Sat.Nov 12, 2022 - Fri.Nov 18, 2022

article thumbnail

Lab Innovations celebrates its ten year anniversary in style

Drug Discovery Today

98 per cent of exhibitors sign up for Lab Innovations 2023 after a record breaking event this year

113
113
article thumbnail

Sinomenine attenuates lipopolysaccharide?induced inflammation and apoptosis of WI?38 cells by reducing glutathione S?transferase M1 expression

Chemical Biology and Drug Design

Sinomenine protected WI-38 cells against lipopolysaccharide-caused viability reduction, inflammation and apoptosis via downregulating glutathione S-transferase M1 expression. Abstract Pediatric pneumonia is an infectious lung disease with high morbidity and mortality. Sinomenine, an alkaloid extracted from Caulis Sinomenii , exerts anti-inflammatory and anti-apoptotic activities.

Treatment 100
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Lung Cancer Awareness Month: Helping patients through research

Antidote

Lung Cancer Awareness Month occurs every November with the purpose of increasing general knowledge of lung cancer and the treatment options available to patients who have been diagnosed. While lung cancer is still a prevalent disease, there have been many advancements in the lung cancer treatment space over the years, and medical research studies are consistently underway to find better solutions for patients.

article thumbnail

Which pharmaceutical companies have the most suppository dosed drugs?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most suppository dosed drugs. For a different perspective, see the most popular dosage types. The companies with the most suppository dosed drugs…. The post Which pharmaceutical companies have the most suppository dosed drugs? appeared first on DrugPatentWatch - Make Better Decisions.

article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

IBM and Algorithmiq join forces to pave the way toward useful quantum advantage for quantum chemistry

Drug Discovery Today

Collaboration with innovative Finnish software company to explore how to reduce the time and cost of drug discovery and development using quantum computers

Drugs 113
article thumbnail

Behind the GoodRx-Express Scripts Partnership: How PBMs Profit from Discount Cards in Pharmacy Benefits

Drug Channels

Last week, GoodRx announced that it would become the exclusive prescription discount card provider for the commercial beneficiaries of Cigna’s Express Scripts. Links below. The rise of discount card pricing within pharmacy benefit plans is a positive development. Patients get access to market prices that can be lower than their PBM’s contracted rate.

More Trending

article thumbnail

Which pharmaceutical companies have the most drug patents in Cyprus?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Cyprus. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is…. The post Which pharmaceutical companies have the most drug patents in Cyprus? appeared first on DrugPatentWatch - Make Better Decisions.

article thumbnail

Discovery Park celebrates 10 years and plans to double jobs over the next decade

Drug Discovery Today

The team behind the success of one the country’s largest science and innovation park has announced its plans to grow and double the number of people employed on site as it celebrates a decade of delivering jobs and investment in the South East.

Science 113
article thumbnail

Raters & Therapists: Protecting the validity of your study’s data in a psychedelic trial

Conversations in Drug Development Trends

Psychiatry has long embraced treatment options other than pharmaceuticals. So, it should come as no surprise that as the field explores the use of psychedelics as treatment options for mental illnesses, they are studying the use of psychological therapy alongside them. This is called “psychedelic-assisted psychotherapy” (PAP). But in a clinical trial setting, what role does a therapist play and how do they affect the clinical trial data?

Trials 59
article thumbnail

Engage Specialists in Their Workflow With GoodRx Provider Mode

Drug Channels

Today’s guest post comes from Bansi Nagji, President of Healthcare at GoodRx. Bansi explains how GoodRx Provider Mode delivers a prescription savings flow that offers health care professionals (HCPs) efficient access to the information they need at critical moments of care. Click here to learn how GoodRx Provider Mode can help manufacturers reach and engage HCPs.

Drugs 52
article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Which pharmaceutical companies have the most drug patents in Serbia?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Serbia. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is…. The post Which pharmaceutical companies have the most drug patents in Serbia? appeared first on DrugPatentWatch - Make Better Decisions.

article thumbnail

Nerve cell discovery may lead to better treatment for diseases of the nervous system

Drug Discovery Today

A discovery that may improve treatment options for patients with neurodegenerative diseases has been made by scientists at King’s College London and the University of Bath.

