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A mirrored organism would use right-handed molecules everywhere a naturally-occurring organism uses left-handed ones, and vice versa. Some scientists even think it had a virus defense system; “researchers say LUCA likely housed 19 CRISPR genes, which bacteria use to slice up viral threats,” reports Quanta Magazine.
Compact gene editors , called enOsCas12f1 and enRhCas12f1, are smaller than many existing Cas proteins and can thus be more easily delivered in a single virus for gene therapies. Read An RNA-based system to study hepatitis B virus replication and evaluate antivirals. ” Joshua Sokol for Quanta Magazine. Science Advances.
Read *An engineered influenza virus to deliver antigens for lung cancer vaccination. Read Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies. Read Programming inactive RNA-binding smallmolecules into bioactive degraders. My essay for Works in Progress magazine.
Read *An engineered influenza virus to deliver antigens for lung cancer vaccination. Read Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies. Read Programming inactive RNA-binding smallmolecules into bioactive degraders. My essay for Works in Progress magazine.
Link A DNA tumor virus globally reprograms host 3D genome architecture to achieve immortal growth. Link *Design of Four Small-Molecule-Inducible Systems in the Yeast Chromosome, Applied to Optimize Terpene Biosynthesis. Link A generalizable nanopore sensor for highly specific protein detection at single-molecule precision.
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