Broad Institute

DECEMBER 13, 2023

Hung Group, Infectious Disease and Microbiome Program Michael Bogaev Princeton University Molecular Biology (major), B.A., Spanish (minor) Genetic Pertubation Platform (GPP) Mohammed Mutaher Harvard University Human Developmental and Regenerative Biology (major), B.A.,

Molecular Biology 52

Molecular Biology Cell Biology Engineering Science 52

Codon

JULY 17, 2024

Backyard astronomers discovered 42 new planets in 2012 , hobbyist paleontologists discovered the world’s largest dinosaur footprint near the Yorkshire coast in 2021, and Sebastian himself open-sourced protocols that make it easier for scientists to engineer plants. And what genes will I need to engineer these flowers?

Laboratories 94

Laboratories Engineering Molecular Biology Science 94

Drug Target Review

MARCH 15, 2024

Advancements in genetic and protein engineering through technology innovation, automation, and more recently machine learning, have led to the development of more complex molecules such as bispecific antibodies and antibody drug conjugates. References Mistry RK, Kelsall E, Sou SN, et al. Budge JD, Knight TJ, Povey J, et al.

Engineering 105

Engineering Molecular Biology Protein Expression Medical Schools 105

Drug Discovery World

NOVEMBER 17, 2022

Lu Rahman selects some recent synthetic biology innovations and the potential they hold to benefit drug discovery. . The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape.

Engineering 130

Engineering Molecular Biology Synthetic Chemistry DNA 130

BMG Labtech

JANUARY 23, 2024

Our knowledge of the deep-sea, the largest biome on Earth, is in its infancy. Water covers more than 70% of the planet and the deep-sea accounts for more than 300 million km 2 of the Earth’s surface. 1,2 Scientists have only scratched the surface of life in the ocean depths but there are intriguing benefits to studying its organisms and ecosystems.

Engineering 52

Engineering Molecular Biology Cell Biology Research 52

Drug Target Review

AUGUST 29, 2024

By simultaneously deleting CD5 and expressing a CD5-targeting CAR into engineered patient T cells, VIPER-101 offers a novel approach for treating T-cell lymphoma. Can you explain the key features and benefits of the Senza5 platform developed by Vittoria Biotherapeutics?

Therapies 59

Therapies Treatment Engineering Molecular Biology 59

Drug Target Review

FEBRUARY 19, 2024

I always found science fascinating, but I really fell in love with it in high school when I was introduced to biochemistry and molecular biology. Biochemistry and molecular biology fascinated me in school. Beate is an elected member of the Board of the Dechema, German Society for Chemical Engineering and Biotechnology.

Molecular Biology 110

Molecular Biology Science Protein Expression Production 110

Drug Discovery World

FEBRUARY 27, 2023

Using foundation models to discover 3D structural targets across various transcripts had massive potential in designing RNA-based medicines. Second, we understood the need to scale up the engineering processes and data collection and increase the number of computational biologists and drug hunters to help validate the platform.

RNA 130

RNA Science Small Molecule Engineering 130

Drug Discovery World

NOVEMBER 1, 2023

Gene editing is a fascinating area of research, as these tools could be used to cure disease or to build models for understanding diseases, but they’re also useful for engineering crops or designing diagnostic tools – there’s such a wide range of applications. DS: What’s been the highlight of your career so far?

Research 148

Research Molecular Biology Science Doctors 148

Broad Institute

AUGUST 7, 2023

MIT biology PhD student Bingxu Liu and Rebecca Carlson PhD ’23, a recent graduate of the Medical Engineering and Medical Physics program through the Harvard-MIT Division of Health Sciences and Technology, are the lead authors of the paper, which appears in Science. Paper Cited Liu B, Carlson R, et al. Human STING is a proton channel.

Regulations 91

Regulations Engineering Clinical Trials DNA 91

addgene Blog

SEPTEMBER 14, 2023

As I left the ivory tower and walked down into its foothills, I began to have conversations with many people who eagerly follow progress in synthetic biology, and want to be involved, but are overwhelmed by its vague and ill-defined contours.

Engineering 108

Engineering Research Molecular Biology 108

Drug Discovery World

MARCH 12, 2024

Secondly, the programme has supported a focus on scientific excellence, which enabled us to release our study on the manufacturing of Velban from our engineered yeast cell factories as a proof-of- concept documenting Biomia’s biosynthesis platform. This has been instrumental for us to critically assess where to play.

