Drug Target Review

JULY 1, 2024

As a non-opioid, SRP-001 also eliminates abuse potential, positioning it as a safer and effective drug candidate for the treatment of acute and neuropathic pain and migraine headache. How does SRP-001’s safety profile, especially concerning hepatotoxicity and nephrotoxicity, compare to other common pain medications?

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Treatment Clinical Trials Therapies Molecular Biology 59

The Pharma Data

MAY 13, 2021

Product Name: Varicose Veins Natural Treatment | Varicose Veins Home Treatment Program. Varicose Veins Natural Treatment | Varicose Veins Home Treatment Program is backed with a 60 Day No Questions Asked Money Back Guarantee. Most are not trained or knowledgeable in diet, nutrition, natural treatments, home remedies, etc.

Treatment 52

Treatment Doctors Production Medical Schools 52

Broad Institute

MARCH 6, 2024

Related news New project aims to map cellular variation in the healthy human brain Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have uncovered a strikingly similar suite of changes in gene activity in brain tissue from people with schizophrenia and from older adults.

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Broad Institute

AUGUST 19, 2024

A common fatty acid may help restore healthy vaginal bacteria after infection By Ari Navetta August 19, 2024 Breadcrumb Home A common fatty acid may help restore healthy vaginal bacteria after infection Treatments using oleic acid, a naturally occurring oil used in cells, could improve treatment of recurrent bacterial vaginosis infections.

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Hospitals Treatment Medical Schools Science 121

biobide

FEBRUARY 2, 2024

Pediatric cancers exhibit differences at the genetic level compared to the same form of adult disease, which may influence the selected treatment. Zebrafish Pioneers Advance in Pediatric Cancer Research and Treatment Increasing the survival rate is the primary goal when screening for cancer drugs.

Disease 59

Disease Medical Schools Pharma Companies Clinical Trials 59

Drug Target Review

APRIL 26, 2023

Scientists from the Massachusetts Institute of Technology (MIT) and the University of Massachusetts Medical School (UMass), US, have collaborated to create a novel type of nanoparticle that can deliver messenger RNA that encodes for beneficial proteins to the lungs.

RNA 98

RNA Medical Schools Engineering DNA 98

Broad Institute

OCTOBER 30, 2024

The results pave the way for future single-cell or spatially resolved studies that look at how cells surrounding a metastatic tumor impact its progression or treatment outcomes. Eventually, we hope that these methods can help inform the development of drugs or even guide patients’ individual treatments.”

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Research RNA Medical Schools Treatment 127

Broad Institute

FEBRUARY 16, 2024

The way that clinicians subdivide diabetes patients now is based on symptoms, but in this study, the frequency of genetic risk factors seems to vary among patients with youth-onset T2D,” said Jason Flannick , Broad associate member and assistant professor at Boston Children’s Hospital and Harvard Medical School. “We

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Medical Schools Hospitals Disease DNA 133

The Pharma Data

MAY 15, 2023

CHMP Adopts Positive Opinion Recommending Hepcludex® (Bulevirtide) for Full Marketing Authorization for the Treatment of Hepatitis Delta Virus (HDV) Gilead Sciences, Inc. Bulevirtide was initially granted conditional marketing authorisation in July 2020 to provide people living with HDV urgent access to treatment.

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Drug Target Review

SEPTEMBER 14, 2023

Dr Cristina Ureche from Hannover Medical School (MHH) guides us through the aseptic process of viral vector-based vaccines, and Dr Mark J. Steve O’Keeffe of Angry@Arthritis and Dr Ivan Martin of the University of Basel lead the charge in revolutionizing osteoarthritis treatment through innovative regenerative approaches.

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Vaccine Medical Schools Drugs Therapies 105

Broad Institute

OCTOBER 17, 2024

By Leah Eisenstadt October 17, 2024 Credit: Kevin Middleton, Broad Communications In the Bhattacharyya lab, researchers develop methods to quickly identify the most appropriate treatments for bacterial infections. The findings appear in the Journal of Clinical Microbiology (link).

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RNA Hospitals Laboratories Medical Schools 69

Broad Institute

SEPTEMBER 18, 2024

Gram-negative bacteria such as Enterobacteriaceae are a common cause of these infections and have few treatment options. Researchers at Keio University School of Medicine in Tokyo and the Broad Institute of MIT and Harvard have isolated 18 bacterial strains from stool from healthy people that could potentially be a more effective treatment.

