The Pharma Data

AUGUST 16, 2021

Better activation of innate and adaptive immune responses was achieved with CV2CoV, resulting in faster response onset, higher titers of antibodies, and stronger memory B and T cell activation as compared to the first-generation candidate, CVnCoV. “In Induction of innate immunity was investigated via specific cytokine markers.

Immune Response 52

Immune Response Vaccine Virus RNA 52

Broad Institute

JUNE 27, 2024

By Greta Friar, Whitehead Institute June 27, 2024 Images of a mouse brain show the effect of a technology called CHARM in turning off the expression of a gene in the brain. Like Cas9, ZFPs can serve as guide proteins to direct the tool to a target site in DNA. Credit: Neumann EN, Bertozzi TM, et al.

Disease 142

Disease Therapies Clinical Trials Engineering 142

PerkinElmer

AUGUST 25, 2019

1 AlphaLISA ® Assay Technology Studies done using human tumor cell lines by PerkinElmer Application Scientist Jeanine Hinterneder have contributed to our understanding of how tumor cells develop the ability to evade the immune response. When that occurs the cancer becomes more severe.

Protein Expression 52

Protein Expression Immune Response Treatment Research 52

Advarra

JANUARY 11, 2024

mRNA Cancer Vaccines mRNA cancer vaccines represent a newer class of vaccines utilizing mRNA’s ability to encode for almost any protein, while maintaining an acceptable safety profile with flexible delivery and production processes.

Vaccine 52

Vaccine Therapies Clinical Trials Small Molecule 52

The Pharma Data

MARCH 26, 2021

PD-L1 is a protein expressed on tumour cells and tumour-infiltrating cells, which suppresses the immune response and enables tumour cells to avoid detection by binding to proteins on the surface of immune cells. Median OS in the Tecentriq arm was the same as observed at the previous analysis (20.2

Treatment 52

Treatment Therapies Protein Expression Immune Response 52

The Pharma Data

MAY 4, 2021

PD-L1 is a protein expressed on tumour cells and tumour-infiltrating cells, which suppresses the immune response and enables tumour cells to avoid detection by binding to proteins on the surface of immune cells. Median OS in the Tecentriq arm was the same as observed at the previous analysis (20.2

Treatment 52

Treatment Therapies Disease Pharmaceuticals 52

Codon

APRIL 9, 2023

AI + Bio *Transfer learning for cross-context prediction of protein expression from 5’UTR sequence. Read Combinatorial gene therapy for epilepsy: Gene sequence positioning and AAV serotype influence expression and inhibitory effect on seizures. Biology is the world’s most advanced technology. Subscribe to learn more.

Therapies 52

Therapies RNA Engineering Vaccine 52