Treatment 113
article thumbnail

AhR activators – friend or foe?

Metabolite Tales Blog

AhR activators – friend or foe? A very usual metabolite, a very unusual pharmacological target, and an unexpected serious adverse effect that combined to halt the development of laquinimod and roquinimex By Andrew Parkinson, XPD Consulting Laquinimod (Nervantra), a drug previously under development by Teva Pharmaceuticals for the treatment of multiple sclerosis, is converted by CYP-dependent N -de-ethylation to N- desethyl-laquinimod (DELAQ).

article thumbnail

Understanding FDA’s Draft Guidance on Ethical Considerations for Involving Children in Clinical Trials

Advarra

In 2016, the Food and Drug Administration (FDA) approved Spinraza (nusinersen). It was the first drug to treat children with spinal muscular atrophy (SMA), a disease affecting children’s muscular strength and movement. While the FDA’s approval of nusinersen may not seem extraordinary, it was. Nusinersen’s approval marked the first time nonclinical data supported conducting initial clinical trials involving children.

article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

Which pharmaceutical companies have the most drug patents in Japan?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Japan. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is…. The post Which pharmaceutical companies have the most drug patents in Japan? appeared first on DrugPatentWatch - Make Better Decisions.

article thumbnail

A Roadmap for Introducing Novel Excipients: How to Approach Excipient Qualification with the FDA

The Premier Consulting Blog

One of the most common formulation issues that sponsors of new drug or biologic products face is the qualification of novel excipients. Although novel excipients can be a part of any new drug application (NDA) or biologics license application (BLA) development program, they seem to be more common with the 505(b)(2) pathway, since many companies use cutting-edge delivery technologies to solve issues associated with previously approved drugs.

FDA 52
article thumbnail

Latest news on drug repurposing in oncology #18

The Anticancer Fund

17 November 2022 Language EN Drug repurposing is a strategy for identifying new uses for approved drugs, outside the scope of the original indication. It is one of the focus areas of the Anticancer Fund. Below, we have listed recent findings about the repurposing of generic drugs in oncology. Our intention is to help bring these findings to the attention of the broader cancer research community.

Drugs 52
article thumbnail

What is Hidradenitis Suppurativa: Signs, Causes and Treatments

Olympian Clinical Research

Hidradenitis suppurativa (HS) is a chronic, inflammatory skin condition that is not well-known. In fact, patients with HS often complain of pimples, sores or lumps on their armpits or groin area, having no idea these are actually symptoms of a more serious condition. Though it’s not well known, HS is more common than you might think, and awareness and education can help people with HS get the diagnosis and help they need.

article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

New patent for Bioxcel drug IGALMI

Drug Patent Watch

Annual Drug Patent Expirations for IGALMI Igalmi is a drug marketed by Bioxcel and is included in one NDA. There is one patent protecting this drug. This drug has twenty…. The post New patent for Bioxcel drug IGALMI appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
article thumbnail

Optimizing the Market Value of an Asset with Multiple Potential Indications

The Premier Consulting Blog

Research and development (R&D) investment decisions may be the largest risk taken by drug developers. When a single asset has broad applicability, sponsors must perform a thorough evaluation of its scientific, regulatory, clinical, patient, and commercial elements to determine the best path forward, especially if they are positioning themselves for raising capital.

article thumbnail

How healthtech companies can drive app downloads

Antidote

Increasing app downloads can feel like an uphill battle for companies in the competitive healthtech space. Because this is a crowded industry, user acquisition can be a considerable challenge — but Antidote is well-positioned to assist.

