Sat.Aug 24, 2024 - Fri.Aug 30, 2024

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Cell and gene therapy investment, once booming, is now in a slump

BioPharma Drive: Drug Pricing

Far fewer venture funding rounds were closed by cell and gene therapy developers over the first six months of 2024 than in prior years. Experts say there are several factors.

Therapies 142
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Brain research: Study shows what your favorite film genres reveal about your brain

Science Daily: Pharmacology News

Crime films, action films, comedies, or documentaries? A person's favorite film genre reveals a lot about how their brain works. Fans of action films and comedies reacted very strongly to negative emotional stimuli, while participants who favored documentaries or crime films and thrillers had a significantly weaker reaction.

Research 133
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Older Black Men Are Disproportionately Affected by the Overdose Crisis

National Institute on Drug Abuse: Nora's Blog

Older Black Men Are Disproportionately Affected by the Overdose Crisis mfleming Wed, 08/28/2024 - 16:08 Nora's Blog August 30, 2024 Image ©Getty Images/ xavierarnau Saturday, August 31, is International Overdose Awareness Day , when we collectively remember those who have lost their lives to drug overdose, support those who grieve those losses, and offer encouragement to those who seek recovery from addiction.

Treatment 117
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Ozempic, Wegovy Have Health Benefits Beyond Weight Loss, Studies Find

Drugs.com

FRIDAY, Aug.30, 2024 -- New trials are showing how the blockbuster diabetes and weight-loss meds Ozempic and Wegovy can boost health in even more ways.These two injected drugs are versions of semaglutide. In multiple new data analyses, the drugs.

Trials 119
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Macrophage cell therapy: a new hope for chronic liver disease patients

Drug Target Review

What are the main challenges currently faced in the treatment of chronic liver diseases, and how does Resolution Therapeutics aim to address these challenges? Once a patient develops advanced cirrhosis/end-stage liver disease there are no specific therapies to significantly avoid major decompensations and death in the next few years. This is caused by the high amounts of inflammation and fibrosis (scarring) in the liver, suppressing the liver’s natural ability to regenerate or perform its functi

Therapies 114
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Neuroscientists explore the intersection of music and memory

Science Daily: Pharmacology News

New research explores music's impact on learning, memory, and emotions in two studies. One reveals that familiar music can enhance concentration and learning, while the other demonstrates that music with a strong emotional tone can reshape the quality of existing memories. These findings suggest that music could be used for therapeutic interventions for cognitive function, or in conditions like PTSD and depression.

Research 122

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Antibiotic Overuse in Nursing Homes Could Foster 'Superbugs'

Drugs.com

FRIDAY, Aug. 30, 2024 -- Senior residential homes are breeding grounds for antibiotic-resistant bacteria, due to overprescription of antibiotics, a new study says.Stool samples provided by Australian senior home residents contained bacteria with a.

Nurses 115
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Lilly rolls out Zepbound vials at a discount price

BioPharma Drive: Drug Pricing

The launch of a single-use vial form of the popular weight loss medicine could help Lilly improve supply and compete with telehealth companies offering compounded versions.

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Matching dinosaur footprints found on opposite sides of the Atlantic Ocean

Science Daily: Pharmacology News

An international team of paleontologists has found matching sets of Early Cretaceous dinosaur footprints on what are now two different continents.

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Sandbagging & Lowballing : Project Estimating (Part 1)

Perficient: Drug Development

This post is the first in a series of four about estimating project hours. Part 1: Sandbagging & Lowballing Coming Soon: Part 2: Dependencies & Creep Part 3: Assumptions & Uncertainty Part 4: The Emotional Conclusion Estimating is a precarious business – part science, a lot of guesswork, and a bit of psychic magic! The goal is to forecast the effort, time, and cost of a project with enough accuracy to avoid disaster.

