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Unlocking Undruggable Targets: Shifting Paradigms in Modern Drug Discovery

DrugBank

This method was more about serendipity than science. But as molecular biology has advanced, so too has our approach to finding new drugs. Their size and mode of action allow for a broader interaction with target molecules, which can be advantageous in disrupting protein-protein interactions or modulating immune responses.

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A surprising new role for a major immune regulator

Broad Institute

MIT biology PhD student Bingxu Liu and Rebecca Carlson PhD ’23, a recent graduate of the Medical Engineering and Medical Physics program through the Harvard-MIT Division of Health Sciences and Technology, are the lead authors of the paper, which appears in Science. Paper Cited Liu B, Carlson R, et al. Online August 3, 2023.

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A Molecular Biologist’s Advice For Life

LifeSciVC

One thread that has run throughout it has been my passion for science as a lens for looking at the world. In particular, I love connecting science to daily life. Pfizer’s recent campaign around “ Science Will Win ” similarly appealed to the ethos of the power of science to help humanity. Remember life’s Central Dogma.

Science 86
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My Attendance at the 2024 Boston Society Cell and Gene Therapy Conference

Alta Sciences

via Wikimedia Commons My fellow Altascientists and I recently attended the 2024 annual Boston Society Gene & Cell Therapy Conference , held at the wonderful Museum of Science in, of course, Boston, MA. Contact one of our experts today to discuss your gene therapy program.

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Gamma delta T cells: a rising star in cancer therapy

Drug Target Review

from 2003 to 2006, covering the biotechnology and life-science tools sectors. Earlier in his career, Mr Ho was responsible for FP&A and operational analysis at CuraGen Corporation and worked as an Associate on the Healthcare Investment Banking team at Cowen, Inc. gammadelta T cells link innate and adaptive immune responses.

Therapies 105
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Scaling Phage Therapy

Codon

doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of untreatable, drug-resistant infections.

Therapies 129
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Roche launches new quantitative antibody test to measure SARS-CoV-2 antibodies, to support the evaluation of vaccines

The Pharma Data

The Elecsys Anti-SARS-CoV-2 serology test can be used to quantitatively measure antibodies in people who have been exposed to the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and can play an important part in characterising a vaccine-induced immune response. The molecular biology of coronaviruses.

Vaccine 52