical compounds and Drug Discovery. These experimental models may range from basic high throughput computational models to more biologically significant animal models but all of them are conceived to better predict the behavior of a particular drug before interacting with the human body.
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