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Target-directed cancer: protein-ligand interactions  

Drug Target Review

We support the drug discovery projects of the CCDD with assay development and screening, biophysics, structural biology and recombinant protein production. With all these diverse methods we characterise protein-ligand interactions in many ways. We can screen with many different formats and modalities.

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Structural Biology

Sygnature Discovery

Fragment Based Drug Discovery Crystallographic fragment screening using a high solubility curated fragment library devoid of soluble aggregates. Curated covalent fragment library also available. Fragment analogs identified for rapid follow-up. PANDDA analysis for rapid delivery of a hit list.

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Sygnature Discovery acquires Peak Proteins

Sygnature Discovery

Sygnature have acquired Peak Proteins Ltd. Following an extensive partnership between the two companies, this deal will enable seamless integration of protein production and related structure determination projects within Sygnature. The Peak Proteins leadership team will also remain with the business.