The Pharma Data

NOVEMBER 20, 2020

The clinical evidence from Regeneron’s outpatient trial suggests that monoclonal antibodies such as casirivimab and imdevimab have the greatest benefit when given early after diagnosis and in patients who have not yet mounted their own immune response or who have high viral load.

Therapies 52

Therapies FDA Clinical Trials Hospitals 52

Codon

APRIL 2, 2024

But in those early years, everything in the laboratory was so slow and difficult. AP: We can’t even grow most types of cells in the laboratory. Like, if we start thinking about therapeutic circuits, how can we design the components in such a way that they are not going to cause an immune response? Elowitz: Exactly.

RNA 56

RNA Engineering Molecular Biology Synthetic Chemistry 56

The Pharma Data

DECEMBER 17, 2020

Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to eight FDA-approved treatments and numerous product candidates in development, all of which were homegrown in our laboratories.

Hospitals 52

Hospitals Production Clinical Trials Virus 52

The Pharma Data

NOVEMBER 21, 2020

The clinical evidence from Regeneron’s outpatient trial suggests that monoclonal antibodies such as REGEN-COV2 have the greatest benefit when given early after diagnosis and in patients who have not yet mounted their own immune response or who have high viral load.

FDA 40

FDA Clinical Trials Hospitals Production 40

Agency IQ

APRIL 12, 2024

The regulations also explain that this trait can be demonstrated via appropriate laboratory tests or adequately controlled clinical data. Overall, potency—while critical to product integrity—is just one component which the agency uses to assess product quality, alongside identity, strength and purity.

Production 40

Production FDA Therapies Biochemical Assays 40

Codon

OCTOBER 27, 2024

However, the red-painted bacteria are only visible under a microscope, so healthcare workers must transport the samples to a laboratory to determine the results. Other TB tests exist, but most also rely on laboratory access. Other TB tests exist, but most also rely on laboratory access. A sputum test stain for M. tuberculosis.

Immune Response 89

Immune Response Doctors Disease Laboratories 89

Codon

APRIL 23, 2023

Most people would take the two CRISPR gene-editing components (a Cas9 protein and guide RNA), package them up inside of a virus, and then inject the viruses into the skulls of mice. Unfortunately, they can also trigger immune responses, and they are not super efficient at gene-editing some parts of the brain.

Vaccine 52

Vaccine DNA Virus Engineering 52

Codon

APRIL 23, 2023

Most people would take the two CRISPR gene-editing components (a Cas9 protein and guide RNA), package them up inside of a virus, and then inject the viruses into the skulls of mice. Unfortunately, they can also trigger immune responses, and they are not super efficient at gene-editing some parts of the brain.

Vaccine 52

Vaccine DNA Virus Engineering 52