addgene Blog

AUGUST 13, 2024

It is possible to produce your own recombinant antibodies with some molecular biology and cell culture experience. Since recombinant antibodies conveniently allow for unlimited production, reliable expression, and easy distribution as DNA (Trimmer, 2020), you may be interested in using them in your own experiments.

Molecular Biology 74

Molecular Biology DNA Production 74

Science Daily: Pharmacology News

JUNE 20, 2024

Scientists have been studying for years how the body, specifically on the molecular side, changes in space. Recently, findings depict how the modern tools of molecular biology and precision medicine can help guide humanity into more challenging missions beyond where we've already been.

Molecular Biology 89

Molecular Biology Research 89

SCIENMAG: Medicine & Health

FEBRUARY 6, 2024

Dr. Wu is an associate professor in the Department of Molecular Biology at the University of Texas Southwestern Medical Center, U.S.A. Evanston, IL—The International Society for Stem Cell Research (ISSCR) is honoring Jun Wu, Ph.D. with the 2024 ISSCR Outstanding Young Investigator Award. Credit: ISSCR Evanston, IL—The […]

Molecular Biology 83

Molecular Biology International Research 83

SCIENMAG: Medicine & Health

SEPTEMBER 7, 2023

Details on the findings, which were reported in the September 7 issue of Nature Structural & Molecular Biology [DOI: 10.1038/s41594-023-01085-6], could […]

Molecular Biology 96

Molecular Biology Drugs Research 96

addgene Blog

JULY 16, 2024

There are several facilities nationwide where you can obtain excellent quality, high titer rAAV ( including Addgene! ), but you can also generate rAAVs in your own lab with standard molecular biology tools and tissue culture experience. Here, we’ll go over the basics of rAAV production.

Molecular Biology 52

Molecular Biology Production 52

SCIENMAG: Medicine & Health

JULY 4, 2023

The European Molecular Biology Organization (EMBO) has announced today that it will award the lifetime honor of EMBO Membership to Luísa Figueiredo, group leader at the Instituto de Medicina Molecular João Lobo Antunes (iMM, Lisbon, Portugal), in recognition of the excellence of her research and outstanding achievements in the life sciences.

Molecular Biology 90

Molecular Biology International Science Research 90

Broad Institute

OCTOBER 24, 2024

Here, DePalma focused on integrating biomaterials, microfabrication, quantitative image analysis, and cell and molecular biology techniques to generate mechanically tunable engineered heart tissue platforms. Prior to joining Bayer and the PCL, DePalma earned his Ph.D.

Molecular Biology 52

Molecular Biology Engineering Laboratories Disease 52

biobide

NOVEMBER 24, 2023

In the realm of molecular biology and toxicology, the terms "genotoxicity" and "mutagenicity" are often used interchangeably, but they refer to distinct concepts with unique implications. Understanding these differences is crucial for assessing the potential risks associated with various substances and environmental factors.

Molecular Biology 64

Molecular Biology 64

Broad Institute

DECEMBER 13, 2023

Hung Group, Infectious Disease and Microbiome Program Michael Bogaev Princeton University Molecular Biology (major), B.A., Spanish (minor) Genetic Pertubation Platform (GPP) Mohammed Mutaher Harvard University Human Developmental and Regenerative Biology (major), B.A.,

Molecular Biology 52

Molecular Biology Cell Biology Science Engineering 52

Covalent Modifiers

MARCH 30, 2024

Lingyang Kong, Sang-Jun Park Wonpil Im Journal of Molecular Biology , 2024 [link] Molecular modeling and simulation serve an important role in exploring biological functions of proteins at the molecular level, which is complementary to experiments.

Molecular Biology 84

Molecular Biology Drugs 84

addgene Blog

JULY 27, 2023

The Retroviridae (commonly called retrovirus) family — of which HIV is a member — may seem like an unlikely candidate to use as a viral vector, but retroviruses have been developed into some of the most widely used tools in molecular biology. Retroviruses” is an umbrella term which encompasses 1.)

Molecular Biology 68

Molecular Biology 68

SCIENMAG: Medicine & Health

AUGUST 3, 2023

In a study published today in Cell, one of the most prominent peer-reviewed scientific journals in the field of Biochemistry & Molecular Biology, scientists from the National University of Singapore (NUS) and Imperial College London have discovered a new way by which bacteria transmit their genes, enabling them to evolve much faster than previously (..)

Virus 60

Virus Molecular Biology 60

Broad Institute

MAY 14, 2024

“Bill Studier’s development of T7 phage RNA polymerase for use in preparing RNA templates for multiple uses in research labs worldwide has been a truly revolutionary technical advance for the entire field of molecular biology,” said Joan Steitz, the Sterling Professor of Molecular Biophysics and Biochemistry at Yale University.

