Science Daily: Pharmacology News
FEBRUARY 15, 2024
Our brains are 'programmed' to learn more from people we like -- and less from those we dislike. This has been shown by researchers in cognitive neuroscience in a series of experiments.
DrugBaron
FEBRUARY 16, 2024
“There is more than one way to skin a cat” is a rather gruesome British idiom, but its sentiment surely applies to running a successful pharmaceutical portfolio. It is now more than a decade since Francesco De Rubertis, together with Kevin Johnson and Michele Olier, coined the term “asset-centric” investing to describe the approach to portfolio creation that still underpins the strategy at Medicxi.
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BioPharma Drive: Drug Pricing
FEBRUARY 15, 2024
Analysts pressed Alnylam executives on the reasons for the changes to HELIOS-B, a Phase 3 study in ATTR amyloidosis with cardiomyopathy that is important to the company’s future.
Drugs.com
FEBRUARY 14, 2024
WEDNESDAY, Feb. 14, 2024 -- An Oregonian who was diagnosed with the bubonic plague -- the disease that killed millions of Europeans in the Middle Ages -- probably got it from an infected pet cat, health officials said. The patient and all close.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Science Daily: Pharmacology News
FEBRUARY 12, 2024
You can mend a broken heart this valentine s day now that researchers invented a new hydrogel that can be used to heal damaged heart tissue and improve cancer treatments.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
FEBRUARY 14, 2024
The company and partner Biogen say signs from payers and doctors suggest the launch of Zurzuvae, the first oral therapy for PPD, is off to a good start.
Drugs.com
FEBRUARY 13, 2024
TUESDAY, Feb. 13, 2024 -- Mammograms are a lifesaving misery for middle-aged women, but a new tool could make getting a breast cancer screening as easy as spitting.Literally.A new hand-held biosensor can detect breast cancer biomarkers from a tiny.
Science Daily: Pharmacology News
FEBRUARY 13, 2024
Smelling a familiar scent can help depressed individuals recall specific autobiographical memories and potentially assist in their recovery.
Chemical Biology and Drug Design
FEBRUARY 15, 2024
Role of serotonin, dopamine, and norepinephrine in neural functions and symptoms involved during their altered levels. Abstract Depression is not similar to daily mood fluctuations and temporary emotional responses to day-to-day activities. Depression is not a passing problem; it is an ongoing problem. It deals with different episodes consisting of several symptoms that last for at least 2 weeks.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
BioPharma Drive: Drug Pricing
FEBRUARY 14, 2024
Latigo Biotherapeutics has raised $135 million to develop drugs that block NaV1.8, a target shared by a Vertex therapy that just succeeded in Phase 3 testing.
Drugs.com
FEBRUARY 16, 2024
FRIDAY, Feb. 16, 2024 (HealthDay news) -- A drug first developed to treat cocaine addiction might also help slow the spread of advanced colon cancer, a new study suggests.The drug vanoxerine appears to suppress cancer stem cell activity by.
Science Daily: Pharmacology News
FEBRUARY 12, 2024
Growing cartilage tissue in the lab could help patiens with injuries, but it is very hard to make the tissue grow in exactly the right shape. A new approach could solve this problem: Tiny spherical containers are created with a high-resolution 3D printer. These containers are then filled with cells and assembled into the desired shape. The cells from different containers connect, the container itself is degradable and eventually disappears.
Covalent Modifiers
FEBRUARY 16, 2024
Sarath Ramachandran, Nikolai Makukhin, Kevin Haubrich, Manjula Nagala, Beth Forrester, Dylan M. Lynch, Ryan Casement, Andrea Testa, Elvira Bruno, Rosaria Gitto & Alessio Ciulli Nat Commun 14 , 6345 (2023). [link] The Src homology 2 (SH2) domain recognizes phosphotyrosine (pY) post translational modifications in partner proteins to trigger downstream signaling.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioPharma Drive: Drug Pricing
FEBRUARY 16, 2024
The disclosure the experimental therapy missed its trial goal comes after Sanofi had earmarked the drug for advancement into Phase 3.
