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The Power of AI in Drug Discovery and Development

The Connected Lab

It is reported that every one of the major pharmaceutical companies has announced a partnership with at least one AI-based drug development company, but how is AI being used to facilitate drug development? Thermo Fisher Scientific is at the forefront for enabling centralized data management for laboratories. Nature , vol.

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Best CDMO Practices for Startups: Navigating the Complex World of Contract Development and Manufacturing

Drug Patent Watch

The pharmaceutical landscape is evolving rapidly, with small and medium-sized biotech companies increasingly taking center stage in innovation. In 2017, small and medium-sized biotech companies accounted for 51% of FDA market approvals, while large pharma companies were the originators in only 28% of approvals[4].

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Drug Repurposing: A New Life for Old Drugs

DrugBank

Currently, about one-third of recent drug approvals and 25% of the pharmaceutical industry's annual revenue is coming from repurposed drugs.This trend is being championed industry-wide, by public organizations and nonprofits, with numerous small companies diving in and academic publications on the subject showing great popularity.

Drugs 71
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Women in Stem with Dr Mrunal Jaywant

Drug Target Review

I worked on a project that required development of a highly sensitive method and analysis of an active pharmaceutical ingredient to determine accurate levels of two potential genotoxic impurities. We are responsible for formulating a long-term strategy for addressing nitrosamine impurities in pharmaceuticals.

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What is the largest CRO in the US?

Vial

Introduction Contract research organizations (CROs) are essential in pharmaceutical research and development (R&D). billion in 2023 attributable to its laboratory products and biopharma services segment (53.8% US), Laboratory Corporation of America Holdings (Labcorp) (US), ICON Plc (Ireland), and WuXi AppTec (China).

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Case study: Extracting tidy data from Open Targets Genetics with Otargen

The Open Targets Blog

Amir Feizi is the Director of Bioinformatics at OMass Therapeutics, a spinout from Professor Dame Carol Robinson’s Laboratory at the University of Oxford. Although pharma companies can be competitive, this kind of tool will not generate any IP, and it saved us so much work that we knew it could be of real benefit to the community.

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Predictive Oncology looks to improve precision cancer Rx development with AI-driven platform

Predictive Oncology

Because pharma companies can’t predict which early-stage drug candidates will succeed, they end up playing a “numbers game,” according to Bush, by advancing multiple compounds. What happens if we are able to provide information to the pharmaceutical company that doubles that [and] one in 10 molecules actually make it?”