Broad Institute

NOVEMBER 7, 2023

While RA therapies targeted to specific inflammatory pathways have emerged, only some patients’ symptoms improve with treatment, emphasizing the need for multiple treatment approaches tailored to different disease subtypes. They also found that patients’ CTAPs were dynamic and could change over time in response to treatment.

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Drugs.com

MARCH 21, 2024

THURSDAY, March 21, 2024 -- People with heart disease can stay healthier if they address their emotional problems as well as their physical ailments, a new study says.Treating anxiety and depression reduced ER visits and hospitalizations among.

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Drugs.com

OCTOBER 4, 2024

4, 2024 -- Teens from minority groups seeking treatment at pediatric trauma centers are more likely than their white counterparts to be tested for drugs and alcohol.That's the takeaway from a new study led by researchers at UCLA and. FRIDAY, Oct.

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Drug Discovery Today

MAY 1, 2020

Oxford BioDynamics’ EpiSwitch technology has been chosen as the biomarker platform for prognostic and predictive profiling of COVID-19 patients in the GETAFIX clinical study.Institute of Infection, Immunity and Inflammation, University of Glasgow, and NHS Scotland are leading the effort to identify patients at risk of severe immune complications and (..)

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KIF1A

MAY 29, 2024

Fortunately, Sloane does not currently have epilepsy, and Megan hopes this treatment will prevent it’s onset as her disease progresses. On the day of the treatment, they checked into the hospital where Sloane was administered sedation medication. The post Sloane’s 1st ASO treatment appeared first on KIF1A.

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Broad Institute

OCTOBER 21, 2024

By Leah Eisenstadt October 21, 2024 Credit: Kevin Middleton, Broad Communications In the Bhattacharyya lab, researchers develop methods to quickly identify the most appropriate treatments for bacterial infections. The findings appear in the Journal of Clinical Microbiology. We absolutely couldn’t make these discoveries without them.”

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RNA Hospitals Laboratories Medical Schools 115

Broad Institute

JULY 11, 2024

Targeted drug treatment leads tumor cells to imitate viral infection By Ari Navetta July 11, 2024 Breadcrumb Home Targeted drug treatment leads tumor cells to imitate viral infection Exploiting "viral mimicry," mIDH1 inhibitors trick tumors into thinking they are infected with a virus. paper cited Wu M, Kondo H, et al.

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Treatment Immune Response Virus Drugs 72

Broad Institute

AUGUST 19, 2024

A common fatty acid may help restore healthy vaginal bacteria after infection By Ari Navetta August 19, 2024 Breadcrumb Home A common fatty acid may help restore healthy vaginal bacteria after infection Treatments using oleic acid, a naturally occurring oil used in cells, could improve treatment of recurrent bacterial vaginosis infections.

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Hospitals Treatment Medical Schools Science 121

SCIENMAG: Medicine & Health

NOVEMBER 15, 2023

The Department of Biomedicine at the University of Basel and the University Hospital Basel, today announced that it delivered the first surgical procedure to treat Osteoarthritis (OA) in humans.

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Drugs.com

MAY 20, 2024

MONDAY, May 20, 2024 -- Women treated for infertility were twice as likely as those who conceived naturally to be hospitalized with heart disease within a year of delivery, recent research shows.They are particularly likely to land in the hospital.

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Treatment Hospitals Disease Research 69

Drug Target Review

FEBRUARY 21, 2024

This is a time when several promising treatments – including mRNA vaccines, BiTE therapies and CAR-T cell therapy, are essentially in competition with each other – they all have a common goal of treating the same disease, but they are approaching the objective from different angles.

