Broad Institute

JUNE 18, 2024

Simple test for flu could improve diagnosis and surveillance By Allessandra DiCorato June 18, 2024 Breadcrumb Home Simple test for flu could improve diagnosis and surveillance A low-cost CRISPR-based paper strip test distinguishes between influenza types and can be reprogrammed to recognize different viruses including the H5N1 bird flu virus.

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Agency IQ

DECEMBER 11, 2023

Reference Laboratories for class D IVDs This week, the Commission announced the designation of the first group of E.U. Reference Laboratories with publication of the implementing regulation in the Official Journal. Reference Laboratories (EURLs) against specific requirements known as “common specifications” (CS).

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Science Daily: Pharmacology News

NOVEMBER 9, 2023

Using an accelerated arms race between bacteria and viruses, researchers are documenting rapid evolutionary processes in simple laboratory flasks in only three weeks. Rather than a slow, gradual process as Darwin envisioned, biologists can now see how evolutionary changes unfold on much more accelerated timescales.

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Drug Discovery World

OCTOBER 28, 2022

A panel of investigational monoclonal antibodies (mAbs) targeting different sites of the Epstein-Barr virus (EBV) have been shown to block infection when tested in human cells in a laboratory setting. . There is no licensed vaccine to protect against the virus. . EBV is one of the most common human viruses.

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Drug Discovery World

MAY 24, 2024

Atara Biotherapeutics has submitted a Biologics License Application (BLA) for Tabelecleucel (Tab-cel), a for treatment of Epstein-Barr virus positive post-transplant lymphoproliferative disease (EBV+ PTLD) with the US Food and Drug Administration (FDA). There are currently no FDA approved therapies in this treatment setting.

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The Pharma Data

JANUARY 11, 2021

Our proprietary Laboratory Developed Test has the ability to dramatically increase testing capacity and help get ahead of the curve with this devastating virus.”. To book a test, members of the public can visit www.cardiai.com. Those with commercial requirements can contact +1 (800) 403-8122.

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Drug Discovery World

JUNE 6, 2024

Moderna recently secured FDA approval for the first mRNA vaccine to treat something other than Covid-19 – it’s respiratory syncytial virus (RSV) vaccine mRESVIA (mRNA-1345).

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Drug Discovery World

OCTOBER 28, 2022

Over the last seven days we’ve seen discoveries that could lead to new treatments for Covid-19, pancreatic cancer and Epstein-Barr virus, as well as the launch of the UK’s largest health research programme and the innovative application of a Nobel prize-winning chemistry technique. . This week’s top stories: .

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Drug Discovery World

AUGUST 17, 2023

The researchers showed that when mice were infected with the flu virus, blood was found in the airspaces in the lungs, as it had leaked across the damaged barrier. Natural molecules in cruciferous vegetables are dietary ‘ligands’ for AHR , which means they activate AHR to target a number of genes.

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Drug Discovery World

OCTOBER 21, 2022

A research team from Boston University has caused controversy for work involving the creation of a hybrid SARS-CoV-2 virus. . The idea behind the study was to investigate the role of the Omicron spike and assess whether mutations in the Omicron spike protein made the virus more transmissible. .

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The Pharma Data

APRIL 1, 2021

The Elecsys® EBV panel consists of three immunoassays: Elecsys EBV IgM, Elecsys EBV VCA IgG, and Elecsys EBV EBNA IgG, that detect antibodies specific to the Epstein-Barr virus (EBV), at different stages of infection. About Epstein-Barr Virus (EBV) Testing. 1-2 It is mainly transmitted by saliva, or via organ or cell transplants.

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The Pharma Data

AUGUST 3, 2021

The drug, which has undergone several clinical trials for human conditions but has not yet received approval to treat humans, inhibited the replication of SARS-CoV-2, the virus that causes COVID-19, in human cell cultures and in a mouse model, leading to much lower viral loads. The research team, including scientists from the U.S.

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Drug Discovery World

JULY 28, 2022

Researchers at the Francis Crick Institute in the UK, have shown that a specific area of the SARS-CoV-2 spike protein is a promising target for a pan-coronavirus vaccine that could offer some protection against new virus variants, common colds, and help prepare for future pandemics.

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Drug Discovery World

FEBRUARY 20, 2024

Currently, only a handful of adjuvants are available for human use in licensed vaccines. SaponiQx’s STIMULON QS-21is an adjuvant component in vaccines for shingles, malaria, and respiratory syncytial virus.

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The Pharma Data

JUNE 26, 2021

Early in the COVID-19 pandemic, scientists identified how SARS-CoV-2, the virus that causes COVID-19, gets inside cells to cause infection. However, the discovery does show that the virus can change in unexpected ways and find new ways to cause infection. Now, researchers at Washington University School of Medicine in St.

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PerkinElmer

APRIL 21, 2020

Although the novel coronavirus is the subject of nearly every media story right now, several years ago it was the Zika virus (ZIKV) gathering a great deal of attention. Here, we describe the novel use of high content imaging solutions (HCS) in a study to identify possible Zika virus inhibitors that could be translated into therapeutic form.

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Drug Discovery World

MARCH 25, 2024

The Jackson Laboratory and LG AI Research The Jackson Laboratory (JAX) and LG AI Research have created an alliance between JAX’s knowledge of biomedical research and data analysis and LG’s AI research and product development understanding.

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Drug Discovery World

SEPTEMBER 22, 2022

Dr Quinton Fivelman PhD, Chief Scientific Officer at London Medical Laboratory, says: “Finally, there may be a silver lining to the pandemic cloud. It seems a response from the body caused by fighting the Omicron variant also stops the influenza virus from replicating.