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Medical Schools Disease Hospitals Treatment 114

Broad Institute

NOVEMBER 6, 2024

For some patients, this treatment results in striking and long-lasting remission — but for a subset, it triggers complications ranging from mild rash to potentially deadly brain and heart inflammation. We know a bit more in terms of treatments to try, but they don’t always work.

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Research Immune Response Hospitals Therapies 124

Broad Institute

JUNE 18, 2024

Now researchers have developed a low-cost paper strip test that could allow more patients to find out which type of flu they have and get the right treatment.

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Virus RNA Laboratories Medical Schools 144

Alta Sciences

MARCH 27, 2024

Eryn has a wealth of expertise in diverse therapeutic areas and, after her experiences with battling cancer, a commitment to advancing the pharmaceutical industry by merging conventional and alternative treatments into one model. Not really, although I contemplated medical school for a while.

Drug Development 52

Drug Development Medical Schools Pharma Companies Drugs 52

Policy Prescription

OCTOBER 22, 2024

Rome, MD, MPH Author Affiliations: Program on Regulation, Therapeutics, and Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts (Lalani, Hwang, Kesselheim, Rome); Harvard Medical School, Boston, Massachusetts (Lalani, Hwang, Kesselheim, Rome).

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Online Pharmacies Pharmacy Drugs FDA Approval 113

The Pharma Data

JUNE 2, 2023

With only one currently approved treatment option, I see HS patients with a tremendous need for alternatives that reduce the disabling physical symptoms of HS, improve the emotional burden and help partially avoid invasive surgery, if treating early,” said Professor Christos C.

Medical Schools 52

Medical Schools Treatment Disease Therapies 52

Broad Institute

MAY 30, 2023

She realized the importance of her role in keeping the worms healthy, so she could later study their gene expression and behavior in response to different drug treatments. I told him I was struggling with my classes and that I didn’t think I'd make it to medical school. And if I did, I wouldn’t be happy.

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Research Medical Schools Doctors Science 89

Broad Institute

NOVEMBER 13, 2023

Liquid biopsies enable clinicians to find and analyze tumor DNA in a patient’s blood sample to detect cancer early, monitor cancer recurrence, assess the patient’s response to treatment, and measure other clinically important features in real time, without invasive procedures.

DNA 116

DNA Medical Schools Treatment Therapies 116

Broad Institute

JUNE 21, 2023

Now, researchers at the Broad Institute of MIT and Harvard have found that treatment with continuous hypoxia — low-oxygen conditions comparable to levels at a Mount Everest base camp — restores balance and coordination in a mouse model of Friedreich’s ataxia. A few treatments stood out.

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Treatment Disease Molecular Biology Medical Schools 98

The Pharma Data

SEPTEMBER 7, 2021

The first patients have been enrolled in a phase 1 randomized placebo-controlled clinical trial to study a therapeutic vaccine for opioid use disorder developed by researchers at the University of Minnesota Medical School. The study plans to enroll up to 45 volunteers.

Clinical Trials 52

Clinical Trials Vaccine Trials Medical Schools 52

Broad Institute

JUNE 28, 2023

The findings, published today in Nature , could lead to new ways of guiding cancer treatment or developing targeted drugs. Towards treatments In nearly one-third of all cancers in TCGA, one arm of chromosome 8 is missing, but researchers had never been sure why this aneuploidy is so common.

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DNA Medical Schools Treatment Research 122

The Pharma Data

JANUARY 3, 2021

Anecdotal feedback from Foralumab-treated patients was positive and suggests that the treatment was well-tolerated. Among the positive results patients reported, the most common was that the treatment resulted in the rapid improvement in smell sensation, which is frequently lost in COVID-19 patients.”.

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Clinical Trials Science Treatment Trials 40

Drug Target Review

NOVEMBER 8, 2023

Cell therapies hold immense promise for revolutionising the treatment of some of the most challenging diseases, but several technological and logistical hurdles stand in the way of unlocking their full potential. These patients typically fail frontline chemotherapies within 8 months of treatment and have few options for second line therapies.

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Therapies Engineering Treatment Molecular Biology 116

Drug Target Review

AUGUST 28, 2024

What are the main challenges currently faced in the treatment of chronic liver diseases, and how does Resolution Therapeutics aim to address these challenges? Once a patient develops advanced cirrhosis/end-stage liver disease there are no specific therapies to significantly avoid major decompensations and death in the next few years.

