Sat.Jul 13, 2024 - Fri.Jul 19, 2024

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Ant insights lead to robot navigation breakthrough

Science Daily: Pharmacology News

Have you ever wondered how insects are able to go so far beyond their home and still find their way? The answer to this question is not only relevant to biology but also to making the AI for tiny, autonomous robots. Drone-researchers felt inspired by biological findings on how ants visually recognize their environment and combine it with counting their steps in order to get safely back home.

Research 142
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Where's the Synthetic Blood?

Codon

Dr. Keith Neeves gives a history of blood transfusions and explains why it will be difficult to scale up the creation of synthetic blood for Issue 03 of Asimov Press. We are mostly blood. Of the 36 trillion cells in the human body, 32 trillion are blood cells. These blood cells synchronize the delivery of oxygen to every tissue in your body, fight pathogens, and heal wounds.

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Artiva prices $167M IPO, riding optimism for autoimmune cell therapy

BioPharma Drive: Drug Pricing

The offering comes days after the publication of a paper showing what analysts said was early proof that “off-the-shelf” cell therapies can treat inflammatory diseases.

Therapies 127
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InMed’s INM-901 Demonstrates Potential as a Multi-factorial Approach to Treating Alzheimer’s Disease

Fierce BioTech

InMed’s INM-901 Demonstrates Potential as a Multi-factorial Approach to Treating Alzheimer’s Disease jpiatt Fri, 07/19/2024 - 09:56

Disease 124
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Evidence for butchery of giant armadillo-like mammals in Argentina 21,000 years ago

Science Daily: Pharmacology News

Cut marks on fossils could be evidence of humans exploiting large mammals in Argentina more than 20,000 years ago, according to a new study.

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German Patient is 7th Person Probably Cured of HIV

Drugs.com

FRIDAY, July 19, 2024 -- A German man has become the seventh person to apparently be cured of HIV, researchers report.The 60-year-old man, referred to as the “next Berlin Patient,” was treated with a stem cell transplant in October 2015 for acute my.

Research 116

More Trending

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An immune factor in the brain plays critical roles in neuron function and aging

Broad Institute

An immune factor in the brain plays critical roles in neuron function and aging By Tom Ulrich July 19, 2024 Breadcrumb Home An immune factor in the brain plays critical roles in neuron function and aging Study highlights unexpected interactions between innate immune system and neurons, raises questions about additional roles for immune system in the brain with aging.

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Good timing: Study unravels how our brains track time

Science Daily: Pharmacology News

Ever hear the old adage that time flies when you're having fun? A new study suggests that there's a lot of truth to the trope.

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Studies Support Use of Daily Antibiotic to Prevent STDs in High-Risk Groups

Drugs.com

FRIDAY, July 19, 2024 -- It's long been known that popping the antibiotic doxycycline within 72 hours of a risky sexual encounter can greatly reduce a person's risk for a sexually transmitted infection (STI). In fact, the U.S. Centers for Disease.

Disease 116
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Obesity pill from Roche shows promising weight loss in small study

BioPharma Drive: Drug Pricing

Treatment led to "clinically meaningful" weight loss over four weeks, but longer studies will be needed to compare it to Wegovy and Zepbound.

Treatment 117
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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What is the medical definition of obesity?

Antidote

Obesity, a condition that impacts 2 out of 5 adults in the United States , has become a significant health concern, both due to the impacts it has on individuals with the condition and the effect it can have on the overall medical system. It is estimated that obesity is responsible for nearly $1.73 billion in excess treatment costs annually, compounded by the fact that individuals with obesity are far more likely to have other conditions such as hypertension, diabetes, and osteoarthritis.

Treatment 111
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Scientists develop new artificial intelligence method to create material 'fingerprints'

Science Daily: Pharmacology News

Researchers have developed a new technique that pairs artificial intelligence and X-ray science.

Science 132
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New MS Drug Kesimpta May Help Keep Symptoms at Bay

Drugs.com

THURSDAY, July 18, 2024 -- A new monoclonal antibody treatment called Kesimpta (ofatumumab) appears to improve on an older drug in pushing multiple sclerosis (MS) into remission, a new trial shows.Funded by Kesimpta's maker, Novartis, the trial.

Drugs 116
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In strengthening Spravato sales, a positive sign for psychedelic drugs

BioPharma Drive: Drug Pricing

Jefferies analyst Andrew Tsai views growing sales for J&J’s depression treatment as evidence that psychedelics like it can be commercially viable.

Treatment 110
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Jessie Rees Foundation and The Foundation for Excellence Both Receive $5,000 Perficient Global Grant

Perficient: Drug Development

Perficient’s Giving Employee Resource Group (ERG) recently introduced the Perficient Gives Global Grants Program , which gives colleagues the opportunity to nominate charitable organizations from around the world to receive a $5,000 donation from Perficient. After carefully evaluating each nomination, Perficient’s Giving ERG leadership team selected the first five organizations to receive a donation.

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New geological datings place the first European hominids in the south of the Iberian Peninsula 1.3 million years ago

Science Daily: Pharmacology News

One of the most important controversies about human evolution and expansion is when and by what route the first hominids arrived in Europe from the African continent. Now, geological dating techniques at the Orce sites (Baza basin, Granada, Spain) place the human remains found in this area as the oldest in Europe, at approximately 1.3 million years old.

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Fall of Roe v. Wade Has Made Access to Ob/Gyns Tougher in Many States: Report

Drugs.com

THURSDAY, July 18, 2024 -- Ever since the Supreme Court overturned Roe v. Wade in June 2022, even more women have struggled to find reproductive care, a new report warns.Issued Thursday by the Commonwealth Fund, the report shows that women living.

