Drug Target Review

OCTOBER 6, 2023

Could you explain how CoRegen engineers Tregs to target SRC-3 specifically while maintaining normal Treg functionality in the rest of the body? Our team has created proprietary techniques to engineer Tregs that specifically remove SRC-3 that is expressed in the nucleus. For what indications can this approach be used?

Small Molecule 111

Small Molecule Engineering Protein Expression Therapies 111

Advarra

JANUARY 11, 2024

One strategy proposed the use of synthetic mRNA or modified mRNA analogs, which can enhance the stability and protein expression of mRNA. Monoclonal Antibodies Monoclonal antibodies are lab-engineered immune system proteins.

Vaccine 52

Vaccine Therapies Clinical Trials Small Molecule 52

The Pharma Data

JANUARY 13, 2021

TNX-1500 is a third generation anti-CD40-ligand mAb that has been designed by protein engineering to decrease Fc?RII CD40-ligand is a protein expressed on the surface of activated T lymphocytes that mediates T cell helper function. Second generation anti-CD40-ligand mAbs had dramatically reduced binding to Fc?RII,

Pharmaceuticals 52

Pharmaceuticals Small Molecule Vaccine Protein Expression 52

Alta Sciences

APRIL 17, 2024

They work by binding to specific sequences of nucleotides present within the mRNA structure and can induce mechanisms that either decrease, restore, or modify protein expression. And since proteins are often linked to disease, there's huge potential to treat a broad range of diseases with this technology. Asia, and Europe.

Drug Development 52

Drug Development Treatment FDA Approval Drugs 52

Codon

FEBRUARY 16, 2025

Synthetic biologists have recently designed interacting protein clusters that act as neural networks inside living cells, gene circuits that can switch between OR and AND logic gates based on small molecule triggers , and even programmed a community of cells to execute a hashing function widely used in cryptography.

DNA 80

DNA RNA Engineering Small Molecule 80