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Therapies Disease Engineering Medical Schools 114

Advarra

FEBRUARY 28, 2023

Rebecca Lee Crumpler Rebecca Lee Crumpler was one of the first African American women to graduate from medical school and to practice medicine. Crumpler’s focus on the care of women and children and her dedication to research led her to publish “A Book of Medical Discourses” in 1883. and abroad.

Medical Schools 52

Medical Schools Laboratories Clinical Research Treatment 52

On Medicine

APRIL 6, 2023

I have a background in Biomedical Engineering prior to medical school and a particular interest in global health and healthcare in resource-limited settings. I continued working in this field and I did my PhD thesis on anthracycline-induced cardiotoxicity during and after treatment for childhood cancer.

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Medical Schools Hospitals Treatment International 52

KIF1A

NOVEMBER 1, 2024

Among them, 2 KAND patients are currently receiving treatment with KIF1A ASO-001, and 5 more KAND patients have been accepted to receive the same ASO. By enrolling in this online research study, you are not just a participant; you are a crucial partner in the fight to understand and ultimately find treatments for KAND.

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Treatment Medical Schools Research Disease 52

Drug Target Review

JULY 13, 2023

Drug discovery is a complex and vital field that continually seeks to identify new therapeutic targets and develop effective treatments. He holds a PhD in Biology from The Rockefeller University and an MD from Weill Cornell Medical College. In 2022, Isaac was named one of Endpoints News 20 under 40 in Biopharma.

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Disease Small Molecule Cell Biology Drugs 98

The Pharma Data

SEPTEMBER 18, 2020

Promising Phase 2 data has been released at the European Society for Medical Oncology (ESMO) Virtual Congress 2020 for Sanofi and Regeneron’s jointly-developed PD-1 inhibitor Libtayo (cemiplimab) in the treatment of locally advanced basal cell carcinoma (BCC) in patients for whom hedgehog inhibitor (HHI) therapy is not applicable.

Medical Schools 52

Medical Schools Trials Therapies Hospitals 52

Broad Institute

JUNE 1, 2023

Without prompt diagnosis and treatment, hypertensive disorders of pregnancy (HDPs) can lead to organ failure and potentially fatal complications. But scientists lack the tools to predict, prevent, and treat them. Buu Truong, a computational researcher and postdoctoral fellow in Natarajan’s lab, was a co-first author as well.

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Doctors Medical Schools Hospitals DNA 133

The Pharma Data

APRIL 22, 2023

While the obesity pandemic grows, especially amongst low-income communities, effective medical treatments remain inaccessible for millions in need. Our study highlights the inequality in pricing that exists for effective anti-obesity medications, which are largely unaffordable in most countries.

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Medical Schools Licensing Licensing Treatment 40

Drug Target Review

FEBRUARY 26, 2024

Rather than solely identifying tumour-associated mutations which can be specifically targeted for effective treatment, we now need to consider how non-mutational events play into both the development of the primary tumour and the development of therapy resistance. Dr Alani received her M.D.

Therapies 59

Therapies Molecular Biology Regulations Medical Schools 59

The Pharma Data

JANUARY 17, 2021

Ophthalmologists are physicians who have completed four years of medical school and four years of residency training. Treatments they help administer include patching therapy, prisms and convergence exercises. Danielle Natale, an optometrist at the Krieger Eye Institute in Baltimore, said in an institute news release.

Medical Schools 52

Medical Schools Doctors Treatment Disease 52

Drug Target Review

MAY 16, 2024

Symptom-based treatment is often accompanied by undesirable side effects. Examples include insulin for the treatment of diabetes and human somatotropin to promote physical growth. SCFAs are capable of immunomodulation 8 with effective treatment, not immunosuppression which treats symptoms and has multiple potential side effects.

Disease 64

Disease Therapies Medical Schools Treatment 64

The Pharma Data

SEPTEMBER 1, 2020

. Novo Nordisk has launched in the UK the first ‘protein in a pill’ treatment for type II diabetes. Despite a number of treatments on the market, 40% of adults with the disease in the UK fail to achieve target blood sugar of ?

Medical Schools 52

Medical Schools Treatment Clinical Development Disease 52

Broad Institute

JANUARY 25, 2024

“This could potentially help with disease prevention — if we know from someone’s retinal image that they are at high risk of developing glaucoma or cardiovascular disease in the future, we could refer them for follow-up screening or preventative treatment.”

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