Drug Discovery World
MARCH 13, 2024
Another successful NUS spin-out is RNA company Ephyra, now based in Cambridge, England, which is developing a new class of therapeutics known as designer sponge RNAs. Now we are still in collaboration to set up better infrastructure like a genome centre and translational laboratory in the health system.”
Codon
MAY 30, 2023
The researchers first compared the editing efficiency of different versions of IscB when coupled with 'ωRNA,' which guides the enzyme to the right spot on the DNA. A particular variant, named IscB*-ωRNA*, had the highest editing efficiency across multiple different sites in the genome. Read more in Nature Methods.
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Codon
MAY 30, 2023
The researchers first compared the editing efficiency of different versions of IscB when coupled with 'ωRNA,' which guides the enzyme to the right spot on the DNA. A particular variant, named IscB*-ωRNA*, had the highest editing efficiency across multiple different sites in the genome. Read more in Nature Methods.
Codon
AUGUST 10, 2023
Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Link CRISPR-Cas →CRISPR-Cas: biology, mechanisms and relevance , by Hille F. & & Charpentier E. Philosophical Transactions of the Royal Society B (2016).
Codon
MARCH 26, 2023
Link Experimental Tests of the Virtual Circular Genome Model for Nonenzymatic RNA Replication. Link U1 snRNP increases RNA Pol II elongation rate to enable synthesis of long genes. Link Gene Editing, CRISPR & Genetic Control *Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases.
The Pharma Data
OCTOBER 19, 2021
With this expanded blessing, clinicians can add Biktarvy to their magazine of options to help insure these children maintain virologic repression with a treatment option that makes sense for them.” HIV-1 RNA wasn’t collected at Week 24 for two actors because of COVID-19 epidemic-affiliated study dislocation.
Codon
AUGUST 10, 2023
Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Link In vitro integration of ribosomal RNA synthesis, ribosome assembly, and translation , by Jewett M.C. Link CRISPR-Cas →CRISPR-Cas: biology, mechanisms and relevance , by Hille F. & & Charpentier E.
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