DrugBaron
FEBRUARY 16, 2024
“There is more than one way to skin a cat” is a rather gruesome British idiom, but its sentiment surely applies to running a successful pharmaceutical portfolio. It is now more than a decade since Francesco De Rubertis, together with Kevin Johnson and Michele Olier, coined the term “asset-centric” investing to describe the approach to portfolio creation that still underpins the strategy at Medicxi.
Chemical Biology and Drug Design
FEBRUARY 15, 2024
Role of serotonin, dopamine, and norepinephrine in neural functions and symptoms involved during their altered levels. Abstract Depression is not similar to daily mood fluctuations and temporary emotional responses to day-to-day activities. Depression is not a passing problem; it is an ongoing problem. It deals with different episodes consisting of several symptoms that last for at least 2 weeks.
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Science Daily: Pharmacology News
FEBRUARY 15, 2024
Our brains are 'programmed' to learn more from people we like -- and less from those we dislike. This has been shown by researchers in cognitive neuroscience in a series of experiments.
Broad Institute
FEBRUARY 16, 2024
Study finds youth-onset diabetes is a genetically distinct form of the disorder By Claire Hendershot February 16, 2024 Breadcrumb Home Study finds youth-onset diabetes is a genetically distinct form of the disorder Researchers suggest diabetes exists in multiple forms on a spectrum of varying genetic factors and symptoms. By Claire Hendershot February 16, 2024 Image by Ricardo Job-Reese, Broad Communications.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
BioPharma Drive: Drug Pricing
FEBRUARY 15, 2024
Analysts pressed Alnylam executives on the reasons for the changes to HELIOS-B, a Phase 3 study in ATTR amyloidosis with cardiomyopathy that is important to the company’s future.
Nvidia Developer: Drug Discovery
FEBRUARY 14, 2024
The quest for new, effective treatments for diseases that remain stubbornly resistant to current therapies is at the heart of drug discovery. This traditionally. The quest for new, effective treatments for diseases that remain stubbornly resistant to current therapies is at the heart of drug discovery. This traditionally long and expensive process has been radically improved by AI techniques like deep learning, empowered by the rise of accelerated computing.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Codon
FEBRUARY 13, 2024
Tom Ireland writes about the companies and technologies that are reimagining phage therapy. Read it on our website here. Illustration by David S. Goodsell, RCSB Protein Data Bank and Scripps Research. doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of u
BioPharma Drive: Drug Pricing
FEBRUARY 14, 2024
Latigo Biotherapeutics has raised $135 million to develop drugs that block NaV1.8, a target shared by a Vertex therapy that just succeeded in Phase 3 testing.
Science Daily: Pharmacology News
FEBRUARY 12, 2024
You can mend a broken heart this valentine s day now that researchers invented a new hydrogel that can be used to heal damaged heart tissue and improve cancer treatments.
Drugs.com
FEBRUARY 13, 2024
TUESDAY, Feb. 13, 2024 -- Mammograms are a lifesaving misery for middle-aged women, but a new tool could make getting a breast cancer screening as easy as spitting.Literally.A new hand-held biosensor can detect breast cancer biomarkers from a tiny.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Perficient: Drug Development
FEBRUARY 14, 2024
Revolutionizing B2C Commerce: The Impact of Generative AI In the dynamic landscape of commerce and consumer-driven markets, Business-to-Consumer (B2C) organizations are increasingly turning to generative AI to revolutionize their operations and enhance customer experiences. Generative AI, a subset of artificial intelligence, empowers these organizations to create content, personalize interactions, and optimize various aspects of their business processes.
BioPharma Drive: Drug Pricing
FEBRUARY 14, 2024
The company and partner Biogen say signs from payers and doctors suggest the launch of Zurzuvae, the first oral therapy for PPD, is off to a good start.
Science Daily: Pharmacology News
FEBRUARY 12, 2024
Growing cartilage tissue in the lab could help patiens with injuries, but it is very hard to make the tissue grow in exactly the right shape. A new approach could solve this problem: Tiny spherical containers are created with a high-resolution 3D printer. These containers are then filled with cells and assembled into the desired shape. The cells from different containers connect, the container itself is degradable and eventually disappears.
NIOSH Science Blog: Drugs
FEBRUARY 14, 2024
Finding the right fit is one of the most important parts of a relationship. You don’t just grab any old fish from the sea that swims by and hope for the best. First, it’s necessary to test the waters and ensure you’re simpatico before settling on a partner. It’s Valentine’s Day, and yes, this advice could apply to your romantic life, but we also love to use today to show our love of respirators and we love to play matchmaker on your behalf as well.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
FEBRUARY 16, 2024
FRIDAY, Feb. 16, 2024 (HealthDay news) -- A drug first developed to treat cocaine addiction might also help slow the spread of advanced colon cancer, a new study suggests.The drug vanoxerine appears to suppress cancer stem cell activity by.
Drug Target Review
FEBRUARY 12, 2024
Denise, could you share some insights into your journey at Onyx Scientific, highlighting key milestones and challenges you’ve faced during your nearly 25 years with the company? At the turn of the millennium in early 2000, I was approached by the founders of Onyx Scientific to join the company as their Business Development Manager. I considered this to be an exciting opportunity and became part of the original team that established the company.
