The Pharma Data

SEPTEMBER 28, 2020

The UK’s first hospital trust to record 1,000 Covid-19 deaths says the toll is the “terrible reality” of the virus. University Hospitals Birmingham, which has four hospitals and is the biggest trust in England, had reported 1,001 deaths since 14 March as of Sunday. Coronavirus pandemic.

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Science Daily: Pharmacology News

DECEMBER 14, 2023

New research comparing the viruses that cause the flu and COVID-19 shows that people hospitalized with seasonal influenza also can suffer long-term, negative health effects, especially involving their lungs and airways.

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Broad Institute

JUNE 18, 2024

Simple test for flu could improve diagnosis and surveillance By Allessandra DiCorato June 18, 2024 Breadcrumb Home Simple test for flu could improve diagnosis and surveillance A low-cost CRISPR-based paper strip test distinguishes between influenza types and can be reprogrammed to recognize different viruses including the H5N1 bird flu virus.

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The Pharma Data

APRIL 8, 2022

Using a Human Lung Chip that replicates the structures and functions of the lung air sac, or “alveolus,” the research team discovered that applying mechanical forces that mimic breathing motions suppresses influenza virus replication by activating protective innate immune responses. . During his Ph.D.

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Drug Discovery World

OCTOBER 17, 2023

In May 2015, the Department of Interventional Oncology of Renji Hospital in Shanghai collaborated with CARsgen Therapeutics to initiate the first clinical study with CAR T cell therapy targeting the GPC3 (Glypican-3) protein in advanced hepatocellular carcinoma.

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SCIENMAG: Medicine & Health

JULY 13, 2023

As a result of the COVID-19 pandemic, respiratory syncytial virus (RSV) surges in young children occurred outside the usual November to March season, when immune-based prophylactic is available to protect children at high risk for severe illness.

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The Pharma Data

AUGUST 13, 2020

The number of people in hospital with Covid-19 fell in coronavirus hotspots in June and July, according to data released by NHS England. But scientists use hospital data to understand whether rising cases reflect more infections or more testing. More of these cases are among young people, who are less likely to become seriously sick.

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The Pharma Data

AUGUST 24, 2020

They say genome sequencing shows the two strains of the virus are “clearly different”, making it the world’s first proven case of reinfection. Those infected develop an immune response as their bodies fight off the virus which helps to protect them against it returning.

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The Pharma Data

SEPTEMBER 18, 2020

Cases of the virus and hospital admissions for Covid-19 are thought to be doubling every seven to eight days in the UK. And the scientist behind the Covid Symptom Study app said it appeared to be “the start of a second wave” The developments come as new England-wide restrictions are being discussed. At least 13.5

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Drug Discovery World

AUGUST 23, 2023

The US Food and Drug Administration (FDA) has approved the first vaccine for pregnant individuals to prevent respiratory syncytial virus (RSV) in infants.

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Drug Discovery World

JUNE 6, 2024

The global Phase III clinical trial is being led by University College London Hospitals NHS Foundation Trust in the UK and will include around 1,100 people. Moderna recently secured FDA approval for the first mRNA vaccine to treat something other than Covid-19 – it’s respiratory syncytial virus (RSV) vaccine mRESVIA (mRNA-1345).

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The Pharma Data

SEPTEMBER 4, 2020

The main test used to diagnose coronavirus is so sensitive it could be picking up fragments of dead virus from old infections, scientists say. He believes the detection of traces of old virus could partly explain why the number of cases is rising while hospital admissions remain stable. Image copyright. Getty Images.

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The Pharma Data

AUGUST 7, 2020

Individuals in hospitals and care homes are not included in the ONS survey, which has been estimating cases in private households since May. This means there are stricter rules on socialising for people living in these areas and for businesses, in order to control the spread of the virus. Source link.

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Drug Discovery World

AUGUST 24, 2022

It will also assess the time taken until throat and lesion swabs test negative for monkeypox virus and the proportion of patients who require hospitalisation due to complications from the disease. . Tecovirimat prevents the Monkeypox virus from leaving infected cells, helping stop its spread within the body.

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The Pharma Data

DECEMBER 9, 2020

9, 2020 — In a sign that the COVID-19 pandemic is entering its most dire stage yet, new federal data show that more than a third of Americans now live in areas where hospitals are critically short of intensive care beds. WEDNESDAY, Dec. When you don’t have that capacity, that means people will die.”

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SCIENMAG: Medicine & Health

JANUARY 16, 2024

In early 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a highly contagious and pathogenic virus, made its alarming debut and quickly spread worldwide, causing the novel coronavirus (COVID-19) pandemic that threatened human health and public safety.

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The Pharma Data

JUNE 7, 2023

RSV is a common, contagious respiratory virus that leads to over 270,000 hospitalisations and approximately 20,000 in-hospital deaths each year in adults aged 60 years and over in Europe. The authorisation is based on GSK’s landmark positive pivotal AReSVi-006 (Adult Respiratory Syncytial Virus) phase III trial data.

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Drug Discovery World

OCTOBER 13, 2023

The project involves teams from the University Hospitals of Derby and Burton NHS Foundation Trust and the University of Exeter, in collaboration with Gilead Sciences. A UK-based study will investigate whether a common anti-viral medication could double up as a treatment for long Covid.

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Broad Institute

FEBRUARY 8, 2024

By Allessandra DiCorato February 8, 2024 Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland Scanning electron image of the Lassa virus budding off a cell. Other scientists had discovered that this gene was critical for the Lassa virus to enter cells.

