Drug repurposing: The benefits, risks and what we learned from Covid-19
Drug Discovery World
JULY 20, 2023
Pharmacokinetic and pharmacodynamic modelling in mice and allometric scaling should be used to refine dose strengths for human studies, and the available safety data may need re-evaluating considering predicted dosages. However, despite a known safety profile and mechanism of action, the failure rate of 30% is still high.
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