Drug Discovery World

DECEMBER 19, 2023

We’re excited to support Immusoft’s program, as our goal is to always move the most promising research forward as fast as we can,” said Dr Abla Creasey, Vice President of Therapeutics Development, California Institute of Regenerative Medicine (CIRM).

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Drug Discovery World

MARCH 7, 2024

Research published in Cell Genomics has shown that prostate cancer includes two different subtypes of the disease, also known as evotypes. The researchers analysed the DNA of prostate cancer samples in 159 patients using whole genome sequencing and used an AI technique known as neural networks to compare the different samples.

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Disease Medical Schools DNA International 148

Drug Discovery World

OCTOBER 13, 2023

Researchers at Harvard Medical School (HMS) in the US and the University of Oxford have developed a new artificial intelligence (AI) tool named EVEscape that can predict new viral variants before they emerge. million funding from UK Research and Innovation (UKRI).

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Drug Discovery World

DECEMBER 6, 2023

The researchers have discovered a novel population of stem cells – marked by the Gremlin 1 gene – responsible for the progression of osteoarthritis. A Phase III trial of Sprifermin trial is ongoing, and researchers envision public access to this treatment soon.

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Medical Schools Clinical Trials Pharmaceuticals Trials 265

Broad Institute

JANUARY 25, 2024

We’ve come to realize recently that there is a lot more information that we can get from our retina images than we thought was possible,” says senior author Nazlee Zebardast, director of glaucoma imaging at Mass Eye and Ear and an assistant professor of ophthalmology at Harvard Medical School.

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Disease Research Medical Schools Science 124

Drug Discovery World

JANUARY 26, 2023

DDW Editor Reece Armstrong explores recent research looking into why cancer cells are so effective at avoiding the body’s immune system. Scientists may have discovered clues to why cancer cells can avoid the body’s immune system in a study conducted by researchers at Harvard Medical School.

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Medical Schools Cell Biology Research Therapies 130

Broad Institute

OCTOBER 23, 2023

Researchers still do not fully understand why, in part because people of South Asian descent are largely underrepresented in genomic and cardiometabolic research. Researchers still do not fully understand why, in part because people of South Asian descent are largely underrepresented in genomic and cardiometabolic research.

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Drug Discovery World

JUNE 12, 2024

The research project will also explore proteomic pathways associated with treatment response and immune-related adverse events (irAEs), offering potential insights into treatment options and biological patterns of resistance.

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Drug Discovery World

JULY 29, 2022

Isselbacher Professor of Medicine in the Field of Gastroenterology at Harvard Medical School and Massachusetts General Hospital, a core institute member at the Broad Institute of MIT and Harvard, and co-director of the Center for Microbiome Informatics and Therapeutics at MIT. Study after study had suggested that A.

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Research Immune Response Medical Schools Disease 130

Broad Institute

DECEMBER 20, 2023

In a study appearing in Nature , the researchers showed that these compounds could kill methicillin-resistant Staphylococcus aureus (MRSA) grown in a lab dish and in two mouse models of MRSA infection. This knowledge could help researchers to design additional drugs that might work even better than the ones identified by the model. “Our

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Drug Discovery World

SEPTEMBER 3, 2024

In this new substudy of the SELECT Trial, researchers looked at whether once-weekly semaglutide (2.4mg) reduced rates of all-cause death, CV death, and non-CV death, including death from Covid-19. However, it has also been associated with an increase in suicidal thoughts.

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Medical Schools Trials Disease Hospitals 148

Drug Discovery World

APRIL 1, 2024

An analysis of how brains with different forms of autism develop has revealed common underlying mechanisms that may respond to existing medications.

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Medical Schools Cell Biology Regulations Research 148

Drug Discovery World

FEBRUARY 6, 2024

Catherine Brownstein is an Assistant Professor in Pediatrics at Harvard Medical School and the Assistant Director of the Molecular Genetics Core Facility at Boston Children’s Hospital. Researchers gain insights into the latest trends, methodologies, and discoveries shaping the field.