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Sionna revives AbbVie’s cystic fibrosis drugs, eyeing a shot at Vertex

BioPharma Drive: Drug Pricing

The well-funded startup says drugs AbbVie abandoned last year could form a combination regimen with “superior efficacy” to Vertex’s market-leading medicines.

Drugs 109
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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At Long Last, FDA Unveils Plan for Rare Disease Innovation Hub

FDA Law Blog: Drug Discovery

By Sarah Wicks & James E. Valentine & Frank J. Sasinowski — On July 17, 2024, FDA announced the establishment of a Rare Disease Innovation Hub (the “Hub”) to enhance and improve outcomes for patients with rare diseases and conditions by focusing on rare disease drug and biological product development across the Agency’s Center for Drug Evaluation and Research (“CDER”) and Center for Biologics Evaluation and Research (“CBER”).

FDA 105
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Waste Styrofoam can now be converted into polymers for electronics

Science Daily: Pharmacology News

A new study describes a chemical reaction that can convert Styrofoam into a high-value conducting polymer known as PEDOT:PSS. Researchers also noted that the upgraded plastic waste can be successfully incorporated into functional electronic devices, including silicon-based hybrid solar cells and organic electrochemical transistors.

Research 130
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Science Reveals 'Magic Mushroom' Chemical's Mind-Altering Effects

Drugs.com

THURSDAY, July 18, 2024 -- “Magic” mushrooms achieve their psychedelic effects by temporarily scrambling a brain network involved in introspective thinking like daydreaming and remembering, a new study reports.Brain scans of people who took psi.

Science 115
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Navigating Patent Opposition in Drug Patenting: A Comprehensive Guide

Drug Patent Watch

Introduction Patent oppositions are a crucial tool in the pharmaceutical industry, allowing civil society to challenge the validity of patents […] Source

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Nanoemulsion based lipid nanoparticles for effective demethylcantharidin delivery to cure liver cancer

Chemical Biology and Drug Design

Demethylcantharidin (DEM) is a widely used antitumor drug; however, its poor tumor targeting and serious organotoxicity limit its application. The aim of this study was to develop a new drug delivery system for efficient delivery of DEM. DEM, demethylcalcin; DNLNs, nanoemulsion based lipid nanoparticles containing demethylcantharidin; EPR, enhanced permeability and retention; PEG-400, polyethylene glycol 400.

Drugs 100
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Psilocybin generates psychedelic experience by disrupting brain network

Science Daily: Pharmacology News

Researchers report that psilocybin, the active ingredient in magic mushrooms, destabilizes a critical network of brain areas involved in introspective thinking. The findings provide a neurobiological explanation for the drug's mind-bending effects.

Research 129
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Irregular Sleep Could Raise Your Odds for Diabetes

Drugs.com

WEDNESDAY, July 17, 2024 (HeathDay News) -- Sleeping long hours one night but only a few hours the next can be unhealthy, with a new study finding "irregular" sleep patterns could be a risk factor for type 2 diabetes.The results "underscore the.

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Winning Drug Patent Disputes: Proven Strategies for Pharmaceutical Companies

Drug Patent Watch

The High Stakes of Pharmaceutical Patent Litigation In the fiercely competitive pharmaceutical industry, patent disputes can make or break a […] Source

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Interrogating a Compound Library in Search of an Inhibitor for TREM-like Transcript-1 to Fibrinogen Binding [Cardiovascular]

ASPET

Cardiovascular disease (CVD) remains one of leading causes of death worldwide. Aberrant platelet function mediate fibrin(ogen) rich thrombi that lead to occlusive thrombi associated with mortality. The receptor, TREM-like transcript-1 (TLT-1), stored in the platelet a-granules and released upon platelet activation, binds fibrinogen and von Willebrand factor.

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Widespread practice among athletes harms both performance and health

Science Daily: Pharmacology News

Drastically cutting back on caloric intake to lose weight ahead of competition is commonplace among athletes. However, this type of 'dieting' doesn't just diminish performances, it can also compromise their immune systems.

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Ancient Viruses Might Be Spurring Modern-Day Cancers

Drugs.com

FRIDAY, July 19, 2024 -- Cancer growth can be fueled by flecks of ancient viral DNA lodged into the genetics of modern humans, a new study says.Overall, about 8% of the human genome is made of bits of DNA left behind by viruses that infected our.

Virus 111
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How to Transition to a New CDMO Smoothly

Drug Patent Watch

Transitioning to a new Contract Development and Manufacturing Organization (CDMO) can be a complex and challenging process.

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Mechanisms and management of thrombosis in cancer: focus on gastrointestinal malignancies [Minireview]

ASPET

Cancer patients have an increased risk of venous thromboembolism (VTE) which is their second cause of death after disease progression itself. Several thrombotic risk factors coexist in cancer patients, including the ability of both cancer and tumoral microenvironment's cells to directly or indirectly activate platelets and the enzymes of the coagulation cascade, resulting in a hyper-coagulable state of blood.

Therapies 100
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Llama nanobodies: A breakthrough in building HIV immunity

Science Daily: Pharmacology News

Biology researchers have developed a new antibody therapy that can neutralize a wide variety of HIV-1 strains. They found success in an unlikely source -- llamas.

Therapies 126
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Hormone Therapy for Breast Cancer May Lower Dementia Risk

Drugs.com

TUESDAY, July 16, 2024 -- Hormone therapy for breast cancer might reduce a woman’s later risk of dementia and Alzheimer’s disease, a new study finds.Overall, hormone therapy is associated with a 7% lower risk of developing Alzheimer’s or a related d.

Therapies 111