Companies Seek To Increase Life Span By A Decade Or More
Forbes: Drug Truths
OCTOBER 17, 2023
But keep in mind that it’s going to be a long while before such drugs are actually available.
Sat.Oct 14, 2023 - Fri.Oct 20, 2023
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CVS Pulling Popular Cold Meds From Shelves After Report Deems Them to Be Useless
Drugs.com
OCTOBER 20, 2023
FRIDAY, Oct. 20, 2023 -- CVS Health plans to pull cold medications that contain phenylephrine from its store shelves after federal regulators determined recently that the decongestant doesn’t work. Oral phenylephrine is an active ingredient.
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With $56M, a Mayo Clinic-backed startup takes aim at radiopharmaceutical roadblocks
BioPharma Drive: Drug Pricing
OCTOBER 17, 2023
Nucleus RadioPharma, a contract developer and manufacturer, is expanding at a time when investment is pouring into the radiopharmaceutical drug field.
CDD Vault Update (October 2023)
Collaborative Drug
OCTOBER 16, 2023
Keyword Searching When using the Keywords search feature in the main Explore Data > Search tab, there is a new “exact” search option available when you select a specific, non-numeric Molecule or Batch field.
Bridging Innovation & Patient Care: The Growing Role of AI
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Red meat consumption associated with increased type 2 diabetes risk
Science Daily: Pharmacology News
OCTOBER 19, 2023
People who eat just two servings of red meat per week may have an increased risk of developing type 2 diabetes compared to people who eat fewer servings, and the risk increases with greater consumption, according to a new study. Researchers also found that replacing red meat with healthy plant-based protein sources, such as nuts and legumes, or modest amounts of dairy foods, was associated with reduced risk of type 2 diabetes.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
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Beam to lay off 100 employees, seek partners in research restructuring
BioPharma Drive: Drug Pricing
OCTOBER 19, 2023
The base editing specialist will prioritize medicines for sickle cell and alpha-1 antitrypsin deficiency, while trimming its plans for other programs in cancer and hepatitis B.
Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2
Covalent Modifiers
OCTOBER 19, 2023
Ramachandran, S., Makukhin, N., Haubrich, K. et al. Nat Commun 14, 6345 ( 2023 ). [link] The Src homology 2 (SH2) domain recognizes phosphotyrosine (pY) post translational modifications in partner proteins to trigger downstream signaling. Drug discovery efforts targeting the SH2 domains have long been stymied by the poor drug-like properties of phosphate and its mimetics.
Ketamine's effect on depression may hinge on hope
Science Daily: Pharmacology News
OCTOBER 19, 2023
In an unusual trial, researchers found that a patient's belief that they had received ketamine, even if they didn't, could improve their depression.
Put These Foods on Your Grocery List for Better Vision
Drugs.com
OCTOBER 20, 2023
FRIDAY, Oct. 20, 2023 -- Nutrition is important for your whole body, including those two small organs through which you look at the world. The same diet that’s good for your heart and the rest of your body will also help your eyes, according.
From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
BrainStorm, after setbacks, withdraws approval application for ALS drug
BioPharma Drive: Drug Pricing
OCTOBER 18, 2023
A panel of FDA advisers last month found BrainStorm’s data unconvincing. The company now says a Phase 3b study will be needed for its NurOwn cell therapy to have a shot at an approval.
Defining the Cell Surface Cysteinome using Two-step Enrichment Proteomics
Covalent Modifiers
OCTOBER 20, 2023
Tianyang Yan , Lisa Boatner , Liujuan Cui , Peter Tontonoz , Keriann Backus bioRxiv 2023.10.17.562832; doi: [link] The plasma membrane proteome is a rich resource of functional and therapeutically relevant protein targets. Distinguished by high hydrophobicity, heavy glycosylation, disulfide-rich sequences, and low overall abundance, the cell surface proteome remains undersampled in established proteomic pipelines, including our own cysteine chemoproteomics platforms.
Generating clean electricity with chicken feathers
Science Daily: Pharmacology News
OCTOBER 20, 2023
Turning unused waste from food production into clean energy: Researchers are using chicken feathers to make fuel cells more cost-effective and sustainable.
In Study, Diabetes Drug Mounjaro Helped Dieters Shed an Average of 60 Pounds
Drugs.com
OCTOBER 17, 2023
MONDAY, Oct. 16, 2023 -- A new trial demonstrates the power of the diabetes drug Mounjaro in fighting obesity, helping folks who used the medication lose about 60 pounds. "In this study, people who added tirzepatide [Mounjaro] to diet and exercise.