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Drug Discovery World

AUGUST 25, 2023

Paul Schulz, the Rick McCord Professor in Neurology with McGovern Medical School at UTHealth Houston, was senior author of the study. Enhancing the efficiency of immune cells “We hypothesise that the reduced risk of AD associated with vaccines is likely due to a combination of mechanisms,” another researcher Avram Bukhbinder said.

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Vaccine Medical Schools Immune Response Disease 130

Broad Institute

MARCH 8, 2024

Little is known about what pathogens cause these infections, and so these “non-malarial febrile illnesses” (NMFI) often fly under the radar of infectious disease surveillance programs because researchers don’t know which pathogens to look for. Siddle : The team in Senegal has phenomenal expertise both in the clinic and in the lab.

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Drug Discovery World

NOVEMBER 28, 2023

The peer-reviewed article titled ‘Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson’s disease (PD) mouse model’ was the result of collaborative work between Cambridge University, Harvard Medical School, and Mission Therapeutics.

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Drug Discovery World

JULY 5, 2024

” “IgG4-RD is a devastating, chronic, immune-mediated disease that has just begun to be fully understood over the last few decades,” said John Stone, Principal Investigator, and a Professor of Medicine at Harvard Medical School and the Edward A Fox Chair in Medicine at the Massachusetts General Hospital.

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Drug Discovery World

JULY 21, 2022

Two doses of Covid-19 vaccines were sufficient in providing protection against severe cases of the infectious disease, according to new research. . The researchers used NHS health records from over 7 million adults to assess vaccine effectiveness. Bristol Medical School: Population Health Sciences (PHS)?and

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Drug Discovery World

MAY 4, 2023

New research in mice has identified how gut bacteria alter the body’s response to PD-1 checkpoint blockade immunotherapy, currently used for the treatment of 25 forms of cancer. Their research showed that when PD-L1 or PD-L2 interact with another molecule, PD-1, on the surface of T cells, the activity of T cells is kept in check.

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Medical Schools Small Molecule Research Treatment 130

Drug Discovery World

OCTOBER 13, 2023

Millions have been affected by this terrible condition which makes research like this critically important as we seek to find new ways to improve care.” The first phase of research will begin in January 2024 and will look at a series of measures, including exercise tolerability.

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Medical Schools Hospitals Virus Treatment 148

Drug Discovery World

NOVEMBER 8, 2023

While traditional approaches to clinical trials have helped us manage some of these conditions to a certain extent, they alone may not provide us the velocity we need to accelerate the research and conquer these diseases, raising the possibility that technologies such as artificial intelligence (AI) may hold the answer.

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Clinical Trials Trials Disease Medical Schools 183

Drug Discovery World

JANUARY 5, 2023

CANbridge Pharmaceuticals has exercised its option to secure the exclusive global rights to develop, manufacture and commercialise a novel gene therapy to treat spinal muscular atrophy (SMA) from UMass Chan Medical School. . It also exhibited much less liver toxicity when administered intravenously. .

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Drug Discovery World

APRIL 4, 2023

Join this free webinar to learn about the biggest challenges and opportunities facing the NGS oncology space. You will hear from Darrell Green, a lecturer in RNA Biology at Norwich Medical School, Panna Sharma, CEO of Lantern Pharma, as well as Dr Stephane Budel and Dr Miguel Edwards, Founding Partner and Partner at DeciBio.

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RNA Medical Schools Drugs Clinical Trials 130

Drug Discovery World

APRIL 3, 2023

Join this free webinar to learn about the biggest challenges and opportunities facing the NGS oncology space. You will hear from Darrell Green, a lecturer in RNA Biology at Norwich Medical School, Panna Sharma, CEO of Lantern Pharma, as well as Dr Stephane Budel and Dr Miguel Edwards, Founding Partner and Partner at DeciBio.