Small Molecule 148

Small Molecule Synthetic Chemistry Production Molecular Biology 148

Drug Discovery World

APRIL 11, 2023

The company’s AI-driven 3D RNA structure engine generates RNA structural datasets, integrating machine learning foundation models with experimental wet-lab biology to reveal functional binders to RNA targets. The technology can predict structured, ligandable RNA motifs at high speed and accuracy.

RNA 130

RNA Small Molecule Engineering Disease 130

Drug Discovery World

APRIL 3, 2023

Optimer binders are engineered to overcome these problems. Arron holds a PhD in Molecular Biology and Biophysics from the University of Leeds. Addressing this need in the market has allowed us penetration to work with 75% of the top twenty pharma companies.

Science 130

Science Molecular Biology Therapies Small Molecule 130

Drug Target Review

SEPTEMBER 22, 2023

She received her Doctor of Philosophy in Biochemistry & Molecular Biology at the Graduate University of Chinese Academy of Sciences, Beijing, China, and a Master of Medicine in Toxicology at The Academy of Military Medical Sciences, Beijing, China. Engineering organoids. CMGH [Internet]. 2022;13(1):195–7.

Clinical Research 116

Clinical Research Research Drug Development Molecular Biology 116

Drug Discovery World

JANUARY 26, 2023

“Atomic AI is oriented at the cutting edge of AI, RNA, and structural biology.

RNA 130

RNA Small Molecule Engineering Disease 130

The Pharma Data

MARCH 16, 2022

Johnsson has been Director of the Chemical Biology Department at the Max Planck Institute for Medical Research in Heidelberg since 2017. Prior to taking up this appointment, he was Professor at the Institute of Chemical Sciences and Engineering at EFPL, the Swiss Federal Institute of Technology Lausanne.

Molecular Biology 52

Molecular Biology Cell Biology Science Laboratories 52

The Pharma Data

NOVEMBER 22, 2021

State-of-the-art R&D facility designed to foster collaboration across world-class science ecosystem Sustainable environmental engineering aligned to Company’s zero carbon future. Over the once century, roughly 50 Nobel Prize winners in chemistry and physiology or drug have been associated with Cambridge.

Molecular Biology 52

Molecular Biology Laboratories Engineering Hospitals 52

Elrig

APRIL 6, 2023

Ron discussed three major challenges when developing an organoid model for drug discovery work, as well as taking Artificial Intelligence and neuronal networks full circle, using molecular biology to engineer logic switches in hiPSCs.

Research 40

Research Molecular Biology Science Engineering 40

Drug Target Review

MAY 22, 2024

Secondly, circRNAs can be engineered for more efficient protein expression by carefully selecting and optimising the IRES element, a sequence motif derived from viruses and used to initiate cap-independent translation from circRNA.

Therapies 59

Therapies RNA Protein Expression DNA 59

The Pharma Data

JANUARY 21, 2021

“Finalists are the top young scientists and engineers in the United States who will someday solve some of the world’s most vexing problems. Our most significant philanthropic commitments are in the area of science education, including the Regeneron Science Talent Search and Regeneron International Science and Engineering Fair.

Science 40

Science Engineering Molecular Biology Bioinformatics 40

Drug Discovery World

NOVEMBER 9, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Croasdale-Wood will then participate in a keynote chat, interviewed by Miho.

Engineering 130

Engineering Therapies Protein Production Science 130

The Pharma Data

NOVEMBER 9, 2021

Elias is part of a National Institutes of Health-funded laboratory that focuses on the cell and molecular biology of lung injury and repair. “So in that way, the virus cannot enter into the host system,” said Kamle, a Brown investigator in molecular microbiology and immunology as well as antibody engineering.

Small Molecule 52

Small Molecule Virus Molecular Biology Disease 52

The Pharma Data

JANUARY 4, 2021

Longwood has a robust research department with 7 post doctorates conducting research in molecular biology, microbiology, genomics, cancer biology, and immunology and publishing over 75 publications in different scientific journals in the past 5 years. Barber also serves on Kiromic’s Scientific Advisory Board.

Molecular Biology 40

Molecular Biology Therapies Immune Response Science 40

Drug Discovery World

NOVEMBER 15, 2022

Anita Ramanathan outlines four synthetic biology approaches that are improving and accelerating drug discovery. . It has made its way into almost every aspect of drug discovery, whether it’s exploring basic biology, modelling diseases, identifying and validating targets, or performing drug screens. .