KIF1A
FEBRUARY 10, 2024
#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research Unraveling the genetic landscape of undiagnosed cerebellar ataxia in Brazilian patients In this week’s article, researchers in Brazil performed genetic sequencing on 87 patients with cerebe
National Drug & Alcohol Research Centre Blog
FEBRUARY 12, 2024
Who’s most likely to die from alcohol poisoning, and what do they drink? A new study led by researchers at the National Drug and Alcohol Research Centre (NDARC), UNSW Sydney, has explored the circumstances of death and characteristics of fatal alcohol poisoning cases. The study, published in Drug and Alcohol Review, examined deaths from acute alcohol poisoning in Australia, 2011–2022.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
FEBRUARY 16, 2024
FRIDAY, Feb. 16, 2024 -- The U.S. Centers for Disease Control and Prevention is weighing whether to recommend another COVID booster shot this spring, most likely for those who are vulnerable to severe illness.An advisory panel to the CDC is.
Science Daily: Pharmacology News
FEBRUARY 15, 2024
New research reveals the scale of inappropriate reforestation projects across Africa. A new study reveals that an area the size of France is threatened by forest restoration initiatives, such as the AFR100 initiative (African Forest Landscape Restoration Initiative), due to inappropriate restoration in the form of tree-planting.
Drug Target Review
FEBRUARY 16, 2024
Scientists at the University of Pittsburgh have discovered that tumours with a greater intragenic rearrangement (IGR) burden may respond better to immune checkpoint blockades (ICB). This could lead to more precise treatment for patients with cancers like oesophageal, breast, ovarian and endometrial, which solves an unmet need to discover genetic abnormalities that predict ICB responses in these tumour types.
Perficient: Drug Development
FEBRUARY 13, 2024
What is Microservices Architecture? Microservices Architecture Software development follows an architectural and organizational approach where small independent services communicate with each other through well-defined APIs. Overview of Microservices Architecture Microservices architecture provides a set of rules and guidelines to develop a project as a set of loosely coupled/de-coupled services, and this can be implemented using Spring Boot + Spring Cloud + Netflix and many other tools.
Drugs.com
FEBRUARY 14, 2024
WEDNESDAY, Feb. 14, 2024 -- Acupuncture may protect people with rheumatoid arthritis (RA) from stroke, new research suggests.The study indicates that a course of acupuncture treatment may lower blood levels of inflammatory proteins called.
Science Daily: Pharmacology News
FEBRUARY 13, 2024
Babies playfully tease others as young as eight months of age. Since language is not required for this behavior, similar kinds of playful teasing might be present in non-human animals. Now cognitive biologists and primatologists have documented playful teasing in four species of great apes. Like joking behavior in humans, ape teasing is provocative, persistent, and includes elements of surprise and play.
BioPharma Drive: Drug Pricing
FEBRUARY 16, 2024
The disclosure the experimental therapy missed its trial goal comes after Sanofi had earmarked the drug for advancement into Phase 3.
PLOS: DNA Science
FEBRUARY 15, 2024
I love the spectacular symbiosis of my vegetable garden as harvest time approaches. Beanstalks spiral up cornstalks, their tendrils teasing nearby tomato stems. Below, broad leaves protect ballooning squashes from the slugs that appear, seemingly from nowhere, after a rain, while providing water for passing furry creatures. The synergism of a garden is an ancient and somewhat obvious idea.
Drugs.com
FEBRUARY 16, 2024
FRIDAY, Feb. 16, 2024 -- People threatened by accidental exposure to foods they're allergic to may have a new weapon of defense: On Friday, the U.S. Food and Drug Administration expanded the use of the asthma drug Xolair to help prevent.
Science Daily: Pharmacology News
FEBRUARY 15, 2024
A team found evidence for hydrothermal or metamorphic activity within the icy dwarf planets Eris and Makemake, located in the Kuiper Belt. Methane detected on their surfaces has the tell-tale signs of warm or even hot geochemistry in their rocky cores, which is markedly different than the signature of methane from a comet.
BioPharma Drive: Drug Pricing
FEBRUARY 16, 2024
Kelonia will receive $40 million upfront through a partnership to develop “off-the-shelf” cell therapies for cancer.
NIOSH Science Blog: Drugs
FEBRUARY 15, 2024
The American Journal of Public Health recently published a special supplement with 15 articles focusing on health worker mental health. This special issue of the journal was sponsored and edited by the National Institute for Occupational Safety and Health (NIOSH) and stems from the health worker mental health initiative from the Centers for Disease Control and Prevention and NIOSH.
Drugs.com
FEBRUARY 12, 2024
MONDAY, Feb. 12, 2024 -- Weight loss drugs like Ozempic and Zepbound can lead to better heart health for people struggling with excess weight or diabetes, a University of Michigan cardiologist says. However, these medications help the heart best.
Science Daily: Pharmacology News
FEBRUARY 16, 2024
A research team that had previously succeeded in synthesizing fumaric acid using bicarbonate and pyruvic acid, and carbon dioxide collected directly from the gas phase as one of the raw materials, has now created a new photosensitizer and developed a new artificial photosynthesis technology, effectively doubling the yield of fumaric acid production compared to the previous method.
SCIENMAG: Medicine & Health
FEBRUARY 16, 2024
A female White-eared opossum (Didelphis albiventris) found dead in 2021 in Bosque dos Jequitibás Park in the center of Campinas, one of the largest cities in São Paulo state, Brazil, died from rabies meningoencephalitis, according to a group of researchers at the University of São Paulo (USP) and Adolfo Lutz Institute (IAL), the regional reference […]
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