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The Pharma Data

JUNE 2, 2022

Orencia was one of two immune modulators that improved survival for people hospitalized with COVID-19. Treatment with Orencia versus placebo displayed a strong but not statistically significant improvement in the primary endpoint of time to recovery as measured by day of hospital discharge. People in the Orencia group had 34.2%

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Hospitals Treatment Clinical Trials Disease 52

SCIENMAG: Medicine & Health

AUGUST 15, 2023

By utilizing whole exome sequencing on tumor tissues and their non-tumor counterparts obtained from thirty SA-CRC patients diagnosed at Changzheng Hospital from 2014 to […]

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Research Treatment Hospitals Disease 92

Broad Institute

NOVEMBER 21, 2024

In a study published in Nature Cancer , researchers at the Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute, and Massachusetts General Hospital investigated the evolution of these tumors, many of which are known to be initiated by mutations in an enzyme known as IDH.

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Research Medical Schools DNA Hospitals 124

Common Sense for Drug Policy Blog

JULY 21, 2023

Residential Treatment Compared With Outpatient Treatment Coupled With MOUD "Residential treatment is often considered the highest intensity of treatment for individuals with OUD [ 40 ], and may by particularly important for those with unstable housing, co-morbid mental health conditions, or high medical need [ 41 ].

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Treatment Hospitals Research 52

SCIENMAG: Medicine & Health

JULY 5, 2023

New insights explaining why some children have a longer remission than others after having cutting-edge CAR T-cell therapy for leukaemia have been revealed by researchers at UCL, Great Ormond Street Hospital, and the Wellcome Sanger Institute.

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Treatment Hospitals Therapies Research 69

SCIENMAG: Medicine & Health

SEPTEMBER 22, 2023

A clinical trial has launched to test whether early intensive immune modulation for hospitalized COVID-19 patients with relatively mild illness is beneficial.

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Clinical Trials Hospitals Trials Treatment 52

SCIENMAG: Medicine & Health

AUGUST 21, 2023

Amsterdam, Netherlands – 22 Aug 2023: Recognising and acting on heart attack symptoms is linked with faster life-saving treatment, according to research presented at ESC Congress 2023.1

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Hospitals Treatment Research 72

Science Daily: Pharmacology News

DECEMBER 13, 2023

A new study has shown why many women experience nausea and vomiting during pregnancy -- and why some women, including the Duchess of Cambridge, become so sick they need to be admitted to hospital. The culprit is a hormone produced by the fetus -- a protein known as GDF15.

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Broad Institute

FEBRUARY 16, 2024

The way that clinicians subdivide diabetes patients now is based on symptoms, but in this study, the frequency of genetic risk factors seems to vary among patients with youth-onset T2D,” said Jason Flannick , Broad associate member and assistant professor at Boston Children’s Hospital and Harvard Medical School. “We

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SCIENMAG: Medicine & Health

AUGUST 8, 2023

Some HIV-1 carriers who have received an early antiretroviral treatment during several years are able to control the virus for a long term after treatment interruption. However, the mechanisms enabling this post-treatment control have not been fully elucidated.

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Virus Hospitals Treatment 89

The Pharma Data

APRIL 26, 2022

This action makes Veklury the first approved COVID-19 treatment for children less than 12 years of age. As COVID-19 can cause severe illness in children, some of whom do not currently have a vaccination option, there continues to be a need for safe and effective COVID-19 treatment options for this population,” said Patrizia Cavazzoni, M.D.,

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Drug Target Review

JANUARY 12, 2024

How does the integration of Real-World Data (RWD) with genomic biomarker data contribute to a more comprehensive understanding of disease progression and treatment response? Biomarker information is also useful for tracking progression of the disease and treatment response. This can lead to a new treatment being offered to the patient.

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Drugs.com

SEPTEMBER 27, 2023

experience rapid-fire heartbeats from time to time, and many end up in the hospital for treatment. WEDNESDAY, Sept. 27, 2023 -- Up to 2 million people in the U.S. But an investigational nasal spray may help folks with paroxysmal supraventricular.

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Drug Target Review

AUGUST 29, 2024

However, these treatments will eventually fail for the majority of patients, so there is a strong need for better CAR therapies. How might the CD5 knockout approach impact the treatment of other types of cancers beyond T-cell lymphoma?

