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How AI/ML technology has accelerated drug discovery Although AI for drug discovery (AIDD) can be viewed as being in the initial phases of development and acceptance, compounds discovered using AIDD platforms are already entering clinical trials. To really benefit from AI, the pharmaceutical industry must be more open to data sharing.
Phase III trials for MK-0616 commenced in the second half of 2023. Researchers have shown that cell permeability can be improved by designing macrocyclic peptides whose structure includes amide (NH) groups that are engaged in internal hydrogen bonding interactions. Phase 2b randomized trial of the oral PCSK9 inhibitor MK-0616.
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