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Drug Discovery World

AUGUST 7, 2023

The centre is situated at the UK Health Security Agency (UKHSA) Porton Down site, where it is co-located with other services delivered separately by partners including the Defence Science and Technology Laboratory.

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PLOS: DNA Science

MAY 16, 2024

That’s thanks to accelerated genome sequencing technologies, expanded laboratory capabilities, and interacting infrastructure on a global level. A Novel Virus Appears In retrospect, everything unfolded with astonishing speed. We’re still figuring out exactly how the virus travels from air to human respiratory tract.

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Drug Discovery World

DECEMBER 18, 2023

The researchers drew comparisons between the immune system activity of past HIV vaccine study participants and people with HIV who naturally keep the virus from replicating even in the absence of antiretroviral therapy (ART), called ‘long-term non-progressors’ or ‘elite controllers’ (LTNPs/ECs).

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Drug Discovery World

NOVEMBER 30, 2022

We have been able to validate the Clamp2 platform in the laboratory and show that it is equivalent to the original platform across multiple virus families including influenza virus, Nipah virus and SARS-CoV-2,” Dr Chappell said.

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Drug Discovery World

DECEMBER 6, 2023

Obulytix’s cutting-edge, AI-assisted approach exemplifies the pioneering science that seamlessly aligns with our vision of advancing robust scientific principles from the laboratory to the patient’s bedside.” Current estimates suggest that antibiotic-resistant bacteria could claim 10 million lives per year by 2050.

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Drug Discovery World

MAY 29, 2023

The US Food and Drug Administration has approved Krystal Biotech’s Vyjuvek, a herpes-simplex virus type 1 (HSV-1) vector-based gene therapy, for the treatment of dystrophic epidermolysis bullosa (DEB).

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Drug Discovery World

OCTOBER 20, 2023

GenomeFrontier partners with BioCina on CAR-T therapy CDMO BioCina and GenomeFrontier Therapeutics will partner on the development of virus-free CAR-T products for cancer treatment. BioCina will provide process development and GMP manufacturing for Minicircle DNA and Plasmid DNA.

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The Pharma Data

SEPTEMBER 7, 2020

Immunocompromised transplant patients are at risk of major complications when infected with BK virus. cobas BKV test addresses critical need for hospitals and laboratories to have standardised and comparable results across institutions. Basel, 8 September 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced U.S.

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Drug Target Review

APRIL 17, 2024

Dr Chowell spent a year as a visiting graduate student at the Moe Win Laboratory for Information and Decision Systems at MIT. During residency, he conducted laboratory research with Dr Timothy Chan investigating predictors of response to immunotherapy as part of the American Board of Radiology Holman Research pathway.

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BMG Labtech

MARCH 11, 2024

Enzyme-Linked Immunosorbent Assays (ELISAs) are an essential technique in today’s laboratory with many applications in the life sciences. 1,2 Anton Schuurs and Bauke van Weemen at the research laboratories of NV Organon, Oss, the Netherlands developed a similar technique which was also published in 1971.

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Drug Discovery World

MARCH 14, 2023

The great advantage of these vaccines, in addition to their effectiveness, is the ability to develop them very quickly: once the genetic sequence of the virus SARS-CoV2 (Covid-19) was published, it took only 63 days to begin the first clinical trial.

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The Pharma Data

AUGUST 4, 2020

Accurate monitoring of Epstein-Barr virus DNA levels is critical, as they are associated with a range of life threatening-diseases including cancer in transplant patients. Test meets World Health Organization standards for consistent result reporting among laboratories across the U.S.,

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Broad Institute

APRIL 25, 2024

Hospitals with laboratories use pathogen detection technology developed by Sabeti’s group that scans samples for a panel of additional pathogens. It can take only 36 hours for a virus that is emerging in a very remote place to find itself in New York or Paris — they are just a few flights away,” Happi said.

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The Pharma Data

JANUARY 6, 2021

A Novel Ebola Virus VP40 Matrix Protein-Based Screening for Identification of Novel Candidate Medical Countermeasures.’ sangivamycin) has broad-spectrum antiviral activity in laboratory-based assays against several viruses. ROCHESTER, N.Y. , 7, 2021 /PRNewswire/ — OyaGen, Inc. Bennett et al., About OYA1. OYA1 (a.k.a.

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Broad Institute

MAY 14, 2024

William Studier for development of widely used protein- and RNA-production platform The $400,000 award recognizes the far-reaching medical impacts of Studier’s development, in the 1980s, of an efficient and scalable technology to produce mass amounts of RNA and proteins in laboratories that is widely used today all over the world.

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Drug Discovery World

NOVEMBER 1, 2022

Together with Alexei Bygrave, Assistant Professor at Tufts University, Blackshaw and Ling made packages of alternative spliced messenger RNA that could be delivered into cells via a benign virus. In human ocular melanomas cultured in the laboratory, the scientists delivered SLED packages into only melanoma cells that lack the SF3B1 gene.

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Drug Discovery World

AUGUST 1, 2022

Chief of the Virus Persistence and Dynamics Section in the VRC Laboratory of Immunology, described NIAID’s long-standing collaboration with a bioengineering research group at the University of California, San Francisco. In the presentation, Eli Boritz, M.D.,

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Drug Discovery World

MAY 17, 2023

The study was conducted by researchers at the Universities of Bristol (UK) and Queensland (Australia), and the Medical Research Council Laboratory of Molecular Biology in Cambridge, UK. Viruses such as SARS-CoV-2 and HPV need the Commander complex to infect cells.

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Drug Target Review

FEBRUARY 15, 2024

Since the 20 th century, all known viral pandemics, including HIV, influenza, SARS CoV-1, SARS, CoV-1, and mpox, have resulted from a virus ‘spilling over’ from animals into humans. For example, scientists cannot accurately predict which town or village will have the next Nipah virus outbreak.

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