Pharmacokinetics of panobinostat: Inter-species difference in metabolic stability [Metabolism, Transport, and Pharmacogenetics]
ASPET
FEBRUARY 26, 2024
Panobinostat also showed inter-strain and inter-species differences in the in vitro plasma stability; and was stable in human plasma. Importantly, the plasma stability in various mouse strains was not reflected in the in vivo systemic pharmacokinetic behavior of panobinostat.
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