The Pharma Data

MARCH 23, 2022

To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase. Polymerase is a viral protein that directs how Ebola virus replicates its genome as it infects new hosts. Drugs that target polymerase could potentially treat Ebola virus infections and save lives.

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PLOS: DNA Science

MAY 16, 2024

A Novel Virus Appears In retrospect, everything unfolded with astonishing speed. Did it there either recombine with another virus on its own, or inspire a manipulation of another virus of a key part of the spike gene, seeding the pandemic through a “lab leak?” Work on vaccines ensued too.

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Broad Institute

APRIL 25, 2024

It can take only 36 hours for a virus that is emerging in a very remote place to find itself in New York or Paris — they are just a few flights away,” Happi said. Since 2007, they’d been studying Lassa fever, an often deadly illness caused by infection with the Lassa virus, which is endemic in West Africa.

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SCIENMAG: Medicine & Health

MARCH 7, 2024

Bettina Stark-Watzinger, Germany’s Federal Minister of Education and Research, emphasizes: “The rapid and successful development of active substances against the SARS-CoV-2 virus illustrated the importance of good and trusting international cooperation among scientists, especially in the field of integrated structural biology.

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DrugBaron

APRIL 13, 2020

More than a month after the World Health Organisation declared COVID19 a global pandemic on 11th March we are still missing one crucial piece of data from our modelling: the fraction of people who have established productive immunity against the SARS-CoV2 virus.

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Drug Target Review

JUNE 1, 2023

La Jolla Institute for Immunology (LJI), US, scientists demonstrated how antibodies obtained from a clinical study participant attach to the SARS-CoV-2 spike protein and neutralise the virus. The vaccine prompts the body to produce the spike protein, which allows the immune system to develop antibodies against the real virus.

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PLOS: DNA Science

JULY 27, 2023

That information led, thanks to vaccine shelved from the first SARS circa 2003, to the rapid development and deployment of mRNA vaccines against the new infectious disease. The owners of the felines all reported feeding their pets raw meat, and samples of the meat revealed not only flu virus genetic material, but also infectious virus.

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The Pharma Data

MARCH 3, 2022

The FDA decision is informed by the results of the Phase 2b proof-of-concept study of RSVpreF (NCT04032093), a global, double-blinded, placebo-controlled study that assessed the safety and immunogenicity of RSVpreF in healthy pregnant women ages 18 through 49 years old, who were vaccinated between 28- and 36-weeks gestation, and their infants. “If

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The Pharma Data

JANUARY 21, 2021

President Joe Biden has promised to re-energize the nation’s response to COVID-19, but one of his top pandemic advisors says that effort could be hamstrung by both the virus and the failings of the previous administration. Further Support and Information on COVID-19. © 2021 HealthDay. All rights reserved. Posted: January 2021.

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Broad Institute

MARCH 22, 2024

Staying power The mRNA in today’s COVID vaccines is so effective because very little is needed – once injected into the body, it stimulates the production of proteins that resemble parts of the COVID virus.

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Engineering Protein Production RNA Vaccine 140

Broad Institute

MAY 16, 2024

But even when this approach succeeds, the candidates often don’t work in other species, and the approach doesn’t provide information about how the AAVs reach their targets. Gene therapy could potentially treat a range of severe genetic brain disorders, which currently have no cures and few treatment options.

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Drug Target Review

JANUARY 26, 2024

These ACE2-coated particles could be tested as an anti-viral therapeutic, and as sensors for detecting virus particles. To find a DNA fragment that contained the intact ACE2 gene, complete with its embedded regulatory information, they searched libraries of cloned DNA fragments generated as part of the Human Genome Project.

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Codon

FEBRUARY 13, 2024

doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of untreatable, drug-resistant infections.

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Codon

SEPTEMBER 29, 2024

The systems themselves began to infer the existence of unknown biological modalities, extracting information from data never explicitly fed to them. On the surface, they hadn't deviated much from the early 2020s: a virus infected a cell and released the genetic therapy hidden within. It started small.

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Broad Institute

JANUARY 30, 2024

Every question that I've chosen to pursue in my lab today is deeply informed by what I’ve seen in the clinic,” he said. "I RESEARCH, INTERRUPTED When Bhattacharyya first heard rumblings about the new respiratory virus spreading overseas in early 2020, his lab had only one other member, a research assistant.

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Alta Sciences

SEPTEMBER 20, 2023

AnQlar is a nanoparticle intended to help prevent the spread of negatively charged viruses such as COVID-19 and influenza via intranasal spray, and has been shown to inhibit the ability of the virus to replicate at non-toxic concentrations. For more information, please visit virpaxpharma.com or follow on Twitter, LinkedIn, and YouTube.

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Broad Institute

DECEMBER 13, 2023

In their study, the researchers focused on a variant of an engineered recombinant adeno-associated virus (rAAV) known as PHP.eB. The virus can cross the blood-brain barrier, but there was no systematic and quantitative knowledge about how well this vector delivers its cargo to particular cell types and brain subregions.

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DNA Virus Research Engineering 140

DrugBaron

MAY 24, 2021

Because of their remit, to look at the best way of reducing the impact of the virus, they have set out the best way, in their view, to achieve that narrow goal. Arguably, if everyone in the country stayed in complete isolation for a month, the virus would disappear altogether with every transmission chain hitting a brick wall simultaneously.

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NIH Director's Blog: Drug Discovery

NOVEMBER 5, 2020

Because SARS-CoV-2 is so highly infectious, basic researchers without access to specially designed biosafety facilities may be limited in their ability to study the virus. While the quantum dots may bind and enter human cells just like the virus, they can’t cause an infection. But these harmless quantum dots offer a safe workaround.