DNA 246

DNA Engineering Drugs Vaccine 246

Drug Target Review

NOVEMBER 8, 2023

Ruella’s research indicated that the removal of CD5 from engineered T cell therapies resulted in increased cytotoxicity and improved anti-tumor efficacy in animal models. By harnessing the fundamental biology of T cells, Senza5 can be used to improve the efficacy of almost any CAR-T therapy.

Therapies 116

Therapies Engineering Molecular Biology Treatment 116

Codon

APRIL 2, 2024

A gene encoding green fluorescent protein was placed alongside one of the three promoters, and as the engineered cells cycled from one gene to the next, they blinked between green—dark—green—dark. These papers became the standard-bearers for a new scientific field: synthetic biology.

RNA 57

RNA Engineering Molecular Biology Synthetic Chemistry 57

Drug Target Review

JUNE 11, 2024

When choosing my bachelor’s degree, the choice was between pursuing a career in biology or in computer science. Biology won that battle, and I pursued a bachelor’s and master’s degree in biochemistry and molecular biology. I had my first scientific encyclopaedia around the age of seven.

Engineering 64

Engineering Science Molecular Biology Doctors 64

Drug Target Review

FEBRUARY 28, 2024

These include engineering the cells to express cytokines that promote their maturation and/or differentiation, and engineering drug-resistant γδ T cells that can be combined with chemotherapies, which stress cancer cells but would otherwise also deplete the T-cell population. and MBA students with real-world consulting experiences.

Therapies 105

Therapies Engineering Molecular Biology Immune Response 105

Codon

DECEMBER 17, 2023

Molecular biology, as the field came to be called 3 , pushed biology from an object of study, driven forward by gentleman scientists and precocious country clergymen, into a tool with which to solve urgent problems. Simple solutions are often the best solutions; no engineering required. Laundry is one example.

Engineering 52

Engineering Molecular Biology Doctors DNA 52

DrugBaron

FEBRUARY 16, 2021

They can exploit their exquisite specificity to carry toxic payloads to specific locations, they can mimic the binding of natural ligands to act as agonists and they can even be engineered into bispecific (or multispecific) formats to hit several targets at once. The fourth milestone in antibody discovery is just beginning to unfold.

Molecular Biology 130

Molecular Biology Small Molecule Engineering Laboratories 130

Drug Discovery World

JANUARY 23, 2023

Increasing interest in CRISPR-Cas gene editing systems over recent years has delivered innovative developments in precision genome engineering technologies, holding enormous potential for applications across the healthcare sector. The success of base editing has led to rapid advances toward commercialisation and clinical application.

Therapies 130

Therapies DNA Engineering RNA 130

Codon

JUNE 18, 2024

When these engineered cells are then placed into a mouse, one can use ultrasound to “hear” the cells as they move around. One can even explode the gas vesicles using high pressure soundwaves, akin to molecular warheads, with astounding implications for medicine. coli cell that had been engineered to express gas vesicles.

Engineering 70

Engineering Laboratories International Clinical Trials 70

Codon

JULY 11, 2023

It is the untouchable foundation of molecular biology. The ribosome is a molecular printer that threads ‘beads’ onto a protein string. The ribosome would then be engineered to ‘hop’ from one codon to the next to build custom proteins. But we will try to convince you that, perhaps, we can do better.

RNA 68

RNA DNA Engineering Laboratories 68

sptlabtech

JUNE 9, 2023

Using our innovative true positive displacement technology, firefly is fully compatible with all molecular biology reagents, viscous and volatile, as well as bead suspension, making it an ideal solution for genomics workflows. What benefits can you expect to see from making the switch to automated liquid handling with firefly?

Laboratories 89

Laboratories Molecular Biology DNA Engineering 89

The Open Targets Blog

APRIL 25, 2023

Although the estate was undoubtedly pretty, the Hall had seen better days and was rather dominated by a 1950s building that provided laboratories for the light engineering company that had owned the site. ranging from university academics through engineers and clerical staff to the military. The same went for analysis tools.

DNA 52

DNA Government Engineering Laboratories 52

Codon

JULY 11, 2023

It is the untouchable foundation of molecular biology. The ribosome is a molecular printer that threads ‘beads’ onto a protein string. The ribosome would then be engineered to ‘hop’ from one codon to the next to build custom proteins. But we will try to convince you that, perhaps, we can do better.

RNA 52

RNA DNA Engineering Laboratories 52