RNA 84

RNA Production Molecular Biology Laboratories 84

Chemical Biology and Drug Design

DECEMBER 6, 2023

However, the pharmacodynamic mechanism and molecular target of SP-FC in the treatment of HS are still unclear. Therefore, this study is intended to explore the mechanism and target of SP-FC in the treatment of HS through network pharmacology combined with in vitro cell and molecular biology experiments.

Molecular Biology 100

Molecular Biology Protein Expression Treatment Regulations 100

Drug Target Review

NOVEMBER 23, 2023

About the author Dr William Schafer Group Leader at MRC Laboratory of Molecular Biology William Schafer is a neuroscientist who has investigated conserved principles by which neurons and neural circuits control behaviour.

Therapies 98

Therapies Molecular Biology Laboratories Government 98

Fierce BioTech

JUNE 6, 2023

Harwell molecular biology spherical nucleic acid rare diseases Adaptive Biotechnologies Resource Type Whitepaper harwell logo.png Tue, 06/06/2023 - 09:31 Content Channel Devices Clinical Data Biotech Content Channel Fierce Biotech Homepage Landing Page Url More Info Byline Sponsored by: Harwell

Science 52

Science Therapies Molecular Biology Government 52

Broad Institute

JULY 17, 2024

As of now, papers describing three of these machine learning tools have been published, in the Journal of Chemical Information and Modeling , Molecular Biology of the Cell , and Chemical Research in Toxicology. Molecular Biology of the Cell. A fourth is in the works. DOI: 10.1021/acs.chemrestox.4c00015. Seal S, et al.

Pharmacokinetics 84

Pharmacokinetics Molecular Biology Drugs FDA 84

LifeSciVC

AUGUST 5, 2024

Earlier in my career, graduate-level molecular biology departments arose in universities at a time when those technologies were transformative to the science. That has largely fallen out of favor, and the technologies of molecular biology are today essential technical skills for the cell biologist and geneticist.

Molecular Biology 87

Molecular Biology Production Drug Development Small Molecule 87

DrugBank

MAY 15, 2024

But as molecular biology has advanced, so too has our approach to finding new drugs. Advancements in technology and a deeper understanding of molecular biology are beginning to turn the tide. Researchers would sift through natural extracts , hoping to stumble upon a compound that exhibited beneficial effects.

Small Molecule 82

Small Molecule Molecular Biology Drugs Disease 82

Drug Target Review

FEBRUARY 19, 2024

I always found science fascinating, but I really fell in love with it in high school when I was introduced to biochemistry and molecular biology. Biochemistry and molecular biology fascinated me in school. Can you tell us about your journey in the field of STEM and the challenges you encountered along the way?

Molecular Biology 110

Molecular Biology Science Protein Expression Production 110

FDA Law Blog: Drug Discovery

MAY 1, 2024

Sarah graduated with a cum laude degree in Cell and Molecular Biology from Towson University, a M.P.H. Sarah’s expertise will contribute to our mission of helping drug and biologic companies navigate the pathways from discovery to commercialization. from Johns Hopkins Bloomberg School of Public Health, and a J.D.

Drug Development 52

Drug Development Molecular Biology Compliance Clinical Trials 52

The Pharma Data

FEBRUARY 25, 2022

. “The SARS-CoV-2 vaccines target the spike protein, but this protein is under strong selection pressure and, as we have seen with Omicron, can undergo significant mutations,” said Joyce Jose, assistant professor of biochemistry and molecular biology, Penn State. 25) in the journal Communications Biology.

FDA Approval 52

FDA Approval Molecular Biology FDA Virus 52

Drug Target Review

OCTOBER 3, 2024

Methods in Molecular Biology. Journal of Molecular Biology. Recombinant Anti-idiotypic Antibodies in Ligand Binding Assays for Antibody Drug Development. 2021;291–306. Prassler J, Thiel S, Pracht C, et al. 2011 Oct 1;413(1):261–78. Harth S, Ten Haaf A, Loew C, et al.

Molecular Biology 52

Molecular Biology Pharmacokinetics Laboratories Animal Testing 52

Conversations in Drug Development Trends

NOVEMBER 12, 2024

These advanced therapeutics harness the power of molecular biology to improve human health. Patients with previously terminal cancer diagnoses are experiencing renewed hope from cellular immunotherapies, including but not limited to adoptive cell therapies such as CAR T , to target and eliminate the cancerous threat.

Therapies 72

Therapies Clinical Supply Clinical Trials Molecular Biology 72

Drug Target Review

OCTOBER 13, 2023

For each of these ten diverse growth conditions, they cultivated 25 cultures and subsequently subjected the various samples to molecular biology techniques (referred to as multi-omics) that enable simultaneous analysis of all transcribed genes, all produced proteins, and all metabolic products within a cell.

