Mogrify enters research collaboration with the MRC Laboratory of Molecular Biology
Drug Discovery Today
JANUARY 12, 2021
Exploratory research project aims to develop novel protein expression systems via cell reprogramming
Researchers identify potential therapeutic target for early-onset dementia
Drug Discovery World
DECEMBER 8, 2023
The research led by scientists from the Medical Research Council (MRC) Laboratory of Molecular Biology, in Cambridge, UK, could provide a target for the future development of diagnostic tests and treatments. Surprisingly, the protein was not FUS – it was another protein called TAF15.
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smartRNA project joins BII Bio Studio programme
Drug Discovery World
MARCH 21, 2024
The project will be led by Søren Lykke-Andersen, a Senior Scientist at Aarhus University (AU), working at the Department of Molecular Biology and Genetics.
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Tech Theatre ELRIG 2022: First steps towards liquid handling automation
Drug Discovery World
OCTOBER 3, 2022
Product Manager at SPT Labtech, for a fascinating deep dive into the practical considerations of how, when and why you should automate your laboratory’s liquid handling processes. in Chemical Biology. Join Anne Hammerstein, Ph.D., The talk will take place at ELRIG’s Drug Discovery 2022 Tech Theatre, supported by DDW.
Open-source lab robot makes bioautomation accessible for all
Drug Discovery World
JUNE 2, 2023
Opentrons says that while legacy laboratory robotics require extensive software knowledge and months of training, the Flex has an open-source design and accessible application programming interface (API), especially useful for scientists advancing generative AI.
AI provides new insight into preventing human disease
Drug Discovery World
MAY 17, 2023
The study was conducted by researchers at the Universities of Bristol (UK) and Queensland (Australia), and the Medical Research Council Laboratory of Molecular Biology in Cambridge, UK.
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Work begins on life science development at Cambridge Biomedical Campus, UK
Drug Discovery World
JULY 8, 2022
Work has started on the first wholly speculative development of new multi-let laboratory and office space at Cambridge Biomedical Campus in the UK, which is specifically targeting a range of growing biotech and life science businesses. .
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Turning Science into Business: Commercialising CRISPR
Drug Discovery World
OCTOBER 24, 2023
MP : Lithuania is a hub of gene editing, as we not only have the Life Sciences Centre at Vilnius University, but also the European Molecular Biology Laboratory (EMBL). DS: What was the motivation for launching Caszyme and what challenges did you face creating a viable business?
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Nucleic acid therapy accelerator
Drug Target Review
NOVEMBER 23, 2023
About the author Dr William Schafer Group Leader at MRC Laboratory of Molecular Biology William Schafer is a neuroscientist who has investigated conserved principles by which neurons and neural circuits control behaviour.
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Optimizing your ELISA Assays | BMG LABTECH
BMG Labtech
MARCH 11, 2024
Enzyme-Linked Immunosorbent Assays (ELISAs) are an essential technique in today’s laboratory with many applications in the life sciences. 1,2 Anton Schuurs and Bauke van Weemen at the research laboratories of NV Organon, Oss, the Netherlands developed a similar technique which was also published in 1971.
Europe: Where is the drug discovery innovation?
Drug Discovery World
MAY 6, 2024
Cell and gene therapy is a particular area of focus for the region, centred around the VU LSC-EMBL Partnership for Genome Editing Technologies, a partnership between the Vilnius University Life Sciences Center (VU LSC) and the European Molecular Biology Laboratory (EMBL).
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BioNTech to deliver prestigious lecture on mRNA
Drug Discovery World
JULY 26, 2022
The César Milstein Lecture is named in honour of the MRC Laboratory of Molecular Biology (LMB) LMB Nobel Laureate César Milstein. The talk will cover the technology behind the vaccine and the mechanisms of antibody and T cell immune responses triggered by the Covid-19 mRNA vaccine. .
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Women in Stem with Dr Beate Mueller-Tiemann
Drug Target Review
FEBRUARY 19, 2024
I always found science fascinating, but I really fell in love with it in high school when I was introduced to biochemistry and molecular biology. Biochemistry and molecular biology fascinated me in school. Can you tell us about your journey in the field of STEM and the challenges you encountered along the way?
Q&A With Dr. Norbert Makori and Pierre Jolicoeur: The Benefits of Combining Preclinical and Bioanalytical for Your Gene Therapy Studies
Alta Sciences
MARCH 1, 2024
PJ: At Altasciences, we have a range of leading-edge platforms that include ligand binding assays (LBA), NAb, TAb, flow cytometry, and ELISpot, as well as on-site molecular biology instrumentation such as Bio-Rad’s ddPCR system, the NanoDropTM One spectrophotometer, and dedicated polymerase chain reaction (PCR) chambers.
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Repurposing FDA-approved drugs may help combat COVID-19
The Pharma Data
FEBRUARY 25, 2022
. “The SARS-CoV-2 vaccines target the spike protein, but this protein is under strong selection pressure and, as we have seen with Omicron, can undergo significant mutations,” said Joyce Jose, assistant professor of biochemistry and molecular biology, Penn State. 25) in the journal Communications Biology.
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Advancing antibody discovery with AI
Drug Discovery World
NOVEMBER 2, 2023
KS: I have been involved in the field of computational molecular biophysics for many years and more recently in protein design with my work at the European Molecular Biology Laboratory (EMBL). RA: Could you tell me about the launch of AION Labs’ second start-up DenovAI?
Synthesised sea sponge molecule could fight Parkinson’s
Drug Discovery World
JANUARY 26, 2023
Provided by Sophia Kolesnikova of the Laboratory of Marine Natural Compounds Chemistry at the GB Elyakov Pacific Institute of Bioorganic Chemistry. When used in pharmaceuticals, one enantiomer of a molecule may have beneficial therapeutic effects while the other may do nothing at all – or even prove dangerous.
Phages could help to tackle antimicrobial resistance
Drug Target Review
DECEMBER 7, 2023
Phage have been of interest to scientists as tools to understand fundamental molecular biology, as vectors of horizontal gene transfer and drivers of bacterial evolution, as sources of diagnostic and genetic tools, and as novel therapeutic agents. He continued: “CBASS cyclases look a lot like cGAS, so they have to be sensing something.
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What is the largest CRO in the US?
Vial
MARCH 1, 2024
billion in 2023 attributable to its laboratory products and biopharma services segment (53.8% By type of service, clinical research services accounted for the lion’s share of the North American CRO services market, followed by early-phase development services, laboratory services, and consulting services. of total revenue).
Global advances in synthetic biology
Drug Discovery World
NOVEMBER 17, 2022
Lu Rahman selects some recent synthetic biology innovations and the potential they hold to benefit drug discovery. . The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape.
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Trends & Insights: Spotlight Winter Edition
DrugBank
FEBRUARY 9, 2023
Check out previous Trends & Insights Spotlights Academic User Spotlight Subhajit Dutta 1,2 & Ted Natoli 3 Laboratory of Cellular Differentiation & Metabolic Disorder, Department of Biotechnology, National Institute of Technology Durgapur, India. 2 Cancer Program, Broad Institute of MIT and Harvard, USA.
2021 Hansen Family Award goes to Professor Kai Johnsson
The Pharma Data
MARCH 16, 2022
As Professor Patrick Cramer, Professor at the Max-Planck Institute for Multidisciplinary Sciences and Director of the Molecular Biology Department, emphasized in his congratulatory speech: “Kai Johnsson is a world-leading research scientist in chemical biology.
Otto Bayer Award goes to Prof. Ruth Ley PhD
The Pharma Data
FEBRUARY 22, 2021
Born in 1970, the British and American research scientist has been Director of the Department of Microbiome Research at the Max Planck Institute for Developmental Biology in Tübingen since 2016. Before, she was associate professor at Cornell University in the Department of Molecular Biology and Genetics.
Chinese Government Arrests GenScript and Legend Biotech Founder for Smuggling
The Pharma Data
NOVEMBER 23, 2020
Before joining GenScript, Zhu worked at California-based Clontech Laboratories, Inc. as a director of molecular biology. Li Zhu, chief strategy officer at GenScript Biotech, was tapped to fill Zhang’s place on the board. Zhu founded Genetastix Corporation, Inc.,
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AstraZeneca unveils The Discovery Centre (DISC) in Cambridge
The Pharma Data
NOVEMBER 22, 2021
Located within the Cambridge Biomedical Campus1, the physical propinquity of the structure’s m2 laboratories to leading hospitals, the University of Cambridge, other exploration institutions and a number of biotech companies will promote a culture of open cooperation and invention in its inviting open spaces.
Using AI to predict metastatic behaviour of NSCLC
Drug Target Review
APRIL 8, 2024
Dr Govindan is keen on translating genomic discoveries from the laboratory setting to clinical setting to improve the outcomes of patients with lung cancer and mentor trainees and junior faculty members. Chair of the Department of Pathology and Professor of Biochemistry and Molecular Biology. In 2009, he became the Joseph R.
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Merkin Prize in Biomedical Technology awarded to F. William Studier for development of widely used protein- and RNA-production platform
Broad Institute
MAY 14, 2024
William Studier for development of widely used protein- and RNA-production platform The $400,000 award recognizes the far-reaching medical impacts of Studier’s development, in the 1980s, of an efficient and scalable technology to produce mass amounts of RNA and proteins in laboratories that is widely used today all over the world.
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A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic
Broad Institute
APRIL 25, 2024
The project is a collaboration between the Broad and the African Center of Excellence for Genomics of Infectious Diseases (ACEGID) at Redeemer’s University outside Lagos in Nigeria, where Happi is a professor of molecular biology and genomics. Rural clinics use rapid, low-cost tests to detect a few common pathogens.
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Where is the promise for plant-based medicines? Part 1: Cannabis
Drug Discovery World
AUGUST 3, 2023
Susan Audino is ISO Assessor and Instructor, Scientific Advisor at AOAC International CASP, and Chemistry Laboratory Consultant at SA Audino & Associates, LLC. 12 Cristina Sanchez, Associate Professor of Biochemistry and Molecular Biology, School of Biology, Complutense University, was featured as a Plant Science Pioneer.
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Study offers insights on why the elderly are more susceptible to COVID-19
The Pharma Data
NOVEMBER 9, 2021
Elias is part of a National Institutes of Health-funded laboratory that focuses on the cell and molecular biology of lung injury and repair.
Sosei Heptares’ COVID-19 Program Identifies Potent Broad Spectrum Anti-Viral Small Molecules for Further Development
The Pharma Data
NOVEMBER 19, 2020
The program is being led by Sosei Heptares and progressed in collaboration with multiple companies including Syngene International, Domainex, Fidelta, o2h Discovery, Piramal, WuXi AppTec and the MRC Laboratory of Molecular Biology.
Roche launches new quantitative antibody test to measure SARS-CoV-2 antibodies, to support the evaluation of vaccines
The Pharma Data
SEPTEMBER 17, 2020
The test is the latest addition to the comprehensive Roche diagnostic portfolio to help healthcare systems combat COVID-19 through testing in the laboratory and at the point of care. Hospitals and reference laboratories can run the test on Roche’s cobas e analyzers which are widely available around the world. Academic Press.
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Forty of the Nation’s Most Talented Young Scientists Named Finalists in Regeneron Science Talent Search 2021
The Pharma Data
JANUARY 21, 2021
Founded and led for 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to eight FDA-approved treatments and numerous product candidates in development, all of which were homegrown in our laboratories.
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Meet the researcher: Richard Bouffard
Drug Discovery World
NOVEMBER 7, 2023
RB: There have been many high points, but my biggest career highlight, so far, would be being able to walk into a mostly empty room and build a histopathology laboratory from the ground up. I believe I was the best student when I was studying molecular biology —and Italian —simultaneously. Balance is key.
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Empowering scientists in the genomic revolution
sptlabtech
JUNE 9, 2023
However, with so many individual processes involved in NGS library preparation, you might think that automating this workflow requires several instruments costing large amounts of laboratory space. Enter firefly ®. What benefits can you expect to see from making the switch to automated liquid handling with firefly?
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Liquid Handling - Empowering scientists in the genomic revolution
sptlabtech
JUNE 9, 2023
However, with so many individual processes involved in NGS library preparation, you might think that automating this workflow requires several instruments costing large amounts of laboratory space.
Breaking the Speed Limit on Cell Division
Codon
JUNE 25, 2024
So-called primary cells, harvested from living tissues and cultured in the laboratory, can take weeks to grow and spread across a culture flask, hampered partly by their large genomes, which take time to copy. As novel speed adaptations accumulate in laboratory cultures, researchers can cherry-pick bacteria that divide faster.
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The Promise of Gas Vesicles
Codon
JUNE 18, 2024
These algae are “one of the most interesting, at least one of the most striking, of the plankton,” wrote Klebahn, who transported the cells back to his laboratory in Hamburg, one hundred kilometers to the south. Light and Sound Progress in biology has long been driven by light. ” During his Ph.D., up to 17 MHz.
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The use-case for NGS
Drug Discovery World
OCTOBER 25, 2023
I started my career in a molecular genetics diagnostics laboratory in the NHS and I remember NGS just starting to be evaluated for routine use for every sample that came into the lab, rather than us having to examine single mutations in single genes. However, NGS will have impact in any genetic-based diseases.
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Alpaca nanobodies potently neutralize SARS-CoV-2 variants
The Pharma Data
MARCH 25, 2022
“With the help of advanced laboratory techniques, we were able to identify a panel of nanobodies that very effectively neutralized several variants of SARS-CoV-2,” says Gerald McInerney, professor at the Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, and joint senior author of both studies.
The history – and the future – of antibody discovery technologies
DrugBaron
FEBRUARY 16, 2021
The first technological leap was the invention of hybridoma technology, by César Milstein together with his post-doc Georges Köhler working at the world-famous Laboratory of Molecular Biology in Cambridge.
Synthetic Origins
Codon
APRIL 2, 2024
But in those early years, everything in the laboratory was so slow and difficult. I was reading a lot of molecular biology papers about different systems, especially circadian clocks, and also a book called Biological Feedback , by Thomas and D’Ari, that sketched out really simple models for different kinds of feedback circuits.
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Code breaking and the Human Genome Project
The Open Targets Blog
APRIL 25, 2023
Although the estate was undoubtedly pretty, the Hall had seen better days and was rather dominated by a 1950s building that provided laboratories for the light engineering company that had owned the site. For the genome sequencing at the Sanger Centre, we also brought together diverse people to achieve our goals.
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The inner workings of antibiotics
Drug Discovery World
OCTOBER 11, 2023
About the author: Dr Luke Clifton, PhD in Biophysical Chemistry, works as an Instrument Scientist in the neutron reflectometry group at the ISIS Neutron and Muon Source at Rutherford Appleton Laboratory in the UK. Dr Clifton has developed novel bio-membrane sample systems which have been used to answer applied questions of membrane biology.
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