Immune Response Laboratories RNA 
Drug Target Review
JANUARY 2, 2024
In research published in Scientific Reports , 1 investigators focused on mesenchymal stem cells (MSCs), known for their potential in treating cell defects and regulating immune responses. The experiment comprised two components: computational methodology development and laboratory experiments.
Codon
NOVEMBER 3, 2024
Working at the famed Pasteur Institute, the duo began by figuring out how best to culture mycobacteria — a seemingly simple, but essential first step, given how no one at the time had yet come up with an effective way of growing these bacteria in the laboratory. tuberculosis. Many more could emerge as machine learning tools improve.
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Drug Target Review
DECEMBER 7, 2023
Researchers from the Laboratory of Bacteriology at The Rockefeller University have now found that bacteria sense phages by a defensive response named CBASS (cyclic oligonucleotide-based antiphage signalling system) which detects viral RNA. In bacteria , cGAS-like cyclases are central parts of the CBASS immune response.
PLOS: DNA Science
MAY 16, 2024
That’s thanks to accelerated genome sequencing technologies, expanded laboratory capabilities, and interacting infrastructure on a global level. As soon as the initial RNA genome sequence of the pathogen that would be named SARS-CoV-2 was published, CDC and other organizations began developing diagnostic tests.
Codon
AUGUST 27, 2024
When doctors sequenced the DNA and RNA found in Alice’s blood and synovial fluid—the liquid that surrounds and lubricates joints—they found abnormally low levels of genes encoding iron-storing proteins and high levels of epidermal growth factor receptor RNA. At least nine laboratories outside the U.S.
Broad Institute
JUNE 27, 2024
CRISPRoff silences the targeted gene by adding methyl groups, chemical tags that prevent the gene from being transcribed or read into RNA and so from being expressed as protein. ZFPs are also common in human cells, meaning they are less likely to trigger an immune response against themselves than the bacterial Cas9.
Codon
DECEMBER 12, 2024
DNA and RNA molecules are also built from exclusively right-handed nucleic acids. Across the tree of life, organisms strictly require exactly one of the two chiral forms of their molecular building blocks — amino acids, nucleotides of RNA and DNA. 4 As far as we know, right-handed proteins never occur naturally.
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