How Machine Learning Drives Clinical Trial Efficiency
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Merck cancer drug deal caps pharma investment influx into ‘ADC’ field
BioPharma Drive: Drug Pricing
OCTOBER 20, 2023
With the alliance, Merck joins Pfizer, AstraZeneca and Gilead in staking major bets on the potential for antibody-drug conjugates to reshape cancer treatment.
Ultra-rapid Electrophilic Cysteine Arylation [@WangGroupURICHM]
Covalent Modifiers
OCTOBER 19, 2023
Bradley M. Lipka, Daniel S. Honeycutt, Gregory M. Bassett, Taylor N. Kowal, Max Adamczyk, Zachary C. Cartnick, Vincent M. Betti, Jacob M. Goldberg, and Fang Wang Journal of the American Chemical Society 2023 DOI: 10.1021/jacs.3c10334 Rapid bond-forming reactions are crucial for efficient bioconjugation. We describe a simple and practical strategy for facilitating ultra-rapid electrophilic cysteine arylation.
Molecular age of the eye determined
Science Daily: Pharmacology News
OCTOBER 19, 2023
A team of researchers have mapped almost 6,000 proteins from different cell types within the eye by analyzing tiny drops of eye fluid that are routinely removed during surgery. The researchers used an AI model to create a 'proteomic clock' from this data that can predict a healthy person's age based on their protein profile. The clock revealed that diseases such as diabetic retinopathy and uveitis cause accelerated aging within specific cell types.
Amazon to Test Drones to Deliver Prescriptions to Your Door
Drugs.com
OCTOBER 20, 2023
THURSDAY, Oct. 19, 2023 -- Soon, you may be able to step out on your front porch and wait for your prescription medication to drop from the sky. On Wednesday, Amazon Pharmacy announced that it is starting to test speedy prescription drug delivery.
Deliver Fast, Flexible Clinical Trial Insights with Spotfire
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Ultragenyx to spin out new company around Alzheimer’s gene therapy
BioPharma Drive: Drug Pricing
OCTOBER 18, 2023
CEO Emil Kakkis says the company's findings are too exciting to ignore, but the “high-risk, high-return” venture needs to be pursued outside the organization.
Drug Discovery Industry Roundup with Barry Bunin — October 17, 2023
Collaborative Drug
OCTOBER 17, 2023
Drug Discovery Industry Roundup with Barry Bunin — October 17, 2023
Wearable device makes memories and powers up with the flex of a finger
Science Daily: Pharmacology News
OCTOBER 18, 2023
Researchers have invented an experimental wearable device that generates power from a user's bending finger and can create and store memories, in a promising step towards health monitoring and other technologies.
Living Alone Raises Americans' Cancer Risk by Nearly a Third
Drugs.com
OCTOBER 20, 2023
THURSDAY, Oct. 19, 2023 -- People who live alone have a greater risk of dying from cancer, a new study warns. Researchers from the American Cancer Society showed that U.S. adults who live alone had a 32% higher risk of cancer death than those who.
Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
The top biopharma conferences in 2024
BioPharma Drive: Drug Pricing
OCTOBER 16, 2023
A few key meetings remain this year, like ESMO and ASH, while next year’s events are already being planned. Here’s a list of conferences to keep in mind.
Health Literacy Month: How industry communication can impact patient health literacy
Antidote
OCTOBER 20, 2023
Since 1999, October has been designated as Health Literacy Month , a month dedicated to promoting patient-centricity in healthcare communications across the industry. Health literacy refers to a person’s ability to find, understand, and use health-related services and make informed decisions for themselves and others.
Black holes could come in 'perfect pairs' in an ever expanding Universe
Science Daily: Pharmacology News
OCTOBER 19, 2023
Researchers have shown it's theoretically possible for black holes to exist in perfectly balanced pairs -- held in equilibrium by a cosmological force -- mimicking a single black hole.
Olympian Mary Lou Retton Suffers Setback in Battle With Rare Form of Pneumonia
Drugs.com
OCTOBER 20, 2023
THURSDAY, Oct. 19, 2023 -- Former Olympic gymnast Mary Lou Retton has suffered a "scary setback" as she fights a rare type of pneumonia while in the intensive care unit of a hospital, her family said Wednesday. The 55-year-old, who lives in the.
Novo’s Uli Stilz on biotech innovation and the future of diabetes drugs
BioPharma Drive: Drug Pricing
OCTOBER 17, 2023
The Danish drugmaker's innovation hub in Boston has teamed up with the Broad Institute, Mass General Brigham, Harvard and Yale, expanding its research into cardiometabolic diseases.
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