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Re-Imagining Med Chem Strategies: the Tyranny of the n+1 Compound

DrugBaron

A lot of resources are therefore poured into synthetic chemistry, and if the compound family is at all synthetically challenging it can require dozens, even hundreds, of chemists to churn out every imaginable variant. We have re-imagined the whole medicinal chemistry strategy.

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Enthera Pharmaceuticals Appoints Kazumi Shiosaki to Its Board of Directors and Lisa Olson to Its Scientific Advisory Board to Push Forward Company Growth and Development

The Pharma Data

Kazumi holds a PhD in Synthetic Chemistry from UC Berkeley. Enthera’s discovery engine and assets are protected by a broad portfolio of patents. She is also a Board member of the Sandford Burnham Prebys Institute. The Company is backed by Sofinnova Partners and JDRF T1D fund. For more information, visit [link]. Source link.

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Synthetic Origins

Codon

A gene encoding green fluorescent protein was placed alongside one of the three promoters, and as the engineered cells cycled from one gene to the next, they blinked between green—dark—green—dark. These papers became the standard-bearers for a new scientific field: synthetic biology. Elowitz: I always liked the term.

RNA 56
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Following our pole star to a transformative collaboration

Dark Matter Blog

Our Chinese CROs are back online and doing synthetic chemistry at a pre-pandemic pace. Our ambition was to unlock vast swaths of valuable biology inaccessible to medicine today because the proteins involved elude our reach. The good news is that plenty of work can continue even with our own lab dormant.

RNA 52