Codon

FEBRUARY 13, 2024

Regulators traditionally want to see a single, stable, well-characterized drug before giving the green light for it to be tested in a clinical trial, not dozens of different viruses; let alone ones that are best found in unappealing places like sewage , hospital waste, or bird poop.

Therapies 135

Therapies Virus DNA Clinical Trials 135

Codon

APRIL 2, 2024

I was reading a lot of molecular biology papers about different systems, especially circadian clocks, and also a book called Biological Feedback , by Thomas and D’Ari, that sketched out really simple models for different kinds of feedback circuits. So many kinds of people have contributed to biology in different ways.

RNA 56

RNA Engineering Molecular Biology Synthetic Chemistry 56

Codon

JULY 27, 2023

.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecular biology and biophysics. You can read all of them here. And it’s true, but only in an incomplete way.

Therapies 52

Therapies RNA DNA Engineering 52

Codon

JULY 27, 2023

.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecular biology and biophysics. You can read all of them here. And it’s true, but only in an incomplete way.

Therapies 52

Therapies RNA DNA Engineering 52

Codon

JUNE 26, 2023

For context, the AAV9 that is often used in gene therapies has a packaging limit of 4,700 DNA bases.) Future Nobel Laureate, Paul Berg, narrated the video, which quickly became a cult classic moment in molecular biology history. plasmidsaurus @arjunrajlab (Regulation in biology is incredible. Paper by Sha G.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

JUNE 26, 2023

For context, the AAV9 that is often used in gene therapies has a packaging limit of 4,700 DNA bases.) Future Nobel Laureate, Paul Berg, narrated the video, which quickly became a cult classic moment in molecular biology history. plasmidsaurus @arjunrajlab (Regulation in biology is incredible. Paper by Sha G.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Agency IQ

JANUARY 19, 2024

The History of the ICH Q5A(R1) Guideline The International Council on Harmonization (ICH) Q5A(R1) Guideline, Viral Safety Evaluation of Biotechnology Products Derived from Cell Lines of Human or Animal Origin , was first adopted by regulators in 1999. This bulk product contains both the final product (e.g., also received some additions.

Virus 40

Virus Science Production FDA 40