52
article thumbnail

Travel scholarship recipients share highlights from their week at NDARC

National Drug & Alcohol Research Centre Blog

In September this year, NDARC awarded travel scholarships to early career researchers (ECRs) and higher degree research students (HDRs) in the alcohol and other drugs (AOD) sector. The scholarship recipients attended key events including the ASCEND Symposium, the 2022 NDARC Annual Research Symposium and the NDARC Early Career Networking Event. Gabrielle Caluzzi, a postdoctoral researcher at the Centre for Alcohol Policy Research, La Trobe University, and Carmen Lim, a PhD candidate at The Nation

article thumbnail

New patent expiration for Ani Pharms drug VEREGEN

Drug Patent Watch

Annual Drug Patent Expirations for VEREGEN Veregen is a drug marketed by Ani Pharms and is included in one NDA. It is available from two suppliers. There are three patents…. The post New patent expiration for Ani Pharms drug VEREGEN appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
article thumbnail

An 18 Month Journey From Inception To IPO

LifeSciVC

By Ivana Magovčević-Liebisch PhD, JD, CEO of VIGIL NEUROSCIENCE, as part of the From The Trenches feature of LifeSciVC Compared to most industries, biotech life cycles are lengthy. From R&D and clinical development to regulatory approval, it takes an average of 12 to 14 years for an idea to become a reality. Fueling the development of a novel therapeutic often requires multiple rounds of financing, and the time between rounds as well as the time from founding to initial public offering (IPO)

article thumbnail

Five Strikes Needed To Dismiss A Questionable Case

Drug & Device Law

Drug manufacturers are not insurers against injury from or while taking medications. Neither are distributors or pharmacies. Just because a patient experiences a complication while taking a medication, including the very condition the medication is supposed to help prevent, does not mean that some person or entity should be liable to the patient for her injuries.

article thumbnail

Travel scholarship recipients share highlights from their week at NDARC

National Drug & Alcohol Research Centre Blog

In September this year, NDARC awarded travel scholarships to early career researchers (ECRs) and higher degree research students (HDRs) in the alcohol and other drugs (AOD) sector. The scholarship recipients attended key events including the ASCEND Symposium, the 2022 NDARC Annual Research Symposium and the NDARC Early Career Networking Event. Gabrielle Caluzzi, a postdoctoral researcher at the Centre for Alcohol Policy Research, La Trobe University, and Carmen Lim, a PhD candidate at The Nation

article thumbnail

New patent expiration for Bayer Hlthcare drug XOFIGO

Drug Patent Watch

Annual Drug Patent Expirations for XOFIGO Xofigo is a drug marketed by Bayer Hlthcare and is included in one NDA. It is available from one supplier. There is one patent…. The post New patent expiration for Bayer Hlthcare drug XOFIGO appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
article thumbnail

New patent for NOVO drug OZEMPIC

Drug Patent Watch

Annual Drug Patent Expirations for OZEMPIC Ozempic is a drug marketed by Novo and is included in one NDA. It is available from two suppliers. There are twenty-five patents protecting…. The post New patent for NOVO drug OZEMPIC appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
article thumbnail

Which pharmaceutical companies have the most drug patents in Austria?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Austria. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is…. The post Which pharmaceutical companies have the most drug patents in Austria? appeared first on DrugPatentWatch - Make Better Decisions.

article thumbnail

New patent expiration for Intercept Pharms drug OCALIVA

Drug Patent Watch

Annual Drug Patent Expirations for OCALIVA Ocaliva is a drug marketed by Intercept Pharms Inc and is included in one NDA. It is available from one supplier. There are ten…. The post New patent expiration for Intercept Pharms drug OCALIVA appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
article thumbnail

New patent for Daiichi Sankyo drug TURALIO

Drug Patent Watch

Annual Drug Patent Expirations for TURALIO Turalio is a drug marketed by Daiichi Sankyo Inc and is included in one NDA. It is available from one supplier. There are twelve…. The post New patent for Daiichi Sankyo drug TURALIO appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
article thumbnail

New patent for Mitsubishi Tanabe drug RADICAVA ORS

Drug Patent Watch

Annual Drug Patent Expirations for RADICAVA+ORS Radicava Ors is a drug marketed by Mitsubishi Tanabe and is included in one NDA. It is available from one supplier. There are two…. The post New patent for Mitsubishi Tanabe drug RADICAVA ORS appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52
article thumbnail

New tentative approval for Teva Pharms drug eltrombopag

Drug Patent Watch

[![eltrombopag structure]([link] Eltrombopag is the generic ingredient in two branded drugs marketed by Novartis and is included in two NDAs. There are eight patents protecting this compound. There are four…. The post New tentative approval for Teva Pharms drug eltrombopag appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 52