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Europe: Where is the drug discovery innovation?

Drug Discovery World

Europe is traditionally a life sciences powerhouse, with a strong tradition in pharmaceutical discovery. The oldest, still active pharmaceutical company worldwide, Merck, started life in 1668 in Darmstadt, Germany. Members of the European Federation of Pharmaceutical Industries and Associations (EFPIA) spent €41.5

Drugs 147
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The evolution of cell therapy to address unmet medical needs

Drug Target Review

The mission of Lineage Cell Therapeutics is to deliver on some of the early promises of cell therapy. Cell therapy as a concept is a wonderful idea, but many of the early efforts never generated the kind of clinical data that gets people excited and leads to new medicines. Hearing aids also have all sorts of deficits.

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Where is the promise for plant-based medicines? Part 1: Cannabis  

Drug Discovery World

Significantly, in January 2023, the FDA finalised a 2020 draft guidance outlining how sponsors and investigators can conduct clinical trials for certain drugs containing cannabis or cannabis-derived compounds without running afoul of federal law 2. Jazz Pharmaceuticals has supplied the cannabidiol for the trials at no cost.

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The future outlook for mRNA therapies

Drug Discovery World

Reece Armstrong explores the potential and future opportunities for mRNA-based therapies. For instance, consider how at the end of 2018, the mRNA therapies market was valued at $3.43 At the start of 2024, the first patients in a clinical trial investigating an mRNA cancer therapy were dosed.

Therapies 130
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Scaling Phage Therapy

Codon

Tom Ireland writes about the companies and technologies that are reimagining phage therapy. Soon after its publication, scientists, journalists, and investors were revisiting ‘phage therapy’ as a promising alternative to our failing antibiotics. Read it on our website here. Illustration by David S. Always free.

Therapies 118
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What it takes to make cancer research more inclusive

Drug Discovery World

These observations may come to light in the clinic, but these disparities can be attributed to every phase of the drug development pipeline – clinical trials, translational research and, ultimately, drug discovery. . Instead, molecular markers are more accurate indicators of the patient’s associated risks. .

Research 130
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From the Top: Adele Hannigan, Antibody Analytics

Drug Discovery World

I started off studying chemistry at the University of Edinburgh, and it was during an industrial placement as a synthetic organic chemist for a pharmaceutical company (Organon) that my interest in biology was piqued. It was my first foray into investigational drug testing in clinical trials and I found it very rewarding.