Drug Discovery World

MARCH 13, 2024

Another successful NUS spin-out is RNA company Ephyra, now based in Cambridge, England, which is developing a new class of therapeutics known as designer sponge RNAs. Now we are still in collaboration to set up better infrastructure like a genome centre and translational laboratory in the health system.”

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Government Science Pharmaceuticals Vaccine 173

Codon

MAY 30, 2023

The researchers first compared the editing efficiency of different versions of IscB when coupled with 'ωRNA,' which guides the enzyme to the right spot on the DNA. A particular variant, named IscB*-ωRNA*, had the highest editing efficiency across multiple different sites in the genome. Read more in Nature Methods.

DNA 52

DNA RNA Engineering Vaccine 52

Codon

MAY 30, 2023

The researchers first compared the editing efficiency of different versions of IscB when coupled with 'ωRNA,' which guides the enzyme to the right spot on the DNA. A particular variant, named IscB*-ωRNA*, had the highest editing efficiency across multiple different sites in the genome. Read more in Nature Methods.

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DNA RNA Engineering Vaccine 52

Codon

MARCH 24, 2024

Water accounts for 70 percent of a bacterium by mass; the other 30 percent includes everything else: proteins, RNA, DNA, lipids, and so on. If the technology proved successful in human beings, it would take Moderna weeks, not years, to make a new product,” wrote Catherine Elton in Boston Magazine.

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Engineering Vaccine Production RNA 87

Codon

MARCH 12, 2023

The central dogma is often depicted as DNA→RNA→protein, but it’s much more: A biophysical marvel inside the smallest of vessels. Asterisk Magazine 13 of 31. Eterna is an online game (there’s also an app) where anyone on the internet can solve puzzles by manipulating RNA sequences and simulating the results.

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DNA Engineering RNA Therapies 52

The Pharma Data

OCTOBER 19, 2021

With this expanded blessing, clinicians can add Biktarvy to their magazine of options to help insure these children maintain virologic repression with a treatment option that makes sense for them.” HIV-1 RNA wasn’t collected at Week 24 for two actors because of COVID-19 epidemic-affiliated study dislocation.

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Treatment FDA Approval RNA Drugs 40

Codon

MARCH 26, 2023

Link Experimental Tests of the Virtual Circular Genome Model for Nonenzymatic RNA Replication. Link U1 snRNP increases RNA Pol II elongation rate to enable synthesis of long genes. Link Gene Editing, CRISPR & Genetic Control *Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases.

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DNA Engineering RNA Small Molecule 52