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doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of untreatable, drug-resistant infections.
Prevention of viral contamination is especially important as it may not be apparent that cells have been contaminated with a virus using conventional detection methods. Likewise, the selection of a cell line that was developed using a virus increases the risk of potential viral contamination.
.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecularbiology and biophysics. ” The tool was crafted with a virus, called GIL16. No longer.
.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecularbiology and biophysics. ” The tool was crafted with a virus, called GIL16. No longer.
A phage is a virus that infects bacteria. For context, the AAV9 that is often used in gene therapies has a packaging limit of 4,700 DNA bases.) Future Nobel Laureate, Paul Berg, narrated the video, which quickly became a cult classic moment in molecularbiology history. ” Bacteriophages infect a bacterium.
A phage is a virus that infects bacteria. For context, the AAV9 that is often used in gene therapies has a packaging limit of 4,700 DNA bases.) Future Nobel Laureate, Paul Berg, narrated the video, which quickly became a cult classic moment in molecularbiology history. ” Bacteriophages infect a bacterium.
In parallel, we are exploring the technical performance of circVec in other viral vectors, as well as non-viral approaches which we expect will surpass virus-based vector-format as the state-of-the-art solutions for gene therapy in the future. We are now running follow-up experiments to track the advantage long-term.
I’ve chosen these two because I think they are the linchpin by which we’ll be able to build broadly useful AI models for cell and molecularbiology. But looking ahead to the second bottleneck, what does it mean to say that biology is “complex”?
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