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Repurposing FDA-approved drugs may help combat COVID-19

The Pharma Data

Several FDA-approved drugs – including for type 2 diabetes, hepatitis C and HIV – significantly reduce the ability of the Delta variant of SARS-CoV-2 to replicate in human cells, according to new research led by scientists at Penn State. 25) in the journal Communications Biology.

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De-risking drug discovery with predictive AI

Broad Institute

As of now, papers describing three of these machine learning tools have been published, in the Journal of Chemical Information and Modeling , Molecular Biology of the Cell , and Chemical Research in Toxicology. Molecular Biology of the Cell. A fourth is in the works. DOI: 10.1021/acs.chemrestox.4c00015. Seal S, et al.

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A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic

Broad Institute

The project is a collaboration between the Broad and the African Center of Excellence for Genomics of Infectious Diseases (ACEGID) at Redeemer’s University outside Lagos in Nigeria, where Happi is a professor of molecular biology and genomics. Rural clinics use rapid, low-cost tests to detect a few common pathogens.

Virus 132
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The Promise of Gas Vesicles

Codon

These algae are “one of the most interesting, at least one of the most striking, of the plankton,” wrote Klebahn, who transported the cells back to his laboratory in Hamburg, one hundred kilometers to the south. Light and Sound Progress in biology has long been driven by light. ” During his Ph.D., up to 17 MHz.

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CytoDel Announces Pre-Clinical Data on Cyto-111 as Antidote to Botulinum Neurotoxin (BoNT) Published in Science Translational Medicine

The Pharma Data

Cyto-111 was conceived, expressed and purified in the laboratory of Konstantin Ichtchenko, Ph.D., Standard antibodies cannot access toxin already inside neurons, and thus BAT® (Botulism AntiToxin, a product of Emergent BioSolutions), the only FDA-approved antitoxin, is only effective while the toxin remains in the circulation.

Science 52
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Forty of the Nation’s Most Talented Young Scientists Named Finalists in Regeneron Science Talent Search 2021

The Pharma Data

Founded and led for 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to eight FDA-approved treatments and numerous product candidates in development, all of which were homegrown in our laboratories.

Science 40
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The role of anti-viral drug development in a new pandemic era

Drug Target Review

Investigations into the origins of the COVID-19 pandemic have drawn attention to the risk of researchers potentially becoming infected while working with pathogens in a laboratory 7 and subsequently spreading infections in the broader community. All of these factors are being further accelerated by climate change.