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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

The researchers first compared the editing efficiency of different versions of IscB when coupled with 'ωRNA,' which guides the enzyme to the right spot on the DNA. A particular variant, named IscB*-ωRNA*, had the highest editing efficiency across multiple different sites in the genome. Read more in Nature Methods.

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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

The researchers first compared the editing efficiency of different versions of IscB when coupled with 'ωRNA,' which guides the enzyme to the right spot on the DNA. A particular variant, named IscB*-ωRNA*, had the highest editing efficiency across multiple different sites in the genome. Read more in Nature Methods.

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Codon: Notes on Progress #2

Codon

The central dogma is often depicted as DNA→RNA→protein, but it’s much more: A biophysical marvel inside the smallest of vessels. Base editor proteins were delivered into the mice using a virus, called AAV9. coli genes into a piece of simian virus DNA. Asterisk Magazine 13 of 31. Biology is a Burrito.

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Codon Digest: Moore's Law

Codon

Link Experimental Tests of the Virtual Circular Genome Model for Nonenzymatic RNA Replication. Link U1 snRNP increases RNA Pol II elongation rate to enable synthesis of long genes. Link A DNA tumor virus globally reprograms host 3D genome architecture to achieve immortal growth. Link Probing metabolism in an E. Mimoso C.A.

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Codon Digest: Hackathon Prize Winners

Codon

A phage is a virus that infects bacteria. A T4 phage can hold 171,000 bases of DNA or other molecules, including proteins and RNA. It uses single-molecule RNA fluorescence to measure mRNAs and fluorescent reporters to measure the proteins. ” Bacteriophages infect a bacterium. They’re incredibly versatile. in Nature.

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Codon Digest: Hackathon Prize Winners

Codon

A phage is a virus that infects bacteria. A T4 phage can hold 171,000 bases of DNA or other molecules, including proteins and RNA. It uses single-molecule RNA fluorescence to measure mRNAs and fluorescent reporters to measure the proteins. ” Bacteriophages infect a bacterium. They’re incredibly versatile. in Nature.

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Codon Digest: Ghana Approves A Better Malaria Vaccine

Codon

Most people would take the two CRISPR gene-editing components (a Cas9 protein and guide RNA), package them up inside of a virus, and then inject the viruses into the skulls of mice. ” Quanta Magazine. If you want to edit a gene inside of a neuron, what do you do? These fat bubbles are injected straight through the skull.

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