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Phage have been of interest to scientists as tools to understand fundamental molecularbiology, as vectors of horizontal gene transfer and drivers of bacterial evolution, as sources of diagnostic and genetic tools, and as novel therapeutic agents. In bacteria , cGAS-like cyclases are central parts of the CBASS immuneresponse.
But as molecularbiology has advanced, so too has our approach to finding new drugs. Another promising avenue is the use of technologies like RNA interference and gene editing, which allow scientists to turn off the production of certain proteins altogether. This method was more about serendipity than science.
The only subject in school that held my interest was biology. As soon as I learned about DNA and RNA, I wanted to be a molecular biologist. I wanted to use molecularbiology to create drugs. Last stops at RNA My last roles in biotech were where my original passion began: DNA and RNA.
The central dogma of molecularbiology is that information generally (with few exceptions) flows from DNA to RNA to Protein. Build your social immunity. The adaptive immuneresponse identifies and responds to highly specific antigens associated with infections and cancer. Remember life’s Central Dogma.
I was reading a lot of molecularbiology papers about different systems, especially circadian clocks, and also a book called Biological Feedback , by Thomas and D’Ari, that sketched out really simple models for different kinds of feedback circuits. The exported RNA could transfect just the target cell.
.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecularbiology and biophysics. How do transcription factors couple up with the correct RNA molecule?
.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecularbiology and biophysics. How do transcription factors couple up with the correct RNA molecule?
Isselbacher Professor of Medicine at Harvard Medical School, director of the Center for Computational and Integrative Biology and member of the Department of MolecularBiology at MGH, and co-director of the Center for Microbiome Informatics and Therapeutics at MIT.
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