RNA 130

RNA Medical Schools Clinical Trials Drugs 130

Broad Institute

JULY 26, 2022

Researchers decipher how a gut bacterium influences immunity By Corie Lok July 26, 2022 Breadcrumb Home News Researchers decipher how a gut bacterium influences immunity Study finds a molecule made by the bacterium that helps moderate immune responses. Adapted from a press release issued by Harvard Medical School.

Research 52

Research Immune Response Medical Schools Disease 52

Drug Discovery World

MARCH 15, 2023

Researchers at the University of East Anglia have developed a new drug that works against all of the main types of primary bone cancer. First new treatment in 45 years Lead researcher Dr Darrell Green, from UEA’s Norwich Medical School, was inspired to study childhood bone cancer after his best friend died from the disease as a teenager.

Small Molecule 130

Small Molecule Medical Schools Drugs Clinical Trials 130

Drug Discovery World

DECEMBER 5, 2022

The research focuses on a group of small, ubiquitous viruses called ‘parvoviruses’ (from the Latin word ‘ parvus’ meaning ‘small’, ‘puny’ or ‘unimportant’). It was led by scientists at the MRC-University of Glasgow Centre for Virus Research (CVR) and University of Massachusetts Chan Medical School. .

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Virus Therapies Treatment Medical Schools 130

Drug Discovery World

APRIL 18, 2023

Register now. The post Register now to learn how NGS is informing oncology drug discovery appeared first on Drug Discovery World (DDW).

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RNA Medical Schools Clinical Trials Drugs 130

Drug Discovery World

JANUARY 9, 2023

In this early research, Khalid Shah, Professor of Neurosurgery at Harvard Medical School and Brigham and Women’s Hospital, and colleagues tested the vaccine in an advanced mouse model of brain cancer glioblastoma, with promising results. “Our

Medical Schools 130

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Drug Discovery World

APRIL 11, 2023

Register now. The post Webinar: Find out how NGS is informing oncology drug discovery appeared first on Drug Discovery World (DDW).

RNA 130

RNA Medical Schools Clinical Trials Drugs 130

Broad Institute

MAY 23, 2024

We conclude with an outlook for the future with “AI scientists” as generative agents capable of skeptical learning and reasoning to empower biomedical research.

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Medical Schools Research Drugs 45

Drug Discovery World

FEBRUARY 2, 2023

The last endocrine therapy approved was about 20 years ago, and effective endocrine options for this patient population are needed,” said Dr Aditya Bardia, Director of Breast Cancer Research at Mass General Cancer Center, Associate Professor at the Medicine Department at Harvard Medical School, and Principal Investigator for the EMERALD trial. “ESR1 (..)

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FDA Approval Therapies FDA Medical Schools 130

Broad Institute

AUGUST 8, 2024

at Harvard Medical School, where he conducted research with Pardis Sabeti on evolution of human genetic resistance to infectious disease. Tabrizi earned his M.D.

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Drug Discovery World

APRIL 24, 2023

Register now. The post Free webinar today: How is NGS informing oncology drug discovery?

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RNA Medical Schools Clinical Trials Drugs 130

Broad Institute

JUNE 18, 2024

Now researchers have developed a low-cost paper strip test that could allow more patients to find out which type of flu they have and get the right treatment. Myhrvold, who is currently an assistant professor at Princeton University, was a postdoctoral researcher in Sabeti’s lab when the study began. We’re excited to apply it to H5N1.”

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Virus RNA Medical Schools Laboratories 144

Drug Discovery World

OCTOBER 26, 2022

The researchers also showed that H84T BanLec protected mice from getting infected by the flu virus. . The genetically engineered version has been called H84T and worked against the viruses that cause AIDS, hepatitis C and influenza in tests in tissue and blood samples. .

Engineering 130

Engineering Virus Medical Schools International 130

Drug Discovery World

MAY 8, 2024

“No medication has been approved by the FDA for vaping cessation in the United States,” said lead author Nancy Rigotti, Director of Massachusetts General Hospital’s Tobacco Research and Treatment Center and a Professor of Medicine at Harvard Medical School.

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Clinical Trials Compliance Trials Drugs 183