Science 110
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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First Cluster of Cases of Human Bird Flu Detected at Colorado Poultry Facilities

Drugs.com

THURSDAY, Aug. 29, 2024 (HeathDay News) -- The first known U.S. cluster of cases of bird flu in humans has been recorded at two poultry facilities in Colorado, the Centers for Disease Control and Prevention (CDC) reported Thursday.The nine infected.

Disease 116
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Bayer partners with RNA drugmaker to develop new cancer therapies

BioPharma Drive: Drug Pricing

Under a collaboration with NextRNA Therapeutics, Bayer will access the biotech’s platform to target long, non-coding RNA interactions with small molecule drugs.

RNA 114
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Morphing facial technology sheds light on the boundaries of self-recognition

Science Daily: Pharmacology News

Facial recognition is a critical part of self-image and social interactions. In an era of advanced digital technology, we face intriguing questions about communication and identity. How does altering our facial identity affect our sense of 'self' and our interactions with others?

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A Reflection on Perficient’s Employee Resource Groups (ERGs): Building Space for Our Colleagues

Perficient: Drug Development

Perficient continues to make strategic investments to grow our global footprint. This is great for our clients because we span time zones, cultures and capabilities. However, it can present a challenge fostering a cohesive company culture and opportunities for colleagues to connect. That is why Perficient invests in its people by supporting Employee Resource Groups (ERGs), Special Interest Groups (SIGs), and Innovation Groups (IGs).

Marketing 104
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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An Alzheimer's Drug May Also Slow Lewy Body Dementia

Drugs.com

MONDAY, Aug. 24, 2024 -- A type of drug used to treat Alzheimer’s disease appears to slow the progression of Lewy body dementia, the brain disease that afflicted comedian Robin Williams prior to his suicide.Cholinesterase inhibitors prevent the b.

Drugs 116
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Pfizer launches DTC service for migraine, COVID drugs

BioPharma Drive: Drug Pricing

The platform is similar in concept to a service launched this year by Eli Lilly, and aims to give consumers easier access to Pfizer’s migraine, COVID-19 and flu treatments.

Treatment 109
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New process vaporizes plastic bags and bottles, yielding gases to make new, recycled plastics

Science Daily: Pharmacology News

Chemists have developed a catalytic process that turns the largest component of today's plastic waste stream, polyolefin plastic bags and bottles, into gases -- propylene and isobutylene -- that are the building blocks of polypropylene and other types of plastics. The process uses inexpensive solid catalysts that can be scaled to industrial production, making this a potentially viable means of creating a circular economy for these throw-away plastics.

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DEA To Announce Hearing on Proposed Marijuana Rescheduling

FDA Law Blog: Biosimilars

By Larry K. Houck — Who says nothing happens in Washington, D.C., in August? The Drug Enforcement Administration (“DEA”) will announce Thursday in the Federal Register that it will hold a hearing on the proposed rescheduling of marijuana to schedule III at DEA Headquarters in Arlington, Virginia on December 2, 2024. DEA received over 43,500 public comments in response to the agency’s Notice of Proposed Rulemaking in the Federal Register on May 21, 2024.

Drugs 103
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Migraine Drug Ubrelvy May Stop Headaches Before They Start

Drugs.com

THURSDAY, Aug. 29, 2024 -- A migraine drug can help stop the devastating headaches in their tracks, allowing sufferers to go about their daily lives with little to no symptoms, a new clinical trial has found.People who took ubrogepant (Ubrelvy).

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Neurocrine’s mixed schizophrenia data disappoint Wall Street

BioPharma Drive: Drug Pricing

Despite “positive” results, shares of the biotech slid by 20%. Analysts cautioned that Neurocrine shouldn’t get “the benefit of the doubt” with its data.

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New study supports annual breast cancer screening for women over 40

Science Daily: Pharmacology News

Women diagnosed with breast cancer who had regular screening mammograms every year were less likely to have late-stage cancer and had higher overall survival than those who received screening every other year or less often, according to new research.

