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A surprising new role for a major immune regulator

Broad Institute

MIT biology PhD student Bingxu Liu and Rebecca Carlson PhD ’23, a recent graduate of the Medical Engineering and Medical Physics program through the Harvard-MIT Division of Health Sciences and Technology, are the lead authors of the paper, which appears in Science. Paper Cited Liu B, Carlson R, et al. Human STING is a proton channel.

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Kiromic Announces the Filing of Key European Patents for Its Chimeric PD-1 (chPD1) Target

The Pharma Data

Chimeric PD-1 T-cells also release cytokines to further initiate immune responses to eradicate the tumor cells. is a preclinical stage biopharmaceutical company which is focused on discovering, developing, and commercializing novel immune-oncology applications through its robust product pipeline. About Longwood University.

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Gamma delta T cells: a rising star in cancer therapy

Drug Target Review

These include engineering the cells to express cytokines that promote their maturation and/or differentiation, and engineering drug-resistant γδ T cells that can be combined with chemotherapies, which stress cancer cells but would otherwise also deplete the T-cell population. and MBA students with real-world consulting experiences.

Therapies 105
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Synthetic Origins

Codon

A gene encoding green fluorescent protein was placed alongside one of the three promoters, and as the engineered cells cycled from one gene to the next, they blinked between green—dark—green—dark. These papers became the standard-bearers for a new scientific field: synthetic biology. Another one is immunogenicity.

RNA 57
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Codon Digest: Seeing Colors After Gene Therapy

Codon

.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecular biology and biophysics. a lower risk of immune responses. You can read all of them here.

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Codon Digest: Seeing Colors After Gene Therapy

Codon

.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecular biology and biophysics. a lower risk of immune responses. You can read all of them here.

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The Nobel Prize winning power of click chemistry

Drug Discovery World

José Mejía Oneto , PhD, Founder and CEO at Shasqi, discusses the potential of chemistry to engineer biology to improve the effectiveness of human therapeutics and revolutionise the treatment of disease. What if we could control exactly where drugs went in the body? The possibilities are vast.