Drug Target Review

FEBRUARY 26, 2024

Our data demonstrate that the CoREST complex is a critical mediator of the distinct melanoma phenotypes, working through the regulation of both the phenotype-defining genes MITF and AXL as well as the master regulators of epithelial-to-mesenchymal transitions (EMT) and phenotype switching in melanoma and other cancers, SNAIL/SLUG/ZEB1/ZEB2.

Therapies 59

Therapies Molecular Biology Regulations Medical Schools 59

Drug Discovery World

MAY 6, 2024

Mazzetti and Schneider give the example of T3 Pharmaceuticals, a University of Basel spin-off that developed a proprietary cancer therapy platform based on regulating and harnessing the natural behaviours of live bacteria. So, in this way there is a cross fertilisation from the bigger companies to newer ones.

Drugs 147

Drugs Science Molecular Biology Clinical Trials 147

Codon

JULY 17, 2024

The word “amateur” can carry a negative connotation , but as Forrest Mims wrote in Science magazine in 1999, the word “retains the meaning of its French root amour , love, for amateurs do science because it’s what they love to do.” I mean, how did people do molecular biology fifty or one hundred years ago?

Laboratories 86

Laboratories Engineering Molecular Biology Science 86

Codon

FEBRUARY 13, 2024

doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of untreatable, drug-resistant infections.

Therapies 118

Therapies Virus DNA Clinical Trials 118

Codon

JUNE 26, 2023

This essay , in Asterisk Magazine , is the best I’ve seen at explaining why cultivated meat is so expensive in the first place. Future Nobel Laureate, Paul Berg, narrated the video, which quickly became a cult classic moment in molecular biology history. plasmidsaurus @arjunrajlab (Regulation in biology is incredible.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

JUNE 26, 2023

This essay , in Asterisk Magazine , is the best I’ve seen at explaining why cultivated meat is so expensive in the first place. Future Nobel Laureate, Paul Berg, narrated the video, which quickly became a cult classic moment in molecular biology history. plasmidsaurus @arjunrajlab (Regulation in biology is incredible.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

AUGUST 10, 2023

Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Journal of Molecular Biology (1961). Gene Expression and Regulation. Nature Reviews Molecular Cell Biology (2008). Link Molecular Cloning Techniques , by AddGene. & Xie X.S.

DNA 91

DNA Cell Biology Molecular Biology Engineering 91