Sat.Aug 24, 2024 - Fri.Aug 30, 2024

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Cell and gene therapy investment, once booming, is now in a slump

BioPharma Drive: Drug Pricing

Far fewer venture funding rounds were closed by cell and gene therapy developers over the first six months of 2024 than in prior years. Experts say there are several factors.

Therapies 356
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Brain research: Study shows what your favorite film genres reveal about your brain

Science Daily: Pharmacology News

Crime films, action films, comedies, or documentaries? A person's favorite film genre reveals a lot about how their brain works. Fans of action films and comedies reacted very strongly to negative emotional stimuli, while participants who favored documentaries or crime films and thrillers had a significantly weaker reaction.

Research 337
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Ozempic, Wegovy Have Health Benefits Beyond Weight Loss, Studies Find

Drugs.com

FRIDAY, Aug.30, 2024 -- New trials are showing how the blockbuster diabetes and weight-loss meds Ozempic and Wegovy can boost health in even more ways.These two injected drugs are versions of semaglutide. In multiple new data analyses, the drugs.

Trials 299
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Nanome and Collaborative Drug Discovery (CDD) Announce Partnership That Streamlines Cheminformatic Workflows for Drug Discovery

Collaborative Drug

Nanome and Collaborative Drug Discovery (CDD) are excited to announce a partnership that streamlines cheminformatic workflows for drug discovery Together, Nanome and Collaborative Drug Discovery (CDD) are committed to enhancing the efficiency and innovation of drug discovery teams by providing an integrated solution for molecular visualization, design, and data analysis.

Drugs 246
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Lilly rolls out Zepbound vials at a discount price

BioPharma Drive: Drug Pricing

The launch of a single-use vial form of the popular weight loss medicine could help Lilly improve supply and compete with telehealth companies offering compounded versions.

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More Trending

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Antibiotic Overuse in Nursing Homes Could Foster 'Superbugs'

Drugs.com

FRIDAY, Aug. 30, 2024 -- Senior residential homes are breeding grounds for antibiotic-resistant bacteria, due to overprescription of antibiotics, a new study says.Stool samples provided by Australian senior home residents contained bacteria with a.

Nurses 289
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Aminomethyl Salicylaldehydes Lock onto a Surface Lysine by Forming an Extended Intramolecular Hydrogen Bond Network

Covalent Modifiers

Jacqueline Weaver, Gregory B. Craven, Linh Tram, Hao Chen, and Jack Taunton Journal of the American Chemical Society 2024 DOI: 10.1021/jacs.4c04314 The development of electrophilic ligands that rapidly modify specific lysine residues remains a major challenge. Salicylaldehyde-based inhibitors have been reported to form stable imine adducts with the catalytic lysine of protein kinases.

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Bayer partners with RNA drugmaker to develop new cancer therapies

BioPharma Drive: Drug Pricing

Under a collaboration with NextRNA Therapeutics, Bayer will access the biotech’s platform to target long, non-coding RNA interactions with small molecule drugs.

RNA 280
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Neuroscientists explore the intersection of music and memory

Science Daily: Pharmacology News

New research explores music's impact on learning, memory, and emotions in two studies. One reveals that familiar music can enhance concentration and learning, while the other demonstrates that music with a strong emotional tone can reshape the quality of existing memories. These findings suggest that music could be used for therapeutic interventions for cognitive function, or in conditions like PTSD and depression.

Research 330
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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First Cluster of Cases of Human Bird Flu Detected at Colorado Poultry Facilities

Drugs.com

THURSDAY, Aug. 29, 2024 (HeathDay News) -- The first known U.S. cluster of cases of bird flu in humans has been recorded at two poultry facilities in Colorado, the Centers for Disease Control and Prevention (CDC) reported Thursday.The nine infected.

Disease 290
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Macrophage cell therapy: a new hope for chronic liver disease patients

Drug Target Review

What are the main challenges currently faced in the treatment of chronic liver diseases, and how does Resolution Therapeutics aim to address these challenges? Once a patient develops advanced cirrhosis/end-stage liver disease there are no specific therapies to significantly avoid major decompensations and death in the next few years. This is caused by the high amounts of inflammation and fibrosis (scarring) in the liver, suppressing the liver’s natural ability to regenerate or perform its functi

Therapies 116
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Tome Biosciences to lay off over 100 employees

BioPharma Drive: Drug Pricing

The buzzy startup, which had raised over $200 million in venture funding, is letting go of much of its workforce, according to a state regulatory notice.

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Morphing facial technology sheds light on the boundaries of self-recognition

Science Daily: Pharmacology News

Facial recognition is a critical part of self-image and social interactions. In an era of advanced digital technology, we face intriguing questions about communication and identity. How does altering our facial identity affect our sense of 'self' and our interactions with others?

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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An Alzheimer's Drug May Also Slow Lewy Body Dementia

Drugs.com

MONDAY, Aug. 24, 2024 -- A type of drug used to treat Alzheimer’s disease appears to slow the progression of Lewy body dementia, the brain disease that afflicted comedian Robin Williams prior to his suicide.Cholinesterase inhibitors prevent the b.

Drugs 290
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Older Black Men Are Disproportionately Affected by the Overdose Crisis

National Institute on Drug Abuse: Nora's Blog

Older Black Men Are Disproportionately Affected by the Overdose Crisis mfleming Wed, 08/28/2024 - 16:08 Nora's Blog August 30, 2024 Image ©Getty Images/ xavierarnau Saturday, August 31, is International Overdose Awareness Day , when we collectively remember those who have lost their lives to drug overdose, support those who grieve those losses, and offer encouragement to those who seek recovery from addiction.

Treatment 110
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Neurocrine’s mixed schizophrenia data disappoint Wall Street

BioPharma Drive: Drug Pricing

Despite “positive” results, shares of the biotech slid by 20%. Analysts cautioned that Neurocrine shouldn’t get “the benefit of the doubt” with its data.

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Bats are surviving and thriving on nothing but sugar

Science Daily: Pharmacology News

New research may enable potential solutions to metabolic disease by turning to evolution and to bats. 'Our study reports blood sugar levels that are the highest we have ever seen in nature -- what would be lethal, coma-inducing levels for mammals, but not for bats,' said one of the researchers. 'We are seeing a new trait we didn't know was possible.

Disease 315
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Unexpected Medical Bill? Challenging It Often Brings Results, Study Finds

Drugs.com

FRIDAY, Aug. 30, 2024 -- People who challenge an unexpected medical bill often get some form of financial relief, a new study says.About 1 in 5 people say they’ve recently received a medical bill they disagreed with or couldn’t afford to pay, acc.

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Sandbagging & Lowballing : Project Estimating (Part 1)

Perficient: Drug Development

This post is the first in a series of four about estimating project hours. Part 1: Sandbagging & Lowballing Coming Soon: Part 2: Dependencies & Creep Part 3: Assumptions & Uncertainty Part 4: The Emotional Conclusion Estimating is a precarious business – part science, a lot of guesswork, and a bit of psychic magic! The goal is to forecast the effort, time, and cost of a project with enough accuracy to avoid disaster.

Science 110
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Pfizer launches DTC service for migraine, COVID drugs

BioPharma Drive: Drug Pricing

The platform is similar in concept to a service launched this year by Eli Lilly, and aims to give consumers easier access to Pfizer’s migraine, COVID-19 and flu treatments.

Treatment 267
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Scientists discover how starfish get 'legless'

Science Daily: Pharmacology News

Researchers have made a groundbreaking discovery about how sea stars (commonly known as starfish) manage to survive predatory attacks by shedding their own limbs. The team has identified a neurohormone responsible for triggering this remarkable feat of self-preservation.

Research 314
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Migraine Drug Ubrelvy May Stop Headaches Before They Start

Drugs.com

THURSDAY, Aug. 29, 2024 -- A migraine drug can help stop the devastating headaches in their tracks, allowing sufferers to go about their daily lives with little to no symptoms, a new clinical trial has found.People who took ubrogepant (Ubrelvy).

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Labor Day Message 2024

NIOSH Science Blog: Drugs

Each Labor Day we honor workers and the role they play in building a strong and prosperous nation. Much like the first Labor Day more than a century ago, many of us mark this federal holiday with festivities such as parades or picnics. This year, as you head out to celebrate the end of summer with friends and loved ones, I urge you to take a moment to reflect on the contributions of the workers all around us.

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Keytruda fails lung and skin cancer trials, limiting further expansion

BioPharma Drive: Drug Pricing

The trial setbacks for Merck’s best-selling drug, which faces patent expiration in 2028, are a blow to the company’s plans for further indication expansion.

Trials 265
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Genomic dark matter solves butterfly evolutionary riddle

Science Daily: Pharmacology News

Researchers have uncovered a surprising genetic mechanism that influences the vibrant and complex patterns on butterfly wings. The team discovered that an RNA molecule, rather than a protein as previously thought, plays a pivotal role in determining the distribution of black pigment on butterfly wings.

RNA 312
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Buying Smokes? Everyone Under 30 Now Must Show ID

Drugs.com

FRIDAY, Aug. 30, 2024 -- A new, tougher rule on the sale of tobacco products will require retailers to check the IDs of any buyers under the age of 30, the U.S. Food and Drug Administration announced Thursday.The final rule, which will go into.