Remove Fragment Screening Remove Pharmacokinetics Remove Therapies
article thumbnail

SARS-CoV-2 main protease. Crowdsourcing, peptidomimetics and fragments

Molecular Design

The SARS-CoV-2 main protease (Mpro) is one of a number of potential targets of interest in the search for COVID-19 therapies. It’s also worth mentioning that fragment screens have been run against SARS-CoV-2 Nsp3 macrodomain at UCSF and Diamond since there are no known inhibitors for this target.