Research 117
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How the Proper Product Information Management (PIM) System Can Boost Sales During the Holiday Season

Perficient: Drug Development

For most businesses, the holiday season is a critical time that often accounts for a significant portion of annual sales. To properly capitalize on this opportunity, companies must ensure their product information is accurate, consistent, and compelling across all channels. This is where Product Information Management (PIM) systems come into play.

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Buying Smokes? Everyone Under 30 Now Must Show ID

Drugs.com

FRIDAY, Aug. 30, 2024 -- A new, tougher rule on the sale of tobacco products will require retailers to check the IDs of any buyers under the age of 30, the U.S. Food and Drug Administration announced Thursday.The final rule, which will go into.

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Keytruda fails lung and skin cancer trials, limiting further expansion

BioPharma Drive: Drug Pricing

The trial setbacks for Merck’s best-selling drug, which faces patent expiration in 2028, are a blow to the company’s plans for further indication expansion.

Trials 107
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Bats are surviving and thriving on nothing but sugar

Science Daily: Pharmacology News

New research may enable potential solutions to metabolic disease by turning to evolution and to bats. 'Our study reports blood sugar levels that are the highest we have ever seen in nature -- what would be lethal, coma-inducing levels for mammals, but not for bats,' said one of the researchers. 'We are seeing a new trait we didn't know was possible.

Disease 116
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Nationwide to Talk Personalization, Data, and AI at Dreamforce 2024

Perficient: Drug Development

Next-level personalization strategies will undoubtedly be a key topic at Salesforce’s largest event this year. Dreamforce is right around the corner taking place in San Francisco on September 17 to 19, and learning how to get the most out of your customer data with AI-powered tools is top of mind. Whether you’re attending in person or virtually, the conference boasts numerous opportunities to hear how some of the world’s largest brands are using data and AI to create personalized journeys and pr

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Unexpected Medical Bill? Challenging It Often Brings Results, Study Finds

Drugs.com

FRIDAY, Aug. 30, 2024 -- People who challenge an unexpected medical bill often get some form of financial relief, a new study says.About 1 in 5 people say they’ve recently received a medical bill they disagreed with or couldn’t afford to pay, acc.

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Tome Biosciences to lay off over 100 employees

BioPharma Drive: Drug Pricing

The buzzy startup, which had raised over $200 million in venture funding, is letting go of much of its workforce, according to a state regulatory notice.

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Bacterial cells transmit memories to offspring

Science Daily: Pharmacology News

Bacterial cells can 'remember' brief, temporary changes to their bodies and immediate surroundings, a new study has found. And, although these changes are not encoded in the cell's genetics, the cell still passes memories of them to its offspring -- for multiple generations.

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NVIDIA Launches NIM Agent Blueprints for Generative AI

Nvidia Developer: Drug Discovery

Now available—NIM Agent Blueprints for digital humans, multimodal PDF data extraction, and drug discovery. Now available—NIM Agent Blueprints for digital humans, multimodal PDF data extraction, and drug discovery.

Drugs 98
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Depression Might Sometimes Be Early Sign of Alzheimer's Disease

Drugs.com

FRIDAY, Aug. 30, 2024 -- In some people, new-onset depression may stem from the same buildup of toxic plaques in the brain that have long been linked to Alzheimer's disease, according to a new study."Our findings provide additional support for.

Disease 105
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PBM executives threatened with fines for alleged perjury in House hearing

BioPharma Drive: Drug Pricing

Testimony from the heads of Express Scripts, Optum Rx and Caremark in July defending pharmacy benefit managers’ business practices could be coming back to bite them.

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Scientist's method could give months' warning of major earthquakes

Science Daily: Pharmacology News

The public could have days or months of warning about a major earthquake through identification of prior low-level tectonic unrest over large areas, according to research by scientists who analyzed two major quakes in Alaska and California.

Research 113