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Research Laboratories Laboratories Science Drugs 85

Drug Target Review

JANUARY 15, 2024

CD8+ T cells are a type of lymphocyte that specialises in scanning information presented by HLA Class I. This produces a great advantage in infectious disease, as it becomes difficult for a virus to adapt and spread from person to person, because each person’s HLA array is genetically distinct.

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The Pharma Data

FEBRUARY 1, 2021

1, 2021 – The National Institutes of Health has launched a new database to collect information and biospecimens from people who have experienced neurological problems associated with severe acute respiratory syndrome coronavirus 2 infection. ” More Information. ” More Information. MONDAY, Feb. © 2021 HealthDay. .

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The Pharma Data

JANUARY 26, 2021

The person is being interviewed for more information about their illness, travel, and contacts, the Associated Press reported. “We know that even as we work hard to defeat COVID-19, the virus continues to evolve as all viruses do,” Minnesota Health Commissioner Jan Malcolm said in a statement. Associated Press Article.

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FDA Law Blog: Drug Discovery

DECEMBER 7, 2022

We know, for example, the use of viral vectors results in antibody production that could inhibit future administration of gene therapies using the same or similar viruses, which will inform treatment decisions by patients with their doctors.

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Codon

AUGUST 27, 2024

While reading all the sequences present in a sample, researchers want to find any that are out of place, such as those that belong to a never-before-seen virus. This cleaning, annotation, and characterization work is all performed computationally.

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DNA Laboratories Hospitals Virus 96

NIH Director's Blog: Drug Development

MARCH 18, 2021

Yet they are the source for many of the viruses that have spilled over into humans with devastating effect, including rabies, Ebola virus, Nipah and Hendra viruses, severe acute respiratory syndrome coronavirus (SARS-CoV), and, likely, SARS-CoV-2. Despite carrying all of these viruses, bats rarely show symptoms of being sick. 2021 Jan 14.

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The Pharma Data

DECEMBER 16, 2020

Most experts believe the severe acute respiratory syndrome coronavirus 2 virus originated in animals in China, probably bats, the Associated Press reported. Tracking down the animal in which the virus emerged will be key, so the group will take samples of further bat species and other animals that might harbor it. WEDNESDAY, Dec.

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The Pharma Data

DECEMBER 16, 2020

Most experts believe the SARS-CoV-2 virus originated in animals in China, probably bats, the Associated Press reported. The objective of the 10-person WHO team is to gather information to better prepare for possible future outbreaks, according to team member Fabian Leendertz, a German biologist who specializes in emerging diseases.

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Advarra

JUNE 13, 2024

The following information includes common elements to consider in site hazard communications and use of this “bundling” approach to simplify things for stakeholders (this is the approach Advarra’s IBC has taken). This means site personnel do not have to review and sign a new SOP each time they submit a new mRNA protocol.

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The Pharma Data

JANUARY 11, 2021

The COVID-19 vaccines work by teaching the immune system to protect against the virus, experts said. Neither of the two vaccines approved in the United States — made by Pfizer-BioNTech and Moderna — contains the live virus. This is because it’s not known how long immunity to the virus lasts after an infection.

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The Pharma Data

JANUARY 15, 2021

However, the researchers said that even if a previously infected person has immunity, they may still be able to carry the virus and infect others. “We now know that most of those who have had the virus, and developed antibodies, are protected from reinfection, but this is not total and we do not yet know how long protection lasts. .

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Virus Vaccine Research 52

The Pharma Data

JANUARY 11, 2021

The exact origins of the virus remain unclear, but a leading theory is that it was carried by bats and passed to humans through an intermediary species of animal, sold as food or medicine in traditional Chinese “wet markets.” Further Support and Information on COVID-19. ” Associated Press Article. © 2021 HealthDay.

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The Pharma Data

FEBRUARY 25, 2021

5 To date, ticks infected with the TBE virus have been identified in more than 35 countries across Europe and Asia. About TicoVac (TBE vaccine, whole virus inactivated). We routinely post information that may be important to investors on our website at www.Pfizer.com. Pfizer assumes no obligation to update forward?looking

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Drug Target Review

APRIL 17, 2024

Dr Chowell spent a year as a visiting graduate student at the Moe Win Laboratory for Information and Decision Systems at MIT. HLA are the critical molecules that our immune systems use to present peptides to T cells and facilitate recognition and killing in immune responses to pathogens.

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The Pharma Data

DECEMBER 31, 2020

31, 2020 — Blood vessel damage and inflammation in the brains of deceased COVID-19 patients suggest the damage is not caused by the virus, but the body’s immune response to it. The researchers saw no signs of the virus in the tissue samples, which they said may mean that the damage was not caused by the virus itself.

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The Pharma Data

DECEMBER 30, 2020

The young man carries a variant of the virus that is thought to be more contagious — but not more lethal — than variants previously circulating globally this year. In a news release, Colorado health officials reiterated that vaccines already in use should be just as effective against the new variant of the virus.

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Nvidia Developer: Drug Discovery

OCTOBER 5, 2021

A new study out of the Massachusetts Institute of Technology (MIT) could arm healthcare workers with the information needed to effectively treat COVID-19. A new study out of the Massachusetts Institute of Technology (MIT) could arm healthcare workers with the information needed to effectively treat COVID-19 patients.

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The Pharma Data

NOVEMBER 29, 2021

1.1.529 a variant of concern, named Omicron, on the advice of WHO’s Technical Advisory Group on Virus Evolution (TAG-VE). There is currently no information to suggest that symptoms associated with Omicron are different from those from other variants. More information on this will become available in the coming days and weeks.

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