Molecular Biology 105

Molecular Biology Doctors Research Production 105

BMG Labtech

MARCH 11, 2024

This is reflected in scientific discoveries across many research disciplines including immunology , molecular biology , medicine, and diagnostics. Specific areas where they have had a wide impact include virology , bacteriology, biotechnology , fungal biology, cancer and oncology (e.g.

Vaccine 98

Vaccine Molecular Biology Laboratories Pharmacokinetics 98

Broad Institute

OCTOBER 23, 2024

By applying machine learning and molecular biology to the logic of when and where CREs work, we can leverage that knowledge using generative AI to build tools for modulating gene expression in new ways experimentally and, perhaps one day, therapeutically." Chan School of Public Health. "By

Research 136

Research DNA Laboratories Molecular Biology 136

sptlabtech

JUNE 9, 2023

Using our innovative true positive displacement technology, firefly is fully compatible with all molecular biology reagents, viscous and volatile, as well as bead suspension, making it an ideal solution for genomics workflows. What benefits can you expect to see from making the switch to automated liquid handling with firefly?

Molecular Biology 52

Molecular Biology DNA Laboratories Production 52

Codon

JULY 17, 2024

I want to see amateur biology thrive, and while a lot of regulations exist for a reason, I’m unconvinced that molecular biology requires all the crazy expensive equipment that has become associated with it. I mean, how did people do molecular biology fifty or one hundred years ago?

Laboratories 88

Laboratories Engineering Molecular Biology Science 88

Alta Sciences

JUNE 11, 2024

Our experts have over five years of experience with CRISPR gene-editing therapeutics in nonhuman primates (NHPs) and extensive expertise in bioanalysis for biodistribution studies, in addition to many molecular biology platforms , such as ligand binding assays (LBA), NAbs, TAbs, flow cytometry , and ELISpot. About the Author Dr.

Therapies 52

Therapies Molecular Biology Immune Response Science 52

sptlabtech

JUNE 9, 2023

Using our innovative true positive displacement technology, firefly is fully compatible with all molecular biology reagents, viscous and volatile, as well as bead suspension, making it an ideal solution for genomics workflows. What benefits can you expect to see from making the switch to automated liquid handling with firefly?

Laboratories 89

Laboratories Molecular Biology DNA Engineering 89

Drug Target Review

NOVEMBER 27, 2023

Dr Worland was an NIH postdoctoral fellow in molecular biology at Harvard University and completed a Ph.D. Dr Worland has served on the board of directors of Tracon Pharmaceuticals, Inc., a biopharmaceutical company, since February 2015. in Chemistry at the University of California, Berkeley. He received his B.S.

Molecular Biology 86

Molecular Biology Therapies Pharmaceuticals Treatment 86

Drug Target Review

APRIL 19, 2024

Sibylla’s scientific founders come from very different scientific fields that do not usually speak to each other, such as theoretical physics, molecular biology and pharmaceutical chemistry. And so, I have been the managerial co-founder and CEO of Sibylla since 2017. This multidisciplinary approach is at the heart of Sibylla.

Molecular Biology 111

Molecular Biology Research Pharmaceuticals Small Molecule 111

Drug Target Review

MARCH 15, 2024

He has a post-doctorate in virology, viral pathogenesis, viral vector development, and vaccines evaluation from Harvard Medical School, and a PhD in virology/molecular biology. Anis also serves on the scientific and editorial advisory board of Genetic Engineering News at Mary Ann Liebert, Inc.

Engineering 105

Engineering Molecular Biology Protein Expression Medical Schools 105

The Pharma Data

MARCH 16, 2022

As Professor Patrick Cramer, Professor at the Max-Planck Institute for Multidisciplinary Sciences and Director of the Molecular Biology Department, emphasized in his congratulatory speech: “Kai Johnsson is a world-leading research scientist in chemical biology.

Cell Biology 52

Cell Biology Molecular Biology Science Laboratories 52

DrugBaron

FEBRUARY 16, 2021

The first technological leap was the invention of hybridoma technology, by César Milstein together with his post-doc Georges Köhler working at the world-famous Laboratory of Molecular Biology in Cambridge.

Molecular Biology 130

Molecular Biology Small Molecule Engineering Laboratories 130

The Pharma Data

FEBRUARY 22, 2021

Born in 1970, the British and American research scientist has been Director of the Department of Microbiome Research at the Max Planck Institute for Developmental Biology in Tübingen since 2016. Before, she was associate professor at Cornell University in the Department of Molecular Biology and Genetics.

Molecular Biology 40

Molecular Biology Science Vaccine Laboratories 40