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The Pharma Data

JANUARY 29, 2021

SARS-CoV-2 Seroconversion Tied to Out-of-Hospital Sudden Deaths. from Lenox Hill Hospital in New York City, and colleagues examined the association between OHSD and SARS-CoV-2 epidemiologic burden during the first wave of the COVID-19 pandemic across neighborhoods of NYC. Professional. FRIDAY, Jan. FRIDAY, Jan. Coleman, R.N.,

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The Pharma Data

DECEMBER 1, 2020

1, 2020 — Yet another grim record for COVID-19 hospitalizations was set on Monday, as more than 96,000 patients battled severe cases of the virus in hospital wards across America. But the number of hospitalizations have risen by more than 12 percent over the past week, the newspaper noted. TUESDAY, Dec.

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Drug Discovery World

JUNE 23, 2023

The Food and Drug Administration (FDA) has granted accelerated approval to Elevidys (delandistrogene moxeparvovec-rokl), an adeno-associated virus (AAV) based gene therapy for the treatment of DMD. Sarepta Therapeutics’ Elevidys has become the first gene therapy for Duchenne muscular dystrophy (DMD) to gain marketing authorisation in the US.

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The Pharma Data

MARCH 23, 2022

“When the COVID-19 pandemic started, our multidisciplinary research teams switched our investigations of other viruses and bacteria to focus on a potential treatment for what was then a challenging new virus for us,” says Children’s Center microbiologist Lori Jones-Brando, Ph.D., alone each year.

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Drug Discovery World

JULY 7, 2023

They found that patients with more frequent antibiotic exposure in the past three years were at higher odds of experiencing severe Covid-19 outcomes, including hospital admission and 30-day mortality. Plus, using a range of antibiotics was more likely to be associated with Covid-19 hospital admission.

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The Pharma Data

SEPTEMBER 10, 2020

The disruption to hospitals in England during the pandemic has meant the number of patients facing long waits for routine operations has soared. But there are some encouraging signs, with treatments happening in hospitals on the increase. Image copyright. Getty Images. Image copyright. Getty Images.

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The Pharma Data

MAY 16, 2022

million symptomatic cases of the virus, as well as 690,000 hospitalizations and more than 110,000 deaths. The profound health and economic impact of the Pfizer-BioNTech vaccine during its first year of rollout in the US is described in detail in a new study in the peer-reviewed Journal of Medical Economics.

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Drug Discovery World

AUGUST 31, 2022

The study authors suggest that antigen levels could help determine those patients most likely to benefit from therapies directed at fighting the virus. . Analysis of Covid patient blood samples. High blood antigen levels also correlated with some known risk factors for worse illness, such as being male.

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Drug Discovery World

SEPTEMBER 13, 2023

The results The study shows that over 80% of the patients hospitalised in a psychiatry department near Paris during the first wave of the Covid-19 pandemic had been exposed to SARS-CoV-2, which was 1.6 times more than the control group.

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The Pharma Data

DECEMBER 29, 2020

29, 2020 /PRNewswire/ — Phase 3 program in hospitalized patients to continue based on passing futility analysis on ability to reduce incidence of death or mechanical ventilation. First antibody therapy to demonstrate anti-viral effect in patients hospitalized with COVID-19. TARRYTOWN, N.Y. , Regeneron Pharmaceuticals, Inc.

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Drug Discovery World

JANUARY 11, 2024

Messenger RNA therapies are also currently being investigated in other rare inherited metabolic diseases – propionic and methylmalonic acidaemias – in global clinical trials sponsored by Moderna, including at Great Ormond Street Hospital for Children. mRNA contains instructions that direct the cells to make proteins.

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The Pharma Data

DECEMBER 3, 2020

Another record-breaking day of COVID-19 hospitalizations and deaths underscored Redfield’s grim warning. The number of people hospitalized for COVID-19 on Wednesday passed 100,000, nearly double the highest point seen last spring. With hospitals filling up in multiple states, the days ahead do appear bleak.

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Drug Discovery World

JULY 3, 2023

In the Modulating Tumour Microenvironment programme, experts took a deeper look at the results we are seeing from emerging immunotherapies such as immune checkpoint blockade and chimeric antigen receptor T cells (CAR Ts), and also discussed advances in our understanding of and strategies to modulate the tumour microenvironment.

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The Pharma Data

DECEMBER 17, 2020

(NASDAQ: REGN ) today announced that the New England Journal of Medicine (NEJM) has published initial clinical data from an ongoing seamless Phase 1/2/3 trial of the antibody cocktail casirivimab and imdevimab in non-hospitalized patients with COVID-19. “The investigational cocktail is now available to indicated high-risk U.S.

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Drug Discovery World

FEBRUARY 5, 2024

Science and technology innovator Danaher launched a strategic collaboration with Cincinnati Children’s Hospital Medical Center, with the goal of improving patient safety by addressing a leading cause of failure in clinical trials.

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Drug Discovery World

MAY 25, 2023

Combining skills, expertise, and facilities to respond to high consequence viruses at CVR-CRUSH Drug-Screening and Resistance Hub The day’s final presentation was from Agnieszka Szemiel, Facility Manager at the University of Glasgow, who discussed CRUSH, part of the Centre for Virus Research (CVR) based at University of Glasgow.

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The Pharma Data

OCTOBER 30, 2020

(NASDAQ: REGN) received today a recommendation from the independent data monitoring committee (IDMC) for the REGN-COV2 antibody cocktail treatment trials for COVID-19 that the current hospitalized patient trial be modified. About the REGN-COV2 Trial in Hospitalized Patients. Cohort 1A: patients not requiring oxygen.

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Drug Discovery World

OCTOBER 31, 2022

The researchers suggest that non-pharmaceutical interventions, including masks, prophylactic antibody treatment, and anti-viral treatment after acquisition of the virus are important tools to consider for additional protection against severe Covid-19 in immunocompromised adults. . Lower protection despite boosters .

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