DrugBank

OCTOBER 17, 2024

By harnessing the vast amounts of data generated throughout the development pipeline, pharmaceutical companies can accelerate the discovery of novel therapies, optimize clinical trial design, enhance drug safety monitoring, and deliver personalized medicine, ultimately improving patient outcomes and transforming the future of healthcare.

Drug Development 98

Drug Development Metabolic Stability Clinical Trials Drugs 98

Drug Target Review

JUNE 12, 2023

Using the structure properties of existing TEADs – which proved to be ideal in terms of pocket size and shape cavity – the Chemistry42 engine created a novel scaffold that was used as the basis for a number of possible inhibitors. He is an adjunct professor of artificial intelligence at the Buck Institute for Research on Aging.

Metabolic Stability 92

Metabolic Stability Clinical Trials Small Molecule Pharmacokinetics 92

Drug Target Review

JANUARY 16, 2025

11 Macrocycles can also be engineered in other ways to become more cell permeable; for example, by incorporating N-methyl groups in macrocyclic peptides. Pharmaceuticals , 16(7):996, 2023. Cyclic Peptide Design, Chapter 2: Strategies to Enhance Metabolic Stabilities. Angewandte Chemie , 133(15):84668471, 2021.

Drug Development 52

Drug Development Small Molecule Drugs FDA Approval 52