International, Metabolic Stability and Pharmaceuticals

How the AI revolution can accelerate early drug discovery

Drug Target Review

SEPTEMBER 20, 2023

Training AI/ML tools to predict results of otherwise complex and time-consuming calculations is gaining traction in pharmaceutical R&D. To really benefit from AI, the pharmaceutical industry must be more open to data sharing. Research and Development in the Pharmaceutical Industry | Congressional Budget Office [Internet].

Drugs

Drugs Metabolic Stability Computational Chemistry Pharmaceuticals

Obstacles and innovations of macrocyclic drug development

Drug Target Review

JANUARY 16, 2025

Researchers have shown that cell permeability can be improved by designing macrocyclic peptides whose structure includes amide (NH) groups that are engaged in internal hydrogen bonding interactions. Pharmaceuticals , 16(7):996, 2023. Cyclic Peptide Design, Chapter 2: Strategies to Enhance Metabolic Stabilities.

Drug Development

Drug Development Small Molecule Drugs FDA Approval

Drug Discovery Digest

How the AI revolution can accelerate early drug discovery

Obstacles and innovations of macrocyclic drug development

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