Drugs.com
FEBRUARY 16, 2024
FRIDAY, Feb. 16, 2024 -- The U.S. Centers for Disease Control and Prevention is weighing whether to recommend another COVID booster shot this spring, most likely for those who are vulnerable to severe illness.An advisory panel to the CDC is.
Science Daily: Pharmacology News
FEBRUARY 16, 2024
A research team that had previously succeeded in synthesizing fumaric acid using bicarbonate and pyruvic acid, and carbon dioxide collected directly from the gas phase as one of the raw materials, has now created a new photosensitizer and developed a new artificial photosynthesis technology, effectively doubling the yield of fumaric acid production compared to the previous method.
Covalent Modifiers
FEBRUARY 15, 2024
Davis H. Chase, Adrian M. Bebenek, Pengju Nie, Saul Jaime-Figueroa, Arseniy Butrin, Danielle A. Castro, John Hines, Brian M. Linhares, Craig M. Crews Angew. Chem. Int. Ed. 2024 , e202316496. [link] Brachyury is an oncogenic transcription factor whose overexpression drives chordoma growth. The downmodulation of brachyury in chordoma cells has demonstrated therapeutic potential, however, as a transcription factor it is classically deemed “undruggable”.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
BioPharma Drive: Drug Pricing
FEBRUARY 16, 2024
Kelonia will receive $40 million upfront through a partnership to develop “off-the-shelf” cell therapies for cancer.
Drugs.com
FEBRUARY 16, 2024
FRIDAY, Feb. 16, 2024 -- A standard blood test can reveal whether a person is at high risk of having a heart attack within six months, a new study shows.Researchers identified dozens of biomarkers in blood linked to the risk of a first heart.
Science Daily: Pharmacology News
FEBRUARY 13, 2024
More time stranded on land means greater risk of starvation for polar bears, a new study indicates. During three summer weeks, 20 polar bears closely observed by scientists tried different strategies to maintain energy reserves, including resting, scavenging and foraging. Yet nearly all of them lost weight rapidly: on average around 1 kilogram, or 2.2 pounds, per day.
Broad Institute
FEBRUARY 16, 2024
Study finds youth-onset diabetes is a genetically distinct form of the disorder By Claire Hendershot February 16, 2024 Breadcrumb Home Study finds youth-onset diabetes is a genetically distinct form of the disorder Researchers suggest diabetes exists in multiple forms on a spectrum of varying genetic factors and symptoms. By Claire Hendershot February 16, 2024 Image by Ricardo Job-Reese, Broad Communications.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
FEBRUARY 12, 2024
Explore how companies are optimizing efficiency, enhancing customer experiences and embracing AI.
Drugs.com
FEBRUARY 16, 2024
FRIDAY, Feb. 16, 2024 -- People threatened by accidental exposure to foods they're allergic to may have a new weapon of defense: On Friday, the U.S. Food and Drug Administration expanded the use of the asthma drug Xolair to help prevent.
Science Daily: Pharmacology News
FEBRUARY 13, 2024
Babies playfully tease others as young as eight months of age. Since language is not required for this behavior, similar kinds of playful teasing might be present in non-human animals. Now cognitive biologists and primatologists have documented playful teasing in four species of great apes. Like joking behavior in humans, ape teasing is provocative, persistent, and includes elements of surprise and play.
Codon
FEBRUARY 13, 2024
Tom Ireland writes about the companies and technologies that are reimagining phage therapy. Read it on our website here. Illustration by David S. Goodsell, RCSB Protein Data Bank and Scripps Research. doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of u
BioPharma Drive: Drug Pricing
FEBRUARY 13, 2024
Newly named partner Anthony Philippakis and managing partner Krishna Yeshwant spoke with BioPharma Dive about biotech’s newfound optimism and their investing “North Star.
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