Engineering Molecular Biology Virus 
The Pharma Data
JANUARY 19, 2021
But altering the tracr-L with genetic engineering to make it function more like a guide RNA increased CRISPR-Cas9 cuts. In particular, Editas is known to be exploring tunable CRISPR-Cas9 systems for therapies has developed self-inactivating Cas9 adeno-associated virus vectors. The authors found that tracr-L redirects Cas9 in S.
Broad Institute
AUGUST 7, 2023
STING is primarily on the lookout for DNA, which can indicate either a foreign invader such as a virus or damage to the host tissue or cell. Paul Blainey , the Karl Van Tassel Associate Professor of Biological Engineering at MIT, a core institute member of Broad, and a member of the Koch Institute, is also an author of the paper.
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Codon
FEBRUARY 13, 2024
doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of untreatable, drug-resistant infections.
Codon
JUNE 25, 2024
Kamal Nahas highlights the biological limits on cell division speed and explores how we might engineer cells to grow faster. coli to clone DNA, engineering this microbe to divide more quickly would greatly accelerate research. natriegens proves simpler to engineer than its wild counterpart. This article is part of Issue 03.
The Pharma Data
NOVEMBER 9, 2021
.” The findings not only answer important questions about key mechanisms of the complex SARS-CoV-2 virus, Elias said, but also have direct implications for the development of therapeutics to control the viral infection. “This means there will be less infection in the presence of this therapeutic FRG antibody.”
Drug Target Review
MAY 22, 2024
Secondly, circRNAs can be engineered for more efficient protein expression by carefully selecting and optimising the IRES element, a sequence motif derived from viruses and used to initiate cap-independent translation from circRNA. So far, we have successfully expressed circRNA from six different vector types.
Agency IQ
JANUARY 19, 2024
Prevention of viral contamination is especially important as it may not be apparent that cells have been contaminated with a virus using conventional detection methods. Likewise, the selection of a cell line that was developed using a virus increases the risk of potential viral contamination.
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