Remove Laboratories Remove Molecular Biology Remove Small Molecule Remove Virus
article thumbnail

Sosei Heptares’ COVID-19 Program Identifies Potent Broad Spectrum Anti-Viral Small Molecules for Further Development

The Pharma Data

The Company is also aiming to leverage the highly conserved structure of the SARS-CoV-2 M pro protease as a basis for the design of novel oral small molecules against predicted future variants of SARS-CoV-2 and other related human viruses.

article thumbnail

Phages could help to tackle antimicrobial resistance

Drug Target Review

Phage have been of interest to scientists as tools to understand fundamental molecular biology, as vectors of horizontal gene transfer and drivers of bacterial evolution, as sources of diagnostic and genetic tools, and as novel therapeutic agents. He continued: “CBASS cyclases look a lot like cGAS, so they have to be sensing something.

RNA 59
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Study offers insights on why the elderly are more susceptible to COVID-19

The Pharma Data

.” The findings not only answer important questions about key mechanisms of the complex SARS-CoV-2 virus, Elias said, but also have direct implications for the development of therapeutics to control the viral infection. “This means there will be less infection in the presence of this therapeutic FRG antibody.”

article thumbnail

Global advances in synthetic biology

Drug Discovery World

Lu Rahman selects some recent synthetic biology innovations and the potential they hold to benefit drug discovery. . The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape.

article thumbnail

Synthetic biology tools advancing and accelerating drug discovery efforts

Drug Discovery World

Although simple in its concept, the method itself is highly involved and requires the use of hazardous, unstable chemicals, making the whole ordeal labour-intensive and cost-prohibitive for individual laboratories to synthesise DNA sequences on their own. Engineering biosensors for specific functions .

DNA 246
article thumbnail

The role of anti-viral drug development in a new pandemic era

Drug Target Review

Since the 20 th century, all known viral pandemics, including HIV, influenza, SARS CoV-1, SARS, CoV-1, and mpox, have resulted from a virus ‘spilling over’ from animals into humans. For example, scientists cannot accurately predict which town or village will have the next Nipah virus outbreak.