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SARS-CoV-2 Protease Inhibitors: An Attractive Approach for Treating COVID-19

PerkinElmer

Viral protease inhibitors that block enzymes critical for viral replication have long been used in the treatment of human immunodeficiency (HIV) and hepatitis C viruses. Researchers are now studying the potential of protease inhibitors for the treatment of SARS-CoV-2. For research use only. Not for use in diagnostic procedures.

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SARS-CoV-2 main protease. Crowdsourcing, peptidomimetics and fragments

Molecular Design

While I’m not particularly keen on the use of the term ‘open source’ in this context, I have absolutely no quibble with the goal of seeking cures and treatments for diseases that are ignored by commercial drug discovery organizations.