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Therapies Treatment Engineering Molecular Biology 59

The Pharma Data

APRIL 26, 2022

— Approval is Supported by Phase 2/3 Data Demonstrating the Safety and Tolerability Profile and Clinical Improvement Outcome in Hospitalized Pediatric Patients Treated with Veklury — Gilead Sciences, Inc. Nasdaq: GILD) today announced that the U.S.

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Treatment Hospitals Science Licensing 52

Broad Institute

OCTOBER 3, 2024

Largest-ever genetic study of epilepsy finds possible therapeutic targets By Ari Navetta October 3, 2024 Breadcrumb Home Largest-ever genetic study of epilepsy finds possible therapeutic targets Scientists have uncovered new genetic links to different types of epilepsy, which could lead to more tailored treatments.

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On Medicine

JANUARY 8, 2024

It takes fresh tissue samples, grows them in the lab as “micro-tumors”, applies different treatments and then takes images through a microscope to measure how well the different treatments work. The eventual aim is to develop a test that can help better match patients to different treatments. The PEAR-TREE study, led by Prof.

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Treatment Hospitals Drugs Research 97

Broad Institute

MARCH 20, 2024

Scientists at the Broad Institute of MIT and Harvard, Brigham and Womens’ Hospital, and Massachusetts General Hospital (MGH) focused on non-small cell lung cancer, the leading cause of cancer death. By Broad and Mass General Communications March 20, 2024 Credit: Chen JH et al. Nature Immunology.

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The Pharma Data

FEBRUARY 24, 2022

Food and Drug Administration approved Jardiance (empagliflozin) to reduce the risk of cardiovascular death and hospitalization for heart failure in adults. Today’s approval will provide a treatment option for a wider range of patients with heart failure,” said Norman Stockbridge, M.D., Today, the U.S.

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FDA Approval FDA Treatment Hospitals 52

Broad Institute

SEPTEMBER 18, 2024

Gram-negative bacteria such as Enterobacteriaceae are a common cause of these infections and have few treatment options. Researchers at Keio University School of Medicine in Tokyo and the Broad Institute of MIT and Harvard have isolated 18 bacterial strains from stool from healthy people that could potentially be a more effective treatment.

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Medical Schools Disease Hospitals Treatment 119

PLOS: DNA Science

SEPTEMBER 5, 2024

Diagnosis began to shift from a body-part basis to a molecular one, which I wrote about in “Mutation and location important in cancer treatment” for The Lancet in 2015. These findings can then be used to predict response to treatments as well as survival time.

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Treatment FDA Approval DNA Small Molecule 64

Broad Institute

JANUARY 30, 2024

In others, an infection can cause the immune system to spin out of control, leading to sepsis — organ dysfunction that lacks effective treatments and is often fatal. For his medical residency, he moved to Massachusetts General Hospital, where he was enthralled with seeing patients, especially the ones with perplexing infections.

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Hospitals Medical Schools Virus Science 137

The Pharma Data

MARCH 9, 2022

Treatment-emergent adverse events were comparable between PAXLOVID (23%) and placebo (24%), most of which were mild in intensity. million treatment courses delivered thus far and 30 million expected by July to help combat this devastating disease.

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Drugs.com

MARCH 25, 2024

MONDAY, March 25, 2024 — Men with prostate cancer treated at hospitals participating in a special drug-pricing program were more likely to stick to their therapy than patients elsewhere, new research reveals.The federal 340B Drug Program requires.

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Treatment Hospitals Therapies Research 59

Drugs.com

OCTOBER 8, 2024

8, 2024 -- AI isn’t ready to run a hospital’s emergency room just yet, a new study concludes.ChatGPT likely would ask for unnecessary x-rays and antibiotics for some patients, and admit others who don’t really need hospital treatment. TUESDAY, Oct.

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Drug Target Review

NOVEMBER 2, 2023

Scientists from Nationwide Children’s Hospital discovered an alternate origin of brain mosaicism in some children with focal epilepsy. Dr Adam Ostendorf, a paediatric neurologist at Nationwide Children’s Hospital and an author of the study said: “About one in every 26 people will have